3,088 research outputs found
Vibrational corrections to transition properties
The vibrational contributions to second-order transition properties are considered in the framework of the Born—Oppenheimer approximation. It is shown that the usual formula for vibrational second-order transition matrix elements is incomplete and needs to be supplemented by a term of purely vibrational origin. This pure vibrational contribution is calculated for vibrational transition polarizabilities in LiH and BeF and found to be quite
significant. Its inclusion in theoretically calculated data for the Raman intensities appears to be necessary
How often is cytologically unsuspected nipple discharge a symptom of underlying breast cancer?
Long-term results of postoperative radiotherapy in adult patients with incompletely excised infratentorial low grade astrocytoma
Physicochemical Characterization and Dissolution Studies of Solid Dispersions of Clotrimazole with Pluronic F127
Purpose: To evaluate the physicochemical properties of clotrimazole (CLT) solid dispersion with Pluronic F127 (PLU).Methods: Solid dispersions of the antifungal drug, clotrimazole, were prepared with Pluronic F127 using grinding (PM) and fusion (FUS) methods. Physicochemical characterization of the dispersions were performed using differential scanning calorimetry (DSC), x-ray powder diffraction (XRPD) and Fourier transform infrared spectroscopy (FTIR). In vitro drug release was carried out using the rotating disc method.Results: These studies showed that there was no chemical interaction between CLT and PLU. Release studies on the SDs showed a significant (> 90-fold) improvement in dissolution rate compared to pure CLT. The greatest increase in dissolution (< 80 %) was observed for the solid dispersion (CLT/PLU) prepared by FUS in the ratio 60:40 % w/w.Conclusion: The results demonstrate that the developed solid dispersion system is a suitable approach for enhancing the dissolution rate of CLT.Keywords: Clotrimazole, Pluronic F127, Solid dispersion, Dissolution, Differential scanning calorimetry, Phase diagra
An analysis of interplanetary solar radio emissions associated with a coronal mass ejection
Coronal mass ejections (CMEs) are large-scale eruptions of magnetized plasma
that may cause severe geomagnetic storms if Earth-directed. Here we report a
rare instance with comprehensive in situ and remote sensing observa- tions of a
CME combining white-light, radio, and plasma measurements from four different
vantage points. For the first time, we have successfully applied a radio
direction-finding technique to an interplanetary type II burst detected by two
identical widely separated radio receivers. The derived locations of the type
II and type III bursts are in general agreement with the white light CME recon-
struction. We find that the radio emission arises from the flanks of the CME,
and are most likely associated with the CME-driven shock. Our work demon-
strates the complementarity between radio triangulation and 3D reconstruction
techniques for space weather applications
Coulomb Corrections for Interferometry Analysis of Expanding Hadron Systems
The problem of the Coulomb corrections to the two-boson correlation functions for the systems formed in ultra-relativistic heavy ion collisions is considered for large effective system volumes. The modification of the standard zero-distance correction (so called Gamow or Coulomb factor) has been proposed for such a kind of systems. For the 1r+1r+ and [(+[(+ correlation functions the analytical calculations of the Coulomb correction are compared with the exact numerical results
Postoperative hypofractionated radiotherapy of patients with glioblastoma: three courses of irradiation separated by 2 or 4 week intervals. A preliminary report on a randomized trial
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