Detection of the primary scintillation light from dense Ar, Kr and Xe with novel photosensitive gaseous detectors

The detection of primary scintillation light in combination with the charge or secondary scintillation signals is an efficient technique to determine the events t=0 as well as particle / photon separation in large mass TPC detectors filled with noble gases and/or condensed noble gases. The aim of this work is to demonstrate that costly photo-multipliers could be replaced by cheap novel photosensitive gaseous detectors: wire counters, GEMs or glass capillary tubes coupled with CsI photocathodes. We have performed systematic measurements with Ar, Kr and Xe gas at pressures in the range of 1-50 atm as well as some preliminary measurements with liquid Xe and liquid Ar. With the gaseous detectors we succeeded in detecting scintillation light produced by 22 keV X-rays with an efficiency of close to 100%. We also detected the scintillation light produced by bs (5 keV deposit energy) with an efficiency close to 25%. Successful detection of scintillation from 22 keV gammas open new experimental possibilities not only for nTOF and ICARUS experiments, but also in others, like WIMPs search through nuclear recoil emission

The Successful Operation of Hole-type Gaseous Detectors at Cryogenic Temperatures

We have demonstrated that hole-type gaseous detectors, GEMs and capillary plates, can operate up to 77 K. For example, a single capillary plate can operate at gains of above 10E3 in the entire temperature interval between 300 until 77 K. The same capillary plate combined with CsI photocathodes could operate perfectly well at gains (depending on gas mixtures) of 100-1000. Obtained results may open new fields of applications for capillary plates as detectors of UV light and charge particles at cryogenic temperatures: noble liquid TPCs, WIMP detectors or LXe scintillating calorimeters and cryogenic PETs.Comment: Presented at the IEEE Nuclear Science Symposium, Roma, 200

Measurement of Atmospheric Neutrino Oscillations with a High-Density Detector

We propose an experiment to test the hypothesis that the reported anomaly on atmospheric neutrino fluxes is due to nu_mu nu_x oscillations. It will rely both on a disappearance technique, exploiting the method of the dependence of the event rate on L/E, which was recently shown to be effective for detection of neutrino oscillation and measurement of the oscillation parameters, and on an appearance technique, looking for an excess of muon-less events at high energy produced by upward-going tau neutrinos. The detector will consist of iron planes interleaved by limited streamer tubes. The total mass will be about 30 kt. The possibility of recuperating most of the instrumentation from existing detectors allows to avoid R&D phases and to reduce construction time. In four years of data taking, this experiment will be sensitive to oscillations nu_mu nu_x with Delta m^2 > 10^-4 eV^2 and a mixing near to maximal, and answer the question whether nu_x is a sterile or a tau neutrino

Observation of inertial energy cascade in interplanetary space plasma

We show in this article direct evidence for the presence of an inertial energy cascade, the most characteristic signature of hydromagnetic turbulence (MHD), in the solar wind as observed by the Ulysses spacecraft. After a brief rederivation of the equivalent of Yaglom's law for MHD turbulence, we show that a linear relation is indeed observed for the scaling of mixed third order structure functions involving Els\"asser variables. This experimental result, confirming the prescription stemming from a theorem for MHD turbulence, firmly establishes the turbulent character of low-frequency velocity and magnetic field fluctuations in the solar wind plasma

The development of gaseous detectors with solid photocathodes for low temperature

There are several applications and fundamental research areas which require the detection of VUV light at cryogenic temperatures. For these applications we have developed and successfully tested special designs of gaseous detectors with solid photocathodes able to operate at low temperatures: sealed gaseous detectors with MgF2 windows and windowless detectors. We have experimentally demonstrated, that both primary and secondary (due to the avalanche multiplication inside liquids) scintillation lights could be recorded by photosensitive gaseous detectors. The results of this work may allow one to significantly improve the operation of some noble liquid gas TPCs.Comment: Presented at the X Vienna Conference on Instumentation, Vienna, February 200

Anti-Insulin Receptor Autoantibodies Are Not Required for Type 2 Diabetes Pathogenesis in NZL/Lt Mice, a New Zealand Obese (NZO)-Derived Mouse Strain

The New Zealand obese (NZO) mouse strain shares with the related New Zealand black (NZB) strain a number of immunophenotypic traits. Among these is a high proportion of B-1 B lymphocytes, a subset associated with autoantibody production. Approximately 50% of NZO/HlLt males develop a chronic insulin-resistant type 2 diabetes syndrome associated with 2 unusual features: the presence of B lymphocyte–enriched peri-insular infiltrates and the development of anti-insulin receptor autoantibodies (AIRAs). To establish the potential pathogenic contributions ofBlymphocytes and AIRAs in this model, a disrupted immunoglobulin heavy chain gene (Igh-6) congenic on the NZB/BlJ background was backcrossed 4 generations into the NZO/HlLt background and was then intercrossed to produce mice that initially segregated for wild-type versus the mutant Igh-6 allele and thus permitted comparison of syndrome development. A new flow cytometric assay (AIRA binding to transfected Chinese hamster ovary cells stably expressing mouse insulin receptor) showed IgM and IgG subclass AIRAs in serum from Igh-6 intact males, but not in Igh6null male serum. However, the absence of B lymphocytes and antibodies distinguishing mutant from wild-type males failed to significantly affect diabetes-free survival. The Igh6nullmales gained weight less rapidly than wild-type males, probably accounting for a retardation, but not prevention, of hyperglycemia. Thus, AIRA and the Blymphocyte component of the peri-insulitis in chronic diabetics were not essential either to development of insulin resistance or to eventual pancreatic beta cell failure and loss. A new substrain, designated NZL, was generated by inbreeding Igh-6 wild-type segregants. Currently at the F10 generation, NZL mice exhibit the same juvenile-onset obesity as NZO/HlLt males, but develop type 2 diabetes at a higher frequency (> 80%). Also, unlike NZO/HlLt mice that are difficult to breed, the NZL/Lt strain breeds well and thus offers clear advantages to obesity/diabetes researchers

“Simultaneous and integrated neutron-based techniques for material analysis of a metallic ancient flute“

A metallic 19th century flute was studied by means of integrated and simultaneous neutron-based techniques: neutron diffraction, neutron radiative capture analysis and neutron radiography. This experiment follows benchmark measurements devoted to assessing the effectiveness of a multitask beamline concept for neutron-based investigation on materials. The aim of this study is to show the potential application of the approach using multiple and integrated neutron-based techniques for musical instruments. Such samples, in the broad scenario of cultural heritage, represent an exciting research field. They may represent an interesting link between different disciplines such as nuclear physics, metallurgy and acoustics

Developments and the preliminary tests of Resistive GEMs manufactured by a screen printing technology

We report promising initial results obtained with new resistive-electrode GEM (RETGEM) detectors manufactured, for the first time, using screen printing technology. These new detectors allow one to reach gas gains nearly as high as with ordinary GEM-like detectors with metallic electrodes; however, due to the high resistivity of its electrodes the RETGEM, in contrast to ordinary hole-type detectors, has the advantage of being fully spark protected. We discovered that RETGEMs can operate stably and at high gains in noble gases and in other badly quenched gases, such as mixtures of noble gases with air and in pure air; therefore, a wide range of practical applications, including dosimetry and detection of dangerous gases, is foreseeable. To promote a better understanding of RETGEM technology some comparative studies were completed with metallic-electrode thick GEMs. A primary benefit of these new RETGEMs is that the screen printing technology is easily accessible to many research laboratories. This accessibility encourages the possibility to manufacture these GEM-like detectors with the electrode resistivity easily optimized for particular experimental or practical applications