Three years continuous record of the Earth’s magnetic field at Concordia Station (DomeC, Antarctica)

The magnetic observatory deployed at DomeC, Antarctica, in the French-Italian base known as Concordia hasnow been permanently running for more than three years. This paper focuses on these long-term results whichare more relevant for an observatory intended to provide absolute values of the field. The problems whichemerged in this fairly long record are discussed and solutions suggested to upgrade the observatory to the standardsof an absolute one (i.e. Intermagnet standards).Mailing address: Dr. Aude Chambodut, Ecole et Observatoiredes Sciences de la Terre 5, rue Descartes 67084, StrasbourgCedex, France; e-mail: [email protected]

Piccole storie di mare. Il paesaggio marino nelle narrazioni dei film festival green italiani (2005-2020)

Negli ultimi anni, i film festival hanno ampliato gli orizzonti di significato del paesaggio marino con molteplici riflessioni ispirate a tematiche ambientali. In questo contesto, abbiamo preso in esame dieci festival del cinema dedicati all’ecologia e all’ambiente al fine di comprenderne gli obiettivi e il rapporto con il territorio. Esplorandone la programmazione dal 2005 al 2020, abbiamo realizzato una carta geografica sulle tematiche ambientali legate al mare trattate esplicitamente o nel sottotesto filmico, come l’inquinamento industriale delle acque e della costa, i problemi derivanti dalla pesca a strascico o la perdita di biodiversità marina. La carta ha permesso, inoltre, di identificare le aree geografiche sovra o sotto-rappresentate dai film green italiani in concorso

Three years continuous record of the Earth’s magnetic field at Concordia Station (DomeC, Antarctica)

The magnetic observatory deployed at DomeC, Antarctica, in the French-Italian base known as Concordia has<br />now been permanently running for more than three years. This paper focuses on these long-term results which<br />are more relevant for an observatory intended to provide absolute values of the field. The problems which<br />emerged in this fairly long record are discussed and solutions suggested to upgrade the observatory to the standards<br />of an absolute one (i.e. Intermagnet standards).<br />Mailing address: Dr. Aude Chambodut, Ecole et Observatoire<br />des Sciences de la Terre 5, rue Descartes 67084, Strasbourg<br />Cedex, France; e-mail: [email protected]

Altered plasma levels of decanoic acid in colorectal cancer as a new diagnostic biomarker

Colorectal cancer (CRC) is one of the most common tumors in developed countries. The five-year survival rate decreases depending on how advanced the CRC is when first diagnosed. Screening has been proven to greatly reduce mortality from colorectal cancer, but an ideal screening tool is far from being established. Here, we aimed to discover and validate early CRC biomarkers by means of an untargeted/targeted metabolomic approach. A preliminary untargeted analysis of plasma lipids performed on a small patient cohort (30 plasma samples) revealed some alterations that occurred in the presence of this tumor. In particular, medium-chain fatty acids with between six and twelve carbon atoms (C6-C12) were found to be the lipid class that showed the most marked changes upon the development of CRC. In order to evaluate the utility of this lipid class as diagnostic CRC biomarkers, a further study based on a wider cohort of patients (117 plasma samples) was performed. Using a targeted approach, these fatty acids were quantified in plasma samples by means of fast gas chromatography coupled to a time-of-flight analyzer. Plasma samples from patients with CRCs at different tumor stages were analyzed and compared to those from healthy subjects, ulcerative colitis patients, high-grade dysplasia adenoma patients, and breast cancer patients in order to test the specificity and sensitivity of these possible biomarkers. Results revealed significant differences among the considered groups in terms of their C6, C8, C10, and C12 fatty acid plasma concentrations. In particular, receiver operating characteristic (ROC) curves obtained for the C10 fatty acid gave an area under the curve of 0.8195 along with a sensitivity of 87.8 % and a specificity of 80 %, strongly suggesting that it could be a valuable early diagnostic biomarker of CRC

Adherence to HIV treatment : results from a 1-year follow-up study

We evaluated adherence to HIV treatments every 4 months during one year in 63 HIV-infected subjects using combination therapies including a protease inhibitor. A total of 18 subjects reported a high level of adherence, 14 in two evaluations, and eight a low level of adherence in all the three evaluations. The remaining 23 subjects (36.5%) reported different levels of adherence to treatment in the three evaluations. These findings suggest that the level of adherence to treatment changes markedly for each patient over tim

Where does this image take you? A visual tale from a workshop on geographical imaginations

This work is authored by a group of Ph.D. students and academics who attended a workshop on visual methodologies in the framework of the Scuola di alta formazione in geografia organised by AGeI (Association of Italian Geographers), 2022 edition. By visually reporting the workshop activities we aim at reflecting on the creative power of images in expanding geographical imaginations and its potential in the teaching of geography. The paper is shaped as a visual essay in which images and text do not refer directly to each other but rather aim at creating an imaginative reading flow