303 research outputs found
Delegation Success and Policy Failure: Collective Delegation and the Search for Iraqi Weapons of Mass Destruction
Tierney argues that international delegation can have important consequences, even for powerful states. In particular, he contends that the US delegation of inspection authority to United Nations weapons inspectors and to the International Atomic Energy Association after the Gulf War of 1990-91 entailed significant sovereignty costs by affecting the timing and costliness of the subsequent 2003 US invasion of Iraq. Among other things, he notes that the inspectors\u27 independent behavior made it much more difficult for the US to assemble the type of multilateral coalition that would share the costs as it had in the earlier Gulf War. Tierney also notes that this example shows how different states can pay different costs as the result of the same episode of international delegation
Sustainable waterplanning : a study of Kristianstad municipality
Idag stÀlls det allt större krav för utformandet av vÄra stÀder för
att anpassa oss för framtiden. Ett stort mÄl för utvecklingen av
vÄra stÀder Àr att gÄ i riktning mot ett mer hÄllbart samhÀlle.
NÄgot som har hanterats ganska lite i stadsplaneringen Àr
vattenfrÄgorna i stÀderna. Vattnet har behandlats som en
sjÀlvklarhet i Sverige och nÀr man har velat göra sig av med det
sÄ har man behandlat det som en obegrÀnsad resurs. Med EU:s
nya ramdirektiv riktas blickar mot vattenfrÄgorna i vilka man ska
arbeta för en lÄngsiktig hÄllbar hantering.
Intentionen med detta examensarbete har varit att skapa en
övergripande förstÄelse inom Àmnet hÄllbarvattenplanering.
Litteraturstudien inom Àmnet vattenplanering har Àmnats
ligga till grund för fördjupningsdel dÀr det har utförts en
gestaltning av en dagvattendamm/översvÀmningsyta i
Kristianstad kommun. Förstudien har gjorts i litteratur om
vattenplanering och hÄllbarhet, vidare har en litteraturstudie
gjorts av dagvattensystem. Som steg tre i fördjupningen har
en studie gjorts av Kristianstads uppkomst och utveckling samt
en övergripande studie av vattenhistoriska hÀndelser i stadens
vattensystem.
Gestaltningen har utförts utifrÄn förutsÀttningar pÄ platsen
vilken ligger i utkanten av stadskĂ€rnan i omrĂ„det ĂsterĂ€ng/
Björket. Analyser har gjorts för att skapa en förstÄelse av platsen
för att skapa en fungerande design till planeringsförslaget.
Analysmetoder som har anvÀnts har varit Lynchs
lÀsbarhetsanalys, SWOT-analys och en vattengenomslÀpplighets
analys av omrÄdet. Arbetet har haft till avsikt att diskutera ett
aktuellt Àmne och tillÀmpa nÄgra tankar pÄ ett konkret förslag.The claims in the design of our cities are growing today, as an
adaption for the future. A big goal for the development of our
cities is the development towards a more sustainable society.
Something that has been handled quite little in the past in the
townplanning is water issues in the cities. The water has been
managed as something that is taken for granted in Sweden.
When it needed to be removed was it handled as an endless
resource. With the new framework for water by EU, was the
glance pointed on water issues, about working for a long-term
sustainable management of water.
The intentions for this thesis have been to get a broad
understanding in the field of sustainable waterplanning. The
literature study in the subject waterplanning was supposed to be
a broad study for the in-deep part, where a design of a daywater
pond/flooding area in Kristianstad municipality has been
designed. As pilot study have a literature study about planning
and sustainability been used, after have a literature study been
made about daywatersystems. As third step has a study been
made about the origin and development of the city and also a
broad study about water historical circumstances of the water
systems in the city.
The design has been developed from circumstances on the
site. The project site is placed in the border of the central city,
in the ĂsterĂ€ng/Björket area. Analysis has been made to get
an understanding about the place and as a result of create an
operational design for the planning suggestion. Analysis methods
that have been used are Kevin LynchÂŽs legibility analysis, SWOT
â analysis and a waterpermeability analysis of the area. The
work has had a goal to discuss an actual topic and practice some
thoughts on a concrete suggestion
StÄndortsanpassad vÀxtanvÀndning pÄ bjÀlklag
The purpose for this essay is to investigate claims
trees and shrubs have to survive and grow on concrete
roof foundation and create good design from those
conditions. At first is described what requirements
there are on the planting areas to make it comfortable
for the plants. After that is a planting list with chosen
plants that is supposed to survive on the concrete
roof presented. Then is the site and its presumptions
presented. Finally my design is presented and is continued
with a discussion and reflection about the essay
and the knowledge gained from it.
The difficulty as I can see with the essay has been for
example to know exactly what plant's that grows and
survive on the site that I have chose for my design.
It's not really until you have tried the plant's on the
site as you can say for real if they are going to like the
spot or not. It is such narrow margins for the plants
to survive on, as places on roofs can be such extreme
situations. The extreme situation makes it also very interesting
for the design.Syftet med detta kandidatarbete Àr att undersöka vilka
förutsÀttningar som krÀvs för att trÀd och buskar ska
överleva och trivas pÄ ett betongbjÀlklag och dÀrefter
göra en gestaltning utifrÄn dessa förutsÀttningar.
Först presenteras vilka förutsÀttningar vÀxterna mÄste
ha för att trivas och hur man byg ger upp planteringsytorna.
Efter det presenteras en vÀxtlista med utvalda
vÀxter som ska klara av de förutsÀttningar som krÀvs
pÄ ett takbjÀlklag. DÀrefter presenteras platsens förutsÀttningar.
Slutligen presenteras gestaltningsförslaget
för att avslutas med en diskussion och en reflektion
kring uppsatsen som helhet och lÀrdomar som har
kommit utifrÄn arbetet.
SvÄrigheten som jag kan se med erfarenheter utifrÄn
detta arbete Àr exempelvis att det Àr mycket svÄrt att
veta exakt vilka vÀxter som i praktiken skulle klara sig
pÄ den plats som jag har anvÀnt för min gestaltning.
Det Àr egentligen inte förrÀn man har prövat
vÀxterna pÄ platsen som man kan sÀga om det fungerar
eller inte. Att platser pÄ tak ger extrema förhÄllanden
gör att vÀxter har smÄ marginaler att spela med för att
överleva, men det Àr ocksÄ det som kan skapa intressanta
kompositioner
Humans as Reservoir for Enterotoxin Geneâcarrying Clostridium perfringens Type A
Humans may play a role in the transmission of gastrointestinal diseases caused by C. perfringens
Partial intersubjectivity and sufficient understandings for current practical purposes : On a specialized practice in Swedish conversation
This paper explores issues of intersubjectivity and shared understanding as they arise in dyadic spoken interaction. Using data from Swedish conversations, we approach the topic by focusing on the functions of a reactive construction that occurs in situations when a linguistic expression (x) has been used in a prior utterance, and this expression is found to be only partially acceptable in the situation at hand. It is therefore reacted to by one of the interlocutors, and negotiated in a new turn initiated by x-°a-x, i.e. a unit in which two identical copies of x are conjoined by °a âandâ, and then expanded by a supporting argument. The pragmatic functions of the construction include that of suggesting a sufficient clarification of what should be a reasonable situated meaning and an intersubjective basis for ensuing talk.Peer reviewe
Cause-specific mortality in women with breast cancer in situ
The long-term mortality remains unknown in women diagnosed with breast cancer in
situ (BCIS). Here, we assessed the cause-specific mortality in BCIS patients.
This population-based cohort study included 12,243 women diagnosed with BCIS in
Sweden between 1980 and 2011. Patients were followed until death, emigration, or
31 December 2013, whichever came first. The 30-year cumulative incidence of
breast cancer-specific mortality was 6.3%, which is considerably lower than 49.7%
observed for other-cause mortality. Women diagnosed with BCIS were more likely to
die from breast cancer (standardized mortality ratio [SMR], 3.85; 95% CI,
3.47-4.27) but less likely to die from cardiovascular disease (SMR, 0.88; 95% CI,
0.82-0.95) than women in the general population. Specifically, the SMRs for
breast cancer-specific mortality decreased over time from 5.19 (95% CI,
3.95-6.81) among BCIS diagnosed during 1980-1989 to 3.03 (95% CI, 2.35-3.91)
among those diagnosed during 2000-2011. Furthermore, higher risk of death from
other causes was seen among those with older age at BCIS diagnosis, lower levels
of education, nulliparity, higher Charlson Comorbidity Index, and being
hospitalized before BCIS diagnosis; whereas, lower risk of death from breast
cancer was seen among BCIS diagnosed in the later time period and those with
younger age at first birth. We conclude that most women diagnosed with BCIS die
from causes other than breast cancer, which highlights the need for actions not
only to reduce nonbreast cancer mortality but also to identify patient where
extensive curative BCIS treatment is not adding to survival.NoneAccepte
Breast cancer genetic risk profile is differentially associated with interval and screen-detected breast cancers
Background: Polygenic risk profiles computed from multiple common susceptibility alleles for breast
cancer have been shown to identify women at different levels of breast cancer risk. We
evaluated whether this genetic risk stratification can also be applied to discriminate between
screen-detected and interval cancers, which are usually associated with
clinicopathological and survival differences.
Patients and methods: A 77-SNP polygenic risk score (PRS) was constructed for breast cancer overall and by
estrogen-receptor (ER) status. PRS was inspected as a continuous (per standard deviation
increment) variable in a case-only design. Modification of the PRS by mammographic density
was evaluated by fitting an additional interaction term.
Results: PRS weighted by breast cancer overall estimates was found to be differentially associated
with 1,865 screen-detected and 782 interval cancers in the LIBRO-1 study (age-adjusted
ORperSD [95% confidence interval]=0.91 [0.83-0.99], p=0.023). The association was found to
be more significant for PRS weighted by ER-positive breast cancer estimates (ORperSD=0.90
[0.82-0.98], p=0.011). This result was corroborated by two independent studies (combined
ORperSD=0.87 [0.76-1.00], p=0.058) with no evidence of heterogeneity. When enriched for
âtrueâ interval cancers among nondense breasts, the difference in the association with PRS in
screen-detected and interval cancers became more pronounced (ORperSD=0.74 [0.62-0.89],
p=0.001), with a significant interaction effect between PRS and mammographic density
(pinteraction=0.017).
Conclusion: To our knowledge, this is the first report looking into the genetic differences between screendetected
and interval cancers. It is an affirmation that the two types of breast cancer may have
unique underlying biology.Swedish Research CouncilSwedish Cancer SocietyStockholm County CouncilBreast Cancer Theme Centre Consortium (BRECT)Accepte
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