329 research outputs found
Lectin-enzyme binding assays : development of the technique and applications in biochemistry and medicine
The aim of this work is to determine if lectins can be used in "sandwich"
ELISA techniques so that the glycosylation of specific proteins in mixtures could
be characterised in a fast and sensitive way without prior purification of the
protein. Furthermore, the feasability of lectin-enzyme binding assays will be
explored in various ways to assess the lectin specificity, and to detect the binding
of lectins to normal plasma glycoproteins and their disease-associated glycoform
The effect of high dose inhaled corticosteroids on wheeze in infants after respiratory syncytial virus infection: randomised double blind placebo controlled trial
Objective To determine whether early initiated anti-inflammatory therapy with prolonged high dose inhaled glucocorticoids influences the occurrence and severity of recurrent wheeze after respiratory syncytial virus related lower respiratory tract infections
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Reāevaluation of stannous chloride (E 512) as food additive
The Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion reāevaluating the safety of stannous chloride and stannous chloride dihydrate (E 512) as food additives. The Panel considered that adequate exposure and toxicity data were available. Stannous chloride is only permitted as food additives in one food category and no reply on the actual use level of stannous chloride (E 512) as a food additive and on its concentration in food was provided by any interested party. According to the Mintel's Global New Products Database (GNPD), stannous chloride was not labelled on any products in the EU nor in Norway. The regulatory maximum level exposure assessment scenario is based on the maximum permitted levels (MPLs) for stannous chloride (E 512), which is 25 mg Sn/kg. The mean exposure to stannous chloride (E 512) from its use as a food additive was below 1.3 Ī¼g Sn/kg body weight (bw) per day for all age groups. The 95th percentile of exposure to stannous chloride (E 512) ranged from 0.0 Ī¼g Sn/kg bw per day in all groups to 11.2 Ī¼g Sn/kg bw per day in adults. Absorption of stannous chloride from the gastrointestinal tract is low there is no concern with respect to carcinogenicity and genotoxicity. Gastrointestinal irritation was reported in humans after ingestion of a bolus dose of 40 mg Sn. The Panel concluded that stannous chloride (E 512) is of no safety concern in this current authorised use and use levels
Unified approach for cluster variation method calculations of phase diagrams in fcc substitutional alloys with interstitial species
Verbreding van de Lange Viestraat
Te Utrecht, 1931. Voor de oprichting van een passende nieuwe bewoning was nodig de afbraak en onteigening van het diep achter de percelen doorlopende Hotel de l'Europe aan het Vredenbur
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