197 research outputs found
Managing the Cultural Differences in Spain: When Talking about Interculturality Means Talking about Immigrant's Culture
For many years, Spain is experimenting the phenomenon of immigration and implementing procedures normatively orientated according to the contexts, but sharing the main goal: integration. Those orientative processes have been first guided by multiculturalism and then evolving toward certain forms of interculturalism. On the base of this consideration it is necessary to deeply consider the theory debate on multi- and interculturalism, in order to consider the assumption and operational translations. Through the normative production and Third Sector discourses, emerge the trend of relating interculturalism to dynamics that are exclusively tied to the presence of migrant population in the Country. This essay is based on a qualitative research in which clearly emerged that, at least in Andalucia, but we can generalize to the whole country, the cultural managing process brought to interculturalism has been often difficult and did not help to definitely overcome assimilationist risks, typical above all of social operators at local level, for this reason we need to redefine the sense of "us". DOI: 10.5901/mjss.2016.v7n1s1p6
A guide to the equipment, methods and procedures for the prevention of risks, emergency response and mitigation of the consequences of accidents: Part I
This report is the first part of a dilogy which aims to be a compendium for regulators without a specific background in risk and safety assessment. It describes the state-of-the-art of the safety-related equipment, methods, procedures and projects available nowadays for the prevention of risks, the emergency response and the mitigation of the consequences of accidents.
While the present report addresses the above topics from a generic perspective, the second part, currently in preparation, focuses on the particular challenges of the Nordic Seas.
The review is based on the retrieval and analysis of a large number of open source information, along with personal contacts with Authorities and HSE representatives of several major oil and gas operators. This helps the reader go into further details and better appreciate the latest technological advancements in offshore safety as a consequence of the lessons learnt from the Macondo Accident.JRC.C.3-Energy Security, Distribution and Market
Treatment of perinfarction recurrent ventricular fibrillation by percutaneous pharmacological block of left stellate ganglion
A patient suffering from an acute myocardial infarction presented on the seventh and eighth days of hospitalization recurrent episodes of ventricular fibrillation refractory to antiarrhythmic treatment. The life-threatening ventricular fibrillation was suppressed by percutaneous pharmacological block of the left stellate ganglion
Efficacy of hormonal suppression in a patient with chyluria due to lymphangioleiomyomatosis
Lymphangioleiomyomatosis (LAM) is a rare lung disease affecting almost exclusively young women, characterised by abnormal proliferation of atypical smooth muscle cells. We describe a young woman presenting with chyluria secondary to the presence of a large retroperitoneal lymphangioleiomyoma. Immunohistochemical analysis revealed HMB45-negative LAM cells (HMB45 staining is absent only in rare cases) expressing low levels of estrogen receptors. Estrogen suppressive treatment with triptoreline, a synthetic analogue of Gn-RH, resulted in dramatic reduction of the retroperitoneal mass size. The role of estrogens in the pathogenesis of LAM remains poorly understood, and hormonal therapy is still debated, but this case suggests that at least in some LAM patients, possibly those with HMB45-negative disease and estrogen receptor expression, hormonal therapy may be effective in controlling the disease process
COVID-19 Is a Multifaceted Challenging Pandemic Which Needs Urgent Public Health Interventions
Until less than two decades ago, all known human coronaviruses (CoV) caused diseases so mild that they did not stimulate further advanced CoV research. In 2002 and following years, the scenario changed dramatically with the advent of the new more pathogenic CoVs, including Severe Acute Respiratory Syndome (SARS-CoV-1), Middle Eastern respiratory syndrome (MERS)-CoV, and the new zoonotic SARS-CoV-2, likely originated from bat species and responsible for the present coronavirus disease (COVID-19), which to date has caused 15,581,007 confirmed cases and 635,173 deaths in 208 countries, including Italy. SARS-CoV-2 transmission is mainly airborne via droplets generated by symptomatic patients, and possibly asymptomatic individuals during incubation of the disease, although for the latter, there are no certain data yet. However, research on asymptomatic viral infection is currently ongoing worldwide to elucidate the real prevalence and mortality of the
disease. From a clinical point of view, COVID-19 would be defined as “COVID Planet “ because it presents as a multifaceted disease, due to the large number of organs and tissues infected by the virus. Overall, based on the available published data, 80.9% of patients infected by SARS-CoV-2 develop a mild disease/infection, 13.8% severe pneumonia, 4.7% respiratory failure, septic shock, or multi-organ failure, and 3% of these cases are fatal, but mortality parameter is highly variable in dfferent countries. Clinically, SARS-CoV-2 causes severe primary interstitial viral pneumonia and a “cytokine storm syndrome”, characterized by a severe and fatal uncontrolled systemic inflammatory response triggered by the activation of interleukin 6 (IL-6) with development of endothelitis and generalized thrombosis that can lead to organ failure and death. Risk factors include advanced age and comorbidities including hypertension, diabetes, and cardiovascular disease. Virus entry occurs
via binding the angiotensin-converting enzyme 2 (ACE2) receptor present in almost all tissues and organs through the Spike (S) protein. Currently, SARS-CoV-2 infection is prevented by the use of masks, social distancing, and improved hand hygiene measures. This review summarizes the current knowledge on the main biological and clinical features of the SARS-CoV-2 pandemic, also focusing on the principal measures taken in some Italian regions to face
Migrazioni e inclusione. L'agire agapico di singoli, gruppi e istituzioni
Il fenomeno delle migrazioni si è sviluppato in modo considerevole negli ultimi dieci anni con conseguenze imprevedibili e spostamenti di persone mai verificatisi nella storia dell’umanitĂ . Con questo articolo si offrono alcune prospettive di studio sui principali temi collegati ai fenomeni migratori, con particolare attenzione alle motivazioni dei soggetti mediante un approccio qualitativo. Tali prospettive sono state utilizzate per analizzare tre casi rilevanti in cui ai processi migratori si associano azioni orientate in senso agapico per lo sviluppo di nuove socialitĂ
A top-down proteomic approach reveals a salivary protein profile able to classify Parkinson's disease with respect to Alzheimer's disease patients and to healthy controls
Parkinson's disease (PD) is a complex neurodegenerative disease with motor and non-motor symptoms. Diagnosis is complicated by lack of reliable biomarkers. To individuate peptides and/or proteins with diagnostic potential for early diagnosis, severity and discrimination from similar pathologies, the salivary proteome in 36 PD patients was investigated in comparison with 36 healthy controls (HC) and 35 Alzheimer's disease (AD) patients. A top-down platform based on HPLC-ESI-IT-MS allowed characterizing and quantifying intact peptides, small proteins and their PTMs (overall 51). The three groups showed significantly different protein profiles, PD showed the highest levels of cystatin SA and antileukoproteinase and the lowest of cystatin SN and some statherin proteoforms. HC exhibited the lowest abundance of thymosin & beta;4, short S100A9, cystatin A, and dimeric cystatin B. AD patients showed the highest abundance of & alpha;-defensins and short oxidized S100A9. Moreover, different proteoforms of the same protein, as S-cysteinylated and S-glutathionylated cystatin B, showed opposite trends in the two pathological groups. Statherin, cystatins SA and SN classified accurately PD from HC and AD subjects. & alpha;-defensins, histatin 1, oxidized S100A9, and P-B fragments were the best classifying factors between PD and AD patients. Interestingly statherin and thymosin & beta;4 correlated with defective olfactory functions in PD patients. All these outcomes highlighted implications of specific proteoforms involved in the innate-immune response and inflammation regulation at oral and systemic level, suggesting a possible panel of molecular and clinical markers suitable to recognize subjects affected by PD
Detection of Chlamydophila pneumoniae and human herpesvirus 8 in primary cutaneous anaplastic large-cell lymphoma: a case report
Organic micropollutants in wet and dry depositions in the Venice Lagoon
Atmospheric transport is an important route by which pollutants are conveyed from the continents to
both coastal and open sea. The role of aerosol deposition in the transport of polycyclic aromatic hydrocarbons
(PAHs), polychlorobiphenyls (PCBs) and polybromodiphenyls ethers (PBDEs) to water and soil
systems has been evaluated by measuring their concentrations in wet and dry depositions to the Venice
Lagoon. The organic micropollutant flux data indicate that they contribute to the total deposition flux in
different ways through wet and dry deposition, showing that the prevalent contribution derives from wet
deposition. The fluxes calculated for PBDEs, showed the prevalence of 47, 99, 100 and 183 congeners,
both in dry and wet fluxes. With regard to PCBs, the flux of PPCB for wet deposition is in the same order
of magnitude of the diffusive flux at the air–water interface. The PAH fluxes obtained in the present study
are similar to those obtained in previous studies on the atmospheric bulk deposition to the Venice
Lagoon. The ratios between Phe/Ant and Fl/Py indicate that the pollutants sources are pyrolytic, deriving
from combustion fuels
- …