5,548 research outputs found
The Triple-Ring Nebula around SN1987A: Fingerprint of a binary merger
Supernova 1987A, the first naked-eye supernova observed since Kepler's
supernova in 1604, defies a number of theoretical expectations. Its anomalies
have long been attributed to a merger between two massive stars that occurred
some 20,000 years before the explosion, but so far there has been no conclusive
proof that this merger took place. Here, we present three-dimensional
hydrodynamical simulations of the mass ejection associated with such a merger
and the subsequent evolution of the ejecta, and we show that this accurately
reproduces the properties of the triple-ring nebula surrounding the supernova.Comment: 16 pages (including 7 pages of supplementary material), 2 figures
(reduced in size), appeared in Science on 23rd February 2007. Animations
available at http://www.sciencemag.org/cgi/content/full/315/5815/1103/DC1 or
http://www-astro.physics.ox.ac.uk/~tsm/scipaper/index.htm
Sarcopenic obesity and risk of cardiovascular disease and mortality: a population-based cohort study of older men.
OBJECTIVES: To examine associations between sarcopenia, obesity, and sarcopenic obesity and risk of cardiovascular disease (CVD) and all-cause mortality in older men.
DESIGN: Prospective cohort study.
SETTING: British Regional Heart Study.
PARTICIPANTS: Men aged 60-79 years (n = 4,252).
MEASUREMENTS: Baseline waist circumference (WC) and midarm muscle circumference (MAMC) measurements were used to classify participants into four groups: sarcopenic, obese, sarcopenic obese, or optimal WC and MAMC. The cohort was followed for a mean of 11.3 years for CVD and all-cause mortality. Cox regression analyses assessed associations between sarcopenic obesity groups and all-cause mortality, CVD mortality, CVD events, and coronary heart disease (CHD) events.
RESULTS: There were 1,314 deaths, 518 CVD deaths, 852 CVD events, and 458 CHD events during follow-up. All-cause mortality risk was significantly greater in sarcopenic (HR = 1.41, 95% CI = 1.22-1.63) and obese (HR = 1.21, 95% CI = 1.03-1.42) men than in the optimal reference group, with the highest risk in sarcopenic obese (HR = 1.72, 95% CI = 1.35-2.18), after adjustment for lifestyle characteristics. Risk of CVD mortality was significantly greater in sarcopenic and obese but not sarcopenic obese men. No association was seen between sarcopenic obesity groups and CHD or CVD events.
CONCLUSION: Sarcopenia and central adiposity were associated with greater cardiovascular mortality and all-cause mortality. Sarcopenic obese men had the highest risk of all-cause mortality but not CVD mortality. Efforts to promote healthy aging should focus on preventing obesity and maintaining muscle mass
Diet quality in older age: the influence of childhood and adult socio-economic circumstances.
Socio-economic gradients in diet quality are well established. However, the influence of material socio-economic conditions particularly in childhood, and the use of multiple disaggregated socio-economic measures on diet quality have been little studied in the elderly. In the present study, we examined childhood and adult socio-economic measures, and social relationships, as determinants of diet quality cross-sectionally in 4252 older British men (aged 60-79 years). A FFQ provided data on daily fruit and vegetable consumption and the Elderly Dietary Index (EDI), with higher scores indicating better diet quality. Adult and childhood socio-economic measures included occupation/father's occupation, education and household amenities, which combined to create composite scores. Social relationships included social contact, living arrangements and marital status. Both childhood and adult socio-economic factors were independently associated with diet quality. Compared with non-manual social class, men of childhood manual social class were less likely to consume fruit and vegetables daily (OR 0·80, 95 % CI 0·66, 0·97), as were men of adult manual social class (OR 0·65, 95 % CI 0·54, 0·79), and less likely to be in the top EDI quartile (OR 0·73, 95 % CI 0·61, 0·88), similar to men of adult manual social class (OR 0·66, 95 % CI 0·55, 0·79). Diet quality decreased with increasing adverse adult socio-economic scores; however, the association with adverse childhood socio-economic scores diminished with adult social class adjustment. A combined adverse childhood and adulthood socio-economic score was associated with poor diet quality. Diet quality was most favourable in married men and those not living alone, but was not associated with social contact. Diet quality in older men is influenced by childhood and adulthood socio-economic factors, marital status and living arrangements
Anisotropic mass ejection in binary mergers
We investigate the mass loss from a rotationally distorted envelope following
the early, rapid in-spiral of a companion star inside a common envelope. For
initially wide, massive binaries (M_1+M_2=20M_{\odot}, P\sim 10 yr), the
primary has a convective envelope at the onset of mass transfer and is able to
store much of the available orbital angular momentum in its expanded envelope.
Three-dimensional smoothed particle hydrodynamics calculations show that mass
loss is enhanced at mid-latitudes due to shock reflection from a torus-shaped
outer envelope. Mass ejection in the equatorial plane is completely suppressed
if the shock wave is too weak to penetrate the outer envelope in the equatorial
direction (typically when the energy deposited in the star is less than about
one-third of the binding energy of the envelope). We present a parameter study
to show how the geometry of the ejecta depends on the angular momentum and the
energy deposited in the envelope during a merging event. Applications to the
nearly axisymmetric, but very non-spherical nebulae around SN1987A and Sheridan
25 are discussed, as well as possible links to RY Scuti and the Small
Magellanic Cloud object R4.Comment: 10 pages, 11 figures, accepted for publication in MNRAS. Figs 1, 2
and 10 reduced in siz
Plastic shrinkage cracking of concrete - Roles of osmotic suction
Plastic shrinkage cracking of concrete occurs when the stresses arising in the concrete, due to a combination of suction and restraints of deformation such as reinforcement or formwork, equal its strength. However, three different types of suctions should be distinguished, namely total, matric and osmotic suctions. Although the total suction comprises matric and osmotic suctions, it is often used interchangeably with matric suction, with the underlying unconfirmed assumption that either the osmotic suction or its effect is negligible. In this paper, after a discussion of the pore moisture suctions and strength of unsaturated early-age concrete, experimental investigations of the suctions arising in, and the tensile strength and shear strength of, fly ash mixed with solutions of different osmotic suctions are described. It was found that osmotic suction has negligible effect on the shear and tensile strength, and hence, by inference, the inter-particle stresses in the fly ash mixture and early-age concrete. This strongly suggests that the role played by osmotic suction in the plastic shrinkage cracking of concrete is minimal and, accordingly, justifies the focus of earlier researchers on matric suction only
Association of Maximum Temperature With Sedentary Time in Older British Men.
BACKGROUND: Sedentary behaviour is very common in older adults and a risk factor for mortality. Understanding determinants of sedentary behaviour may help in defining strategies aimed to reduce the time spent sedentary. The degree of difference in sedentary time attributable to varying temperatures has not been yet estimated in older men. METHODS: Men aged 71-91 years participating in an established UK population-based cohort study were invited to wear an Actigraph GT3x accelerometer for one week in 2010-12. Outcome was sedentary time (<1.5 Metabolic Equivalent of Task) in minutes per day. Associations between daily outdoor maximum temperature and accelerometer-measured sedentary time were estimated using multilevel models. RESULTS: 43% (1361/3137) of invited men participated in the study and provided adequate data. Men spent on average 615 minutes in sedentary time per day (72% of the total accelerometer-wear time). After adjusting for covariates, men spent 26 minutes more per day (p<0.001) in sedentary time when temperatures were in the lowest (-3.5; 9.2°C) versus highest quintile (19.1; 29.5°C). CONCLUSIONS: Sedentary time in older adults is highest at lowest temperatures, typically recorded in winter. Findings are relevant for guidelines: interventions may consider targeting older men in winter providing recommendations for minimising sedentariness on daily basis
Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study.
OBJECTIVE: We estimated associations of time of day with cardiovascular disease (CVD) risk factors measured in older men. METHODS: CVD risk factors (markers of inflammation and haemostasis, and cardiac markers) were measured on one occasion between 08:00 and 19:00 hours in 4252 men aged 60-79 years from the British Regional Heart Study. Linear models were used to estimate associations between time of day and risk factors. When an association was found, we examined whether the relationship between risk factors and cardiovascular mortality was affected by the adjustment for time of day using survival analyses. RESULTS: N-terminal pro-brain natriuretic peptide (NT-proBNP) levels increased by 3.3% per hour (95% CI 1.9% to 4.8%), interleukin-6 (IL-6) increased by 2.6% per hour (95% CI 1.8% to 3.4%), while tissue plasminogen activator (t-PA) decreased by 3.3% per hour (95% CI 3.7% to 2.9%); these associations were unaffected by adjustment for possible confounding factors. The percentages of variation in these risk factors attributable to time of day were less than 2%. In survival analyses, the association of IL-6, NT-proBNP and t-PA with cardiovascular mortality was not affected by the adjustment for time of day. C reactive protein, fibrinogen, D-dimer, von Willebrand factor and cardiac troponin T showed no associations with time of day. CONCLUSIONS: In older men, markers of inflammation (IL-6), haemostasis (t-PA) and a cardiac marker (NT-proBNP) varied by time of day. The contribution of time of day to variations in these markers was small and did not appear to be relevant for the CVD risk prediction
Finite N Fluctuation Formulas for Random Matrices
For the Gaussian and Laguerre random matrix ensembles, the probability
density function (p.d.f.) for the linear statistic
is computed exactly and shown to satisfy a central limit theorem as . For the circular random matrix ensemble the p.d.f.'s for the linear
statistics and are calculated exactly by using a constant term identity
from the theory of the Selberg integral, and are also shown to satisfy a
central limit theorem as .Comment: LaTeX 2.09, 11 pages + 3 eps figs (needs epsf.sty
Does total volume of physical activity matter more than pattern for onset of CVD? A prospective cohort study of older British men.
AIMS: With increasing age, physical inactivity and sedentary behaviour levels increase, as does cardiovascular disease (CVD) incidence. We investigate how device-measured sedentary behaviour and physical activity (PA) are related to CVD onset in men aged 70+; whether the total volume of activity is more important than pattern. METHODS AND RESULTS: Prospective population-based cohort study of men recruited from 24 UK General Practices in 1978-80. In 2010-12, 3137 survivors were invited to complete questionnaires and wear an Actigraph GT3x accelerometer for 7 days. PA intensity was categorised as sedentary, light and moderate to vigorous (MVPA). Men were followed up for Myocardial Infarction, stroke and heart failure (ICD9 410-414, 430-438 and 428) morbidity and mortality from 2010 to 12 to June 2016. Hazard Ratios (HRs) for incident Cardiovascular Disease (CVD) were estimated. 1528/3137 (49%) men had sufficient accelerometer data. 254 men with pre-existing CVD were excluded. Participants' mean age was 78.4 (range 71-92) years. After median 4.9 years follow-up, 122 first CVD events occurred in 1181 men (22.7/1000 person-years) with complete data. For each additional 30 min in sedentary behaviour, light PA,10 min in MVPA, or 1000 steps/day, HRs for CVD were 1.09(95%CI 1.00, 1.19), 0.94(0.85, 1.04), 0.88(0.81, 0.96) and 0.86(0.78 to 0.95) respectively, adjusted for measurement-related factors, socio-demographics, health behaviours and disability. HRs for accumulating 150 min/week MVPA in bouts ≥1 min and bouts ≥10 min were 0.47(0.32 to 0.69), and 0.49(0.25, 0.98). CONCLUSIONS: In older men, high volume of steps or MVPA rather than MVPA bouts was associated with reduced CVD risk
Pseudomyxoma Peritonei: A Need to Establish Evidence-Based Standard of Care—Is This the Right Trial?
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