Prevalence of recurrent aphthous stomatitis in a family medical office, Manzanillo, Cuban. A cross-sectional study

Introducción: La estomatitis aftosa recurrente, también conocida como úlceras aftosas o simplemente aftas, se considera la más común de las lesiones de la mucosa oral. Objetivo: Describir la prevalencia de la estomatitis aftosa recurrente. Método: Estudio descriptivo, transversal y prospectivo. Se evaluó a 847 pacientes que acudieron al Consultorio Médico de Familia N.o 28, Comunidad San Francisco, Manzanillo (Cuba), desde el 1 de julio de 2021 hasta el 30 de junio de 2022. Un investigador auxiliar, calibrado y capacitado, evaluó las siguientes variables: clasificación clínica de la estomatitis aftosa recurrente (aftosis menor, aftosis mayor, oaftosis herpetiforme), intensidad del dolor de la lesión, localización de la lesión, factores de riesgo (infección viral, infección bacteriana, alteraciones inmunológicas, alteraciones psicosomáticas, traumas bucales, alteraciones gastrointestinales, factores endocrinos, cuadros alérgicos, herencia, deficiencias hemáticas y nutricionales, tabaquismo), grupo etario, sexo, raza y tiempo de permanencia de la lesión. Resultados: La estomatitis aftosa recurrente presentó un 30,46%, con mayor frecuencia del grupo de edades 30-39 años (24,42%). La aftosis menor constituyó la de mayor frecuencia, con un 91,09%. El tiempo de permanencia de la lesión promedia 10 a 12 días (37,60%), la localización más frecuente corresponde a la zona de borde y punta de la lengua (32,94%) y la intensidad del dolor más representativa fue la leve (63,18%). La mayor frecuencia entre los factores de riesgo correspondió a las alteraciones psicosomáticas (100%). Conclusiones: La estomatitis aftosa recurrente tuvo una prevalencia mayor al 30%, con predominio del sexo femenino y adultos jóvenes. La aftosis menor y el tiempo de permanencia mayor de 10 días fueron las más frecuentes. La localización más común estuvo en la lengua y el fondo del surco vestibular, con posible existencia de una relación entre las partes móviles de la boca. El estrés es el principal factor de riesgo, agudizado por la COVID-19.Introduction: Recurrent Aphthous Stomatitis, also known as aphthous ulcers or simply aphthous, is considered the most common of oral mucosal lesions. Objective: To describe the prevalence of recurrent aphthous stomatitis. Methods: Descriptive, cross-sectional and prospective study. 847 patients who attended the Family Medical Office No. 28, San Francisco comunity, Manzanillo, from July 1, 2021 to June 30, 2022, Cuba, were evaluated. A calibrated and trained assistant investigator evaluated the following variables: Clinical classification of recurrent aphthous stomatitis (minor aphthosis, major aphthosis, or aphthosis herpetiformis), lesion pain intensity, lesion location, and risk factors (viral infection), bacterial infection, immunological alterations, psychosomatic alterations, oral trauma, gastrointestinal alterations, endocrine factors, allergic conditions, heredity, blood and nutritional deficiencies, smoking), age group, sex, race, and duration of the lesion. Results: Aphthous stomatitis occurred in 30.46%, with greater frequency in the age group 30 - 39 years (24.42%). Minor aphthosis was the most frequent with 91.09%. The duration of the lesion of 10 to 12 days predominated with 37.60%, the most frequent location corresponded to the edge and tip of the tongue with 32.94% and the most representative pain intensity was mild with a total of 63.18%. The highest frequency among the risk factors corresponded to psychosomatic alterations with 100%. Conclusions: Recurrent Aphthous Stomatitis had a prevalence greater than 30% with a predominance of the female sex and young adults. Minor Aphtosis and a stay time of more than 10 days were the most frequent. The most common location is the tongue and bottom of the vestibular sulcus with the possible existence of a relationship between the mobile parts of the mouth. Stress, the main risk factor, exacerbated by Covid-19

Ombligo en “cerradura de puerta” y hernia umbilical. Umbilicoplastia

RESUMEN Introducción: el ombligo es la única cicatriz considerada normal, es un componente esencial de la belleza. La paciente presenta una forma atípica del mismo acompañado de una hernia umbilical por lo que se decide realizar una umbilicoplastia basada en una técnica que dé una imagen estéticamente agradable. Caso clínico: paciente femenino, 17 años, llega a Consulta de Cirugía Plástica por presentar un ombligo que le provoca sentimientos de inferioridad y “complejo”, su forma se asemeja a una “cerradura de puerta” con una depresión a nivel de la piel por debajo de la cicatriz umbilical. Discusión: es necesario evaluar de forma integral el estado de salud. En el caso del ombligo acuden para cambiar el tamaño, forma, profundidad y posición para hacerlo ver estéticamente más agradable. Se realizó una incisión y cierre en “V-Y”, quedó de esta manera un ombligo con las características anatómicas normales, además de una forma y tamaño adecuados. Conclusiones: se logró un resultado estético adecuado. ABSTRACT Introduction: The navel is the only scar considered normal, being an essential component of beauty. The patient has a atypical form of the same accompanied by a umbilical hernia, is decided to make a umbilicoplasty based on a technical give an image aesthetically pleasant. Clinical case: Female patient, 17 years, comes to Plastic Surgery Ward to present a navel that causes feelings of inferiority and "complex", your shape resembles a "door lock" with a depression at the level of the skin below the umbilical scar. Discussion: It is necessary to assess comprehensively health status. In the case of navel come looking for resize, shape, depth and/or position to do see more aesthetically pleasant. Was carried out an incision and close in "V-Y" being in this way a navel with the anatomical features normal, along with a shape and size suitable. Conclusion: Was achieved a aesthetic result appropriate

Umbilicus in “door lock” and umbilical hernia. Umbilicoplasty

Introducción: el ombligo es la única cicatriz considerada normal, es un componenteesencial de la belleza. La paciente presenta una forma atípica del mismo acompañado deuna hernia umbilical por lo que se decide realizar una umbilicoplastia basada en una técnicaque dé una imagen estéticamente agradable.Caso clínico: paciente femenino, 17 años, llega a Consulta de Cirugía Plástica porpresentar un ombligo que le provoca sentimientos de inferioridad y “complejo”, su forma seasemeja a una “cerradura de puerta” con una depresión a nivel de la piel por debajo de lacicatriz umbilical.VERSION ON-LINE: ISSN 1028-4818Multimed. Revista Médica. Granma RPNS-18531032Discusión: es necesario evaluar de forma integral el estado de salud. En el caso delombligo acuden para cambiar el tamaño, forma, profundidad y posición para hacerlo verestéticamente más agradable. Se realizó una incisión y cierre en “V-Y”, quedó de estamanera un ombligo con las características anatómicas normales, además de una forma ytamaño adecuados.Conclusiones: se logró un resultado estético adecuado.Introduction: The navel is the only scar considered normal, being an essential componentof beauty. The patient has a atypical form of the same accompanied by a umbilical hernia, isdecided to make a umbilicoplasty based on a technical give an image aesthetically pleasant.Clinical case: Female patient, 17 years, comes to Plastic Surgery Ward to present a navelthat causes feelings of inferiority and "complex", your shape resembles a "door lock" with adepression at the level of the skin below the umbilical scar.Discussion: It is necessary to assess comprehensively health status. In the case of navelcome looking for resize, shape, depth and/or position to do see more aesthetically pleasant.Was carried out an incision and close in "V-Y" being in this way a navel with the anatomicalfeatures normal, along with a shape and size suitable.Conclusion: Was achieved a aesthetic result appropriate

Epidemiología de las quemaduras. Pacientes ingresados 2010

The burns are a vital experience, destructive and traumatic to the personal biography with functional and aesthetic evident sequels and with a great repercussion in the familiar, social and labor life of the patient. A descriptive, retrospective and longitudinal section study was made to the hospitalized patients at “Celia Sánchez Manduley” Hospital of Manzanillo, Granma in the year 2010, in the Aesthetic and Caumatology Caumatology Service. To achieve these objectives there were taken into consideration: age, sex, way of production, etiologic agent, life prognosis and the health condition at the time of the discharge. The ages between 15 and 59 prevailed as well as the male sex. The survival of the great burned was over the established prognosis. It is important to create health preventive programs to avoid burns, through the different mass media like the radio, television, papers, community, schools, and places of work and in the National Health System Centers.Las quemaduras son una experiencia vital traumática y destructiva para la biografía personal con secuelas funcionales y estéticas evidentes y con una enorme repercusión en la vida familiar, social y laboral del paciente. Se realizó un estudio descriptivo, retrospectivo y de corte longitudinal de los pacientes ingresados en el Hospital Provincial Clínico Quirúrgico Docente “Celia Sánchez Manduley” de Manzanillo, Granma en el año 2010, en el Servicio de Cirugía Plástica y Caumatología. Se evaluaron las variables de: edad, sexo, modo de producción, agente etiológico, pronóstico de vida y estado al egreso. Predominaron las edades entre 15 a 59 años y el sexo masculino. Los accidentes fueron el principal modo de producción y los líquidos calientes y/o hirvientes la principal causa, los pacientes con lesiones menos graves predominaron. La supervivencia de los grandes quemados se comportó por encima de los pronósticos establecidos. Se sugiere crear programas de prevención de salud efectivos para evitar las quemaduras utilizando los diferentes medios de difusión como la televisión, radio, prensa escrita, comunidad, centros de estudio, centros de trabajo y centros del Sistema Nacional de Salud

Physical activity therapeutic and prophylactic in the elderly

El mundo actual se enfrenta a disímiles desafíos entre los que se hallan los relacionados con la población. Una de las singularidades demográficas que más atención ha demandado en los últimos años es el progresivo envejecimiento poblacional. El adulto mayor, en cualquier escenario, juega un importante papel en la creación y desarrollo de la familia, él requiere de una atención integral que le permita gozar de una óptima salud. Se describe la importancia que tiene la actividad física terapéutica y profiláctica en el adulto mayor. Se cree que realizar deporte es algo que no corresponde a las personas mayores de 60 años, lo que responde a una imagen prejuiciosa de la vejez, además de ser una idea preconcebida de que las actividades deportivas pueden poner en peligro la salud del anciano. A pesar de los múltiples beneficios de la actividad física en el adulto mayor, es necesario antes de realizar cualquier tipo de ejercicio o actividad física, que se debe contar con la autorización del médico. La actividad física tanto profiláctica como terapéutica en el adulto mayor estimula el optimismo, la vitalidad y la voluntad, contribuye a la integración social, mejora calidad y disfrute de la vida, sobre todo mejora su salud.Today´s world faces dissimilar challenges between those related with the population. One of the singularities demographic more attention have demmanded in the last years is the progressive aging population. The elderly, at any scene, plays an important role in the creation and the family's development, he requires an integrated attention that allow old people enjoying an optimal health. It is believed that practicing sport is something that does not correspond to 60-years-elderly; which corresponds to a prejudiced image of old age, in addition to be a preconceived idea that sports activities can endanger the health of the elderly. Despite the multiple benefits of physical activity in the elderly, it is necessary to know that before any type of exercise or physical activity, elderly must have the authorization of the doctor. The physical activity so much prophylactic as therapeutics in the elderly stimulates the optimism, the vitality and will, it also contribute to the social integration, improving quality and enjoy of the life, especially improvement your health

Four-year epidemiological characterization of large burn patients at Celia Sánchez Manduley Surgical Hospital, 2015–2018

Introduction: A "large burn" patient is defined as a patient who suffers a burn of such magnitude that it carries a major risk of life, defined by different parameters. Burns are a national and worldwide public health problem due to the morbidity and mortality they cause. The objective of this study is to describe the epidemiological and clinical characteristics of hospitalized patients with large burns. Methods: A descriptive, retrospective and longitudinal study was carried out at the Plastic Surgery and Burn Service of the Celia Sánchez Manduley Surgical Hospital, Manzanillo - Granma, from January 2015 to December 2018, to understand the epidemiological characteristics of hospitalized large burn patients. Results: The largest number of hospitalizations (45 patients [35.16%]) occurred in 2018. There was a predominance of females (74 patients [57.81%]). Accidents were the most frequent cause of burns (71 patients [55.47%]). Severe large burn patients were the most frequently treated (48 [37.50%]). The highest number of cases occurred in the municipalities of Bayamo (40 cases [31.25%]) and Manzanillo (21 cases [16.41%]). Conclusion: The highest number of cases occurred in 2018, with a predominance of females between the age of 30-59 years. Accidents were the primary cause for burns, and the survival rate exceeded expectations. The municipalities with the most cases were Bayamo and Manzanillo

Aplicación didáctica de la canción popular en los estudios de Musciología. Recursos audiovisuales (televisión y radio) para el discente activo

Memoria ID-0149. Ayudas de la Universidad de alamanca para la innovación docente, curso 2015-2016

Compromising between European and US allergen immunotherapy schools: Discussions from GUIMIT, the Mexican immunotherapy guidelines

Background: Allergen immunotherapy (AIT) has a longstanding history and still remains the only disease-changing treatment for allergic rhinitis and asthma. Over the years 2 different schools have developed their strategies: the United States (US) and the European. Allergen extracts available in these regions are adapted to local practice. In other parts of the world, extracts from both regions and local ones are commercialized, as in Mexico. Here, local experts developed a national AIT guideline (GUIMIT 2019) searching for compromises between both schools. Methods: Using ADAPTE methodology for transculturizing guidelines and AGREE-II for evaluating guideline quality, GUIMIT selected 3 high-quality Main Reference Guidelines (MRGs): the European Academy of Allergy, Asthma and Immunology (EAACI) guideines, the S2k guideline of various German-speaking medical societies (2014), and the US Practice Parameters on Allergen Immunotherapy 2011. We formulated clinical questions and based responses on the fused evidence available in the MRGs, combined with local possibilities, patient's preference, and costs. We came across several issues on which the MRGs disagreed. These are presented here along with arguments of GUIMIT members to resolve them. GUIMIT (for a complete English version, see Supplementary data) concluded the following: Results: Related to the diagnosis of IgE-mediated respiratory allergy, apart from skin prick testing complementary tests (challenges, in vitro testing and molecular such as species-specific allergens) might be useful in selected cases to inform AIT composition. AIT is indicated in allergic rhinitis and suggested in allergic asthma (once controlled) and IgE-mediated atopic dermatitis. Concerning the correct subcutaneous AIT dose for compounding vials according to the US school: dosing tables and formula are given; up to 4 non-related allergens can be mixed, refraining from mixing high with low protease extracts. When using European extracts: the manufacturer's indications should be followed; in multi-allergic patients 2 simultaneous injections can be given (100% consensus); mixing is discouraged. In Mexico only allergoid tablets are available; based on doses used in all sublingual immunotherapy (SLIT) publications referenced in MRGs, GUIMIT suggests a probable effective dose related to subcutaneous immunotherapy (SCIT) might be: 50–200% of the monthly SCIT dose given daily, maximum mixing 4 allergens. Also, a table with practical suggestions on non-evidence-existing issues, developed with a simplified Delphi method, is added. Finally, dissemination and implementation of guidelines is briefly discussed, explaining how we used online tools for this in Mexico. Conclusions: Countries where European and American AIT extracts are available should adjust AIT according to which school is followed

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality