Isogrid design handbook

Handbook has been published which presents information needed for design of isogrid triangular integral-stiffened structures. It develops equations, methods, and graphs to handle wide variety of loadings, materials, and geometry. Handbook is divided into seven sections. Handbook may be used by marine and civil engineers and by students and designers without access to computers

Formation of X-ray emitting stationary shocks in magnetized protostellar jets

X-ray observations of protostellar jets show evidence of strong shocks heating the plasma up to temperatures of a few million degrees. In some cases, the shocked features appear to be stationary. They are interpreted as shock diamonds. We aim at investigating the physics that guides the formation of X-ray emitting stationary shocks in protostellar jets, the role of the magnetic field in determining the location, stability, and detectability in X-rays of these shocks, and the physical properties of the shocked plasma. We performed a set of 2.5-dimensional magnetohydrodynamic numerical simulations modelling supersonic jets ramming into a magnetized medium and explored different configurations of the magnetic field. The model takes into account the most relevant physical effects, namely thermal conduction and radiative losses. We compared the model results with observations, via the emission measure and the X-ray luminosity synthesized from the simulations. Our model explains the formation of X-ray emitting stationary shocks in a natural way. The magnetic field collimates the plasma at the base of the jet and forms there a magnetic nozzle. After an initial transient, the nozzle leads to the formation of a shock diamond at its exit which is stationary over the time covered by the simulations (~ 40 - 60 yr; comparable with time scales of the observations). The shock generates a point-like X-ray source located close to the base of the jet with luminosity comparable with that inferred from X-ray observations of protostellar jets. For the range of parameters explored, the evolution of the post-shock plasma is dominated by the radiative cooling, whereas the thermal conduction slightly affects the structure of the shock.Comment: Accepted for publication in Astronomy and Astrophysic

Chemical modification of bacterial cellulose for the development of an antibacterial wound dressing

Bacterial cellulose is a bacterially derived polymer with great potential for application in wound healing due to its innate properties such as high biocompatibility and biodegradability. In addition to this, it is naturally biosynthesized by bacteria as a hydrogel, which makes it an optimal substrate for the treatment of dry wounds, where additional moisture is required to facilitate the healing process. However, this polymer lacks antibacterial properties. As bacterial infections are becoming increasingly common and difficult to treat due to antimicrobial resistance, it is of crucial importance to develop strategies for the modification of cellulose to ensure protection against bacterial contamination. In this study, a green-chemistry approach was proposed for the functionalization of cellulose to introduce antibacterial functional groups. Two different active agents, namely glycidyl trimethylammonium chloride and glycidyl hexadecyl ether, were used for the covalent derivatization of the hydroxyl groups of glucose through a heterogeneous reaction in basic aqueous conditions. The modified material was chemically and mechanically characterized by solid-state techniques and rheological measurements. A biological assessment was then carried out both using bacterial cells and human keratinocytes. It was observed that the functionalization performed induced a reduction of approximately half of the bacterial population within 24 h of direct contact with Staphylococcus aureus subsp. aureus Rosenbach 6538PTM and Escherichia coli (Migula) Castellani and Chalmers ATCC® 8739TM (respectively, a reduction of 53% and 43% in the cell number was registered for the two strains). In parallel, cytotoxicity studies performed on keratinocytes (HaCaT cell line) showed cell viability in the range of 90 to 100% for up to 6 days of direct contact with both unmodified and modified samples. The morphology of the cells was also visually evaluated, and no significant difference was noted as compared to the control. Finally, the in vitro scratch assay evidenced good wound closure rates in the presence of the samples, with complete coverage of the scratched area after 5 days for both the modified cellulose and the positive control (i.e., keratinocytes growth medium). Overall, the modified hydrogel showed promising features, confirming its potential as an alternative substrate to develop a sustainable, antibacterial and biocompatible wound dressing

A tunable coupling scheme for implementing high-fidelity two-qubit gates

The prospect of computational hardware with quantum advantage relies critically on the quality of quantum gate operations. Imperfect two-qubit gates is a major bottleneck for achieving scalable quantum information processors. Here, we propose a generalizable and extensible scheme for a two-qubit coupler switch that controls the qubit-qubit coupling by modulating the coupler frequency. Two-qubit gate operations can be implemented by operating the coupler in the dispersive regime, which is non-invasive to the qubit states. We investigate the performance of the scheme by simulating a universal two-qubit gate on a superconducting quantum circuit, and find that errors from known parasitic effects are strongly suppressed. The scheme is compatible with existing high-coherence hardware, thereby promising a higher gate fidelity with current technologies

Fermi-LAT Observations of High- and Intermediate-Velocity Clouds: Tracing Cosmic Rays in the Halo of the Milky Way

It is widely accepted that cosmic rays (CRs) up to at least PeV energies are Galactic in origin. Accelerated particles are injected into the interstellar medium where they propagate to the farthest reaches of the Milky Way, including a surrounding halo. The composition of CRs coming to the solar system can be measured directly and has been used to infer the details of CR propagation that are extrapolated to the whole Galaxy. In contrast, indirect methods, such as observations of gamma-ray emission from CR interactions with interstellar gas, have been employed to directly probe the CR densities in distant locations throughout the Galactic plane. In this article we use 73 months of data from the Fermi Large Area Telescope in the energy range between 300 MeV and 10 GeV to search for gamma-ray emission produced by CR interactions in several high- and intermediate-velocity clouds located at up to ~ 7 kpc above the Galactic plane. We achieve the first detection of intermediate-velocity clouds in gamma rays and set upper limits on the emission from the remaining targets, thereby tracing the distribution of CR nuclei in the halo for the first time. We find that the gamma-ray emissivity per H atom decreases with increasing distance from the plane at 97.5% confidence level. This corroborates the notion that CRs at the relevant energies originate in the Galactic disk. The emissivity of the upper intermediate-velocity Arch hints at a 50% decline of CR densities within 2 kpc from the plane. We compare our results to predictions of CR propagation models.Comment: Accepted for publication in the Astrophysical Journa

Multi-wavelength constraints on cosmic-ray leptons in the Galaxy

Cosmic rays (CRs) interact with the gas, the radiation field and the magnetic field in the Milky Way, producing diffuse emission from radio to gamma rays. Observations of this diffuse emission and comparison with detailed predictions are powerful tools to unveil the CR properties and to study CR propagation. We present various GALPROP CR propagation scenarios based on current CR measurements. The predicted synchrotron emission is compared to radio surveys, and synchrotron temperature maps from WMAP and Planck, while the predicted interstellar gamma-ray emission is compared to Fermi-LAT observations. We show how multi-wavelength observations of the Galactic diffuse emission can be used to help constrain the CR lepton spectrum and propagation. Finally we discuss how radio and microwave data could be used in understanding the diffuse Galactic gamma-ray emission observed with Fermi-LAT, especially at low energies.Comment: 8 pages, 5 figures; in Proceedings of the 34th International Cosmic Ray Conference (ICRC 2015), The Hague (The Netherlands); Oral contributio

Classical Integrability of the Squashed Three-sphere, Warped AdS3 and Schroedinger Spacetime via T-Duality

We discuss the integrability of 2d non-linear sigma models with target space being the squashed three-sphere, warped anti-de Sitter space and the Schroedinger spacetime. These models can be obtained via T-duality from integrable models. We construct an infinite family of non-local conserved charges from the T-dual Lax currents, enhancing the symmetry of warped anti-de Sitter space and the Schroedinger spacetime to sl2(R)+sl2(R).Comment: 29 Pages, 3 appendices. Minor changes: added references, footnot

The Omega Deformation From String and M-Theory

We present a string theory construction of Omega-deformed four-dimensional gauge theories with generic values of \epsilon_1 and \epsilon_2. Our solution gives an explicit description of the geometry in the core of Nekrasov and Witten's realization of the instanton partition function, far from the asymptotic region of their background. This construction lifts naturally to M-theory and corresponds to an M5-brane wrapped on a Riemann surface with a selfdual flux. Via a 9-11 flip, we finally reinterpret the Omega deformation in terms of non-commutative geometry. Our solution generates all modified couplings of the \Omega-deformed gauge theory, and also yields a geometric origin for the quantum spectral curve of the associated quantum integrable system.Comment: LaTeX, 35 pages, 1 figure. Appendix on couplings of hypermultiplets in N=4 SYM adde

Segmentación automática de tejidos cerebrales en MRI multiespectrales mediante clasificación por mínima distancia euclídea

En este trabajo se presenta una estrategia simple para la segmentación automática de tejidos en imágenes de resonancia magnética multiespectrales basada principalmente en clasificación por mínima distancia euclídea. A partir de un conjunto de imágenes 3D en las modalidades T1, T1 con contraste de gadolinio, T2 y FLAIR y de sus segmentaciones de referencia se obtienen descriptores para cada tipo de tejido a través del centroide de cada clase, que son utilizados para clasificar nuevas imágenes de entrada. La clasificación resultante es sometida a un postprocesamiento que permite eliminar puntos espurios y aislados de modo de obtener mallas de superficie cerradas y compactas. El algoritmo fue evaluado sobre una base de datos de imágenes de resonancia sintéticas de cerebros con tumores de alto y bajo grado, obteniendo segmentaciones de alta calidad para los principales tejidos cerebrales y resultados comparables con los de otras propuestas para la segmentación de tumor y edema.Sociedad Argentina de Informática e Investigación Operativ

Segmentación automática de tejidos cerebrales en MRI multiespectrales mediante clasificación por mínima distancia euclídea

En este trabajo se presenta una estrategia simple para la segmentación automática de tejidos en imágenes de resonancia magnética multiespectrales basada principalmente en clasificación por mínima distancia euclídea. A partir de un conjunto de imágenes 3D en las modalidades T1, T1 con contraste de gadolinio, T2 y FLAIR y de sus segmentaciones de referencia se obtienen descriptores para cada tipo de tejido a través del centroide de cada clase, que son utilizados para clasificar nuevas imágenes de entrada. La clasificación resultante es sometida a un postprocesamiento que permite eliminar puntos espurios y aislados de modo de obtener mallas de superficie cerradas y compactas. El algoritmo fue evaluado sobre una base de datos de imágenes de resonancia sintéticas de cerebros con tumores de alto y bajo grado, obteniendo segmentaciones de alta calidad para los principales tejidos cerebrales y resultados comparables con los de otras propuestas para la segmentación de tumor y edema.Sociedad Argentina de Informática e Investigación Operativ