7,649 research outputs found
Quantum Harmonic Black Holes
Inspired by the recent conjecture that black holes are condensates of
gravitons, we investigate a simple model for the black hole degrees of freedom
that is consistent both from the point of view of Quantum mechanics and of
General Relativity. Since the two perspectives should "converge" into a unified
picture for small, Planck size, objects, we expect our construction is a useful
step for understanding the physics of microscopic, quantum black holes. In
particular, we show that a harmonically trapped condensate gives rise to two
horizons, whereas the extremal case (corresponding to a remnant with vanishing
Hawking temperature) naturally falls out of its spectrum.Comment: 7 pages, no figures. Clarifications and comments adde
Kalikow-type decomposition for multicolor infinite range particle systems
We consider a particle system on with real state space and
interactions of infinite range. Assuming that the rate of change is continuous
we obtain a Kalikow-type decomposition of the infinite range change rates as a
mixture of finite range change rates. Furthermore, if a high noise condition
holds, as an application of this decomposition, we design a feasible perfect
simulation algorithm to sample from the stationary process. Finally, the
perfect simulation scheme allows us to forge an algorithm to obtain an explicit
construction of a coupling attaining Ornstein's -distance for two
ordered Ising probability measures.Comment: Published in at http://dx.doi.org/10.1214/12-AAP882 the Annals of
Applied Probability (http://www.imstat.org/aap/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Unravelling the complex magnetic structure of multiferroic pyroxene NaFeGe2O6: A combined experimental and theoretical study
Magnetic order and the underlying magnetic model of the multiferroic pyroxene
NaFeGe2O6 are systematically investigated by neutron powder diffraction,
thermodynamic measurements, density-functional bandstructure calculations, and
Monte-Carlo simulations. Upon cooling, NaFeGe2O6 first reveals one-dimensional
spin-spin correlations in the paramagnetic state below about 50 K, revealed by
magnetic diffuse scattering. The sinusoidal spin-density wave with spins along
the a-direction sets in at 13 K, followed by the cycloidal configuration with
spins lying in the (ac) plane below 11.6 K. Microscopically, the strongest
magnetic coupling runs along the structural chains, J1 ' 12 K, which is likely
related to the one-dimensional spin-spin correlations. The interchain couplings
J2 ' 3:8K and J3 ' 2:1K are energetically well balanced and compete, thus
giving rise to the incommensurate order in sharp contrast to other
transition-metal pyroxenes, where one type of the interchain couplings
prevails. The magnetic model of NaFeGe2O6 is further completed by the weak
single-ion anisotropy along the a-direction. Our results resolve the earlier
controversies regarding the magnetic order in NaFeGe2O6 and establish relevant
symmetries of the magnetic structures. These results, combined with symmetry
analysis, enable us to identify the possible mechanisms of the magnetoelectric
coupling in this compound. We also elucidate microscopic conditions for the
formation of incommensurate magnetic order in pyroxenes.Comment: 10 pages 10 figures, PRB(accepted
A variable delay integrated receiver for differential phase-shift keying optical transmission systems
An integrated variable delay receiver for DPSK optical transmission systems is presented. The device is realized in silicon-on-insulator technology and can be used to detect DPSK signals at any bit-rates between 10 and 15 Gbit/s
Diabetes and aging: a different phenotypic commitment of circulating and resident stem cells?
Investigation of Hamamatsu H8500 phototubes as single photon detectors
We have investigated the response of a significant sample of Hamamatsu H8500
MultiAnode PhotoMultiplier Tubes (MAPMTs) as single photon detectors, in view
of their use in a ring imaging Cherenkov counter for the CLAS12 spectrometer at
the Thomas Jefferson National Accelerator Facility. For this, a laser working
at 407.2nm wavelength was employed. The sample is divided equally into standard
window type, with a spectral response in the visible light region, and
UV-enhanced window type MAPMTs. The studies confirm the suitability of these
MAPMTs for single photon detection in such a Cherenkov imaging application
On the Unruh effect in de Sitter space
We give an interpretation of the temperature in de Sitter universe in terms
of a dynamical Unruh effect associated with the Hubble sphere. As with the
quantum noise perceived by a uniformly accelerated observer in static
space-times, observers endowed with a proper motion can in principle detect the
effect. In particular, we study a "Kodama observer" as a two-field Unruh
detector for which we show the effect is approximately thermal. We also
estimate the back-reaction of the emitted radiation and find trajectories
associated with the Kodama vector fields are stable.Comment: 8 pages; corrected typos; sections structure revise
A microscopic approach to critical phenomena at interfaces: an application to complete wetting in the Ising model
We study how the formalism of the Hierarchical Reference Theory (HRT) can be
extended to inhomogeneous systems. HRT is a liquid state theory which
implements the basic ideas of Wilson momentum shell renormalization group (RG)
to microscopic Hamiltonians. In the case of homogeneous systems, HRT provides
accurate results even in the critical region, where it reproduces scaling and
non-classical critical exponents. We applied the HRT to study wetting critical
phenomena in a planar geometry. Our formalism avoids the explicit definition of
effective surface Hamiltonians but leads, close to the wetting transition, to
the same renormalization group equation already studied by RG techiques.
However, HRT also provides information on the non universal quantities because
it does not require any preliminary coarse graining procedure. A simple
approximation to the infinite HRT set of equations is discussed. The HRT
evolution equation for the surface free energy is numerically integrated in a
semi-infinite three-dimensional Ising model and the complete wetting phase
transition is analyzed. A renormalization of the adsorption critical amplitude
and of the wetting parameter is observed. Our results are compared to available
Monte Carlo simulations.Comment: To be published in Phy. Rev.
An observational and numerical case study of a flash sea storm over the Gulf of Genoa
International audienceDuring the night between the 8 and 9 December 2006 the seawall of the Savona harbour (Liguria Region in north west of Italy) was overtopped by waves. In this work the "Savona flash sea storm" has been studied by analyzing the data recorded by meteo-marine observing stations and the data produced by high resolution meteo-marine numerical models. The data show that, due to the presence of a fast moving low pressure system, the event was characterized by a rapid transition and interaction between two different regimes of winds and related sea states. The results of the study suggest that the most damaging dynamics of the event could be correlated to a bi-modal structure of the wave spectrum. Based on this the authors suggest that a deeper study of the spectral structure of sea storms could lead to define new operational forecasting tools for the preventive evaluation of sea storms damaging potential
In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
Aberrant Hedgehog (Hh)/glioma-associated oncogene (GLI) signaling has
been implicated in cancer progression. Here, we analyzed GLI1, Sonic Hedgehog
(Shh) and NF-κB expression in 51 breast cancer (ductal carcinoma) tissues using
immunohistochemistry. We found a positive correlation between nuclear GLI1
expression and tumor grade in ductal carcinoma cases. Cytoplasmic Shh staining
significantly correlated with a lower tumor grade. Next, the in vitro effects of two
Hh signaling pathway inhibitors on breast cancer cell lines were evaluated using the
Smoothened (SMO) antagonist GDC-0449 and the direct GLI1 inhibitor GANT-61.
GDC-0449 and GANT-61 exhibited the following effects: a) inhibited breast cancer
cell survival; b) induced apoptosis; c) inhibited Hh pathway activity by decreasing
the mRNA expression levels of GLI1 and Ptch and inhibiting the nuclear translocation
of GLI1; d) increased/decreased EGFR and ErbB2 protein expression, reduced p21-
Ras and ERK1/ERK2 MAPK activities and inhibited AKT activation; and e) decreased
the nuclear translocation of NF-κB. However, GANT-61 exerted these effects more
effectively than GDC-0449. The in vivo antitumor activities of GDC-0449 and GANT-
61 were analyzed in BALB/c mice that were subcutaneously inoculated with mouse
breast cancer (TUBO) cells. GDC-0449 and GANT-61 suppressed tumor growth of
TUBO cells in BALB/c mice to different extents. These findings suggest that targeting
the Hh pathway using antagonists that act downstream of SMO is a more efficient
strategy than using antagonists that act upstream of SMO for interrupting Hh signaling
in breast cancer
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