Clouds, photolysis and regional tropospheric ozone budgets.

We use a three-dimensional chemical transport model to examine the shortwave radiative effects of clouds on the tropospheric ozone budget. In addition to looking at changes in global concentrations as previous studies have done, we examine changes in ozone chemical production and loss caused by clouds and how these vary in different parts of the troposphere. On a global scale, we find that clouds have a modest effect on ozone chemistry, but on a regional scale their role is much more significant, with the size of the response dependent on the region. The largest averaged changes in chemical budgets (±10–14%) are found in the marine troposphere, where cloud optical depths are high. We demonstrate that cloud effects are small on average in the middle troposphere because this is a transition region between reduction and enhancement in photolysis rates. We show that increases in boundary layer ozone due to clouds are driven by large-scale changes in downward ozone transport from higher in the troposphere rather than by decreases in in-situ ozone chemical loss rates. Increases in upper tropospheric ozone are caused by higher production rates due to backscattering of radiation and consequent increases in photolysis rates, mainly J(NO2). The global radiative effect of clouds on isoprene, through decreases of OH in the lower troposphere, is stronger than on ozone. Tropospheric isoprene lifetime increases by 7% when taking clouds into account. We compare the importance of clouds in contributing to uncertainties in the global ozone budget with the role of other radiatively-important factors. The budget is most sensitive to the overhead ozone column, while surface albedo and clouds have smaller effects. However, uncertainty in representing the spatial distribution of clouds may lead to a large sensitivity of the ozone budget components on regional scales

A CFH12k lensing survey of X-ray luminous galaxy clusters. II. Weak lensing analysis and global correlations

Aims. We present a wide-field multi-color survey of a homogeneous sample of eleven clusters of galaxies for which we measure total masses and mass distributions from weak lensing. This sample, spanning a small range in both X-ray luminosity and redshift, is ideally suited to determining the normalisation of scaling relations between X-ray properties of clusters and their masses (the M − T_X and the M − L_X relations) and also estimating the scatter in these relations at a fixed luminosity. Methods. The eleven clusters in our sample are all X-ray luminous and span a narrow redshift range at z = 0.21 ± 0.04. The weak lensing analysis of the sample is based on ground-based wide-field imaging obtained with the CFH12k camera on CFHT. We use the methodology developed and applied previously on the massive cluster Abell 1689. A Bayesian method, implemented in the Im2shape software, is used to fit the shape parameters of the faint background galaxies and to correct for PSF smearing. A multi-color selection of the background galaxies is applied to retrieve the weak lensing signal, resulting in a background density of sources of ~10 galaxies per square arc minute. With the present data, shear profiles are measured in all clusters out to at least 2 Mpc (more than 15 from the center) with high confidence. The radial shear profiles are fitted with different parametric mass profiles and the virial mass M_(200) is estimated for each cluster and then compared to other physical properties. Results. Scaling relations between mass and optical luminosity indicate an increase of the M/L ratio with luminosity (M/L ∝ L^(0.8)) and a LX−M_(200) relation scaling as L_X ∝ M^(0.83±0.11)_(200) while the normalization of the M_(200) ∝ T^(3/2)_X relation is close to the one expected from hydrodynamical simulations of cluster formation as well as previous X-ray analyses. We suggest that the dispersion in the M_(200) − T_X and M_(200) − L_X relations reflects the different merging and dynamical histories for clusters of similar X-ray luminosities and intrinsic variations in their measured masses. Improved statistics of clusters over a wider mass range are required for a better control of the intrinsic scatter in scaling relations

Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2.

Poly(ADP-ribose) polymerase-1 (PARP-1) has become an important pharmacological target in the treatment of cancer due to its cellular role as a 'DNA-strand break sensor', which leads in part to resistance to some existing chemo- and radiological treatments. Inhibitors have now been developed which prevent PARP-1 from synthesizing poly(ADP-ribose) in response to DNA-breaks and potentiate the cytotoxicity of DNA damaging agents. However, with the recent discoveries of PARP-2, which has a similar DNA-damage dependent catalytic activity, and additional members containing the 'PARP catalytic' signature, the isoform selectivity and resultant pharmacological effects of existing inhibitors are brought into question. We present here the crystal structure of the catalytic fragment of murine PARP-2, at 2.8 A resolution, and compare this to the catalytic fragment of PARP-1, with an emphasis on providing a possible framework for rational drug design in order to develop future isoform-specific inhibitors

L1-determined ideals in group algebras of exponential Lie groups

A locally compact group $G$ is said to be $\ast$-regular if the natural map \Psi:\Prim C^\ast(G)\to\Prim_{\ast} L^1(G) is a homeomorphism with respect to the Jacobson topologies on the primitive ideal spaces \Prim C^\ast(G) and \Prim_{\ast} L^1(G). In 1980 J. Boidol characterized the $\ast$-regular ones among all exponential Lie groups by a purely algebraic condition. In this article we introduce the notion of $L^1$-determined ideals in order to discuss the weaker property of primitive $\ast$-regularity. We give two sufficient criteria for closed ideals $I$ of $C^\ast(G)$ to be $L^1$-determined. Herefrom we deduce a strategy to prove that a given exponential Lie group is primitive $\ast$-regular. The author proved in his thesis that all exponential Lie groups of dimension $\le 7$ have this property. So far no counter-example is known. Here we discuss the example $G=B_5$, the only critical one in dimension $\le 5$

Explicit solution of the linearized Einstein equations in TT gauge for all multipoles

We write out the explicit form of the metric for a linearized gravitational wave in the transverse-traceless gauge for any multipole, thus generalizing the well-known quadrupole solution of Teukolsky. The solution is derived using the generalized Regge-Wheeler-Zerilli formalism developed by Sarbach and Tiglio.Comment: 9 pages. Minor corrections, updated references. Final version to appear in Class. Quantum Gra

Oscillatory Modes of a Prominence-PCTR-Corona Slab Model

Oscillations of magnetic structures in the solar corona have often been interpreted in terms of magnetohydrodynamic waves. We study the adiabatic magnetoacoustic modes of a prominence plasma slab with a uniform longitudinal magnetic field, surrounded by a prominence-corona transition region (PCTR) and a coronal medium. Considering linear small-amplitude oscillations, the dispersion relation for the magnetoacoustic slow and fast modes is deduced assuming evanescent-like perturbations in the coronal medium. In the system without PCTR, a classification of the oscillatory modes according to the polarisation of their eigenfunctions is made in order to distinguish modes with fast-like or slow-like properties. Internal and external slow modes are governed by the prominence and coronal properties respectively, and fast modes are mostly dominated by prominence conditions for the observed wavelengths. In addition, the inclusion of an isothermal PCTR does not substantially influence the mode frequencies, but new solutions (PCTR slow modes) are present.Comment: Accepted for publication in Solar Physic

The motivating operation and negatively reinforced problem behavior. A systematic review.

The concept of motivational operations exerts an increasing influence on the understanding and assessment of problem behavior in people with intellectual and developmental disability. In this systematic review of 59 methodologically robust studies of the influence of motivational operations in negative reinforcement paradigms in this population, we identify themes related to situational and biological variables that have implications for assessment, intervention, and further research. There is now good evidence that motivational operations of differing origins influence negatively reinforced problem behavior, and that these might be subject to manipulation to facilitate favorable outcomes. There is also good evidence that some biological variables warrant consideration in assessment procedures as they predispose the person's behavior to be influenced by specific motivational operations. The implications for assessment and intervention are made explicit with reference to variables that are open to manipulation or that require further research and conceptualization within causal models

Superconducting Diamond on Silicon Nitride for Device Applications

Chemical vapour deposition (CVD) grown nanocrystalline diamond is an attractive material for the fabrication of devices. For some device architectures, optimisation of its growth on silicon nitride is essential. Here, the effects of three pre-growth surface treatments, often employed as cleaning methods of silicon nitride, were investigated. Such treatments provide control over the surface charge of the substrate through modification of the surface functionality, allowing for the optimisation of electrostatic diamond seeding densities. Zeta potential measurements and X-ray photoelectron spectroscopy (XPS) were used to analyse the silicon nitride surface following each treatment. Exposing silicon nitride to an oxygen plasma offered optimal surface conditions for the electrostatic self-assembly of a hydrogen-terminated diamond nanoparticle monolayer. The subsequent growth of boron-doped nanocrystalline diamond thin films on modified silicon nitride substrates under CVD conditions produced coalesced films for oxygen plasma and solvent treatments, whilst pin-holing of the diamond film was observed following RCA-1 treatment. The sharpest superconducting transition was observed for diamond grown on oxygen plasma treated silicon nitride, demonstrating it to be of the least structural disorder. Modifications to the substrate surface optimise the seeding and growth processes for the fabrication of diamond on silicon nitride devices

Star Formation in the Northern Cloud Complex of NGC 2264

We have made continuum and spectral line observations of several outflow sources in the Mon OB1 dark cloud (NGC 2264) using the Heinrich Hertz Telescope (HHT) and ARO 12m millimeter-wave telescope. This study explores the kinematics and outflow energetics of the young stellar systems observed and assesses the impact star formation is having on the surrounding cloud environment. Our data set incorporates 12CO(3-2), 13CO(3-2), and 12CO(1-0) observations of outflows associated with the sources IRAS 06382+1017 and IRAS 06381+1039, known as IRAS 25 and 27, respectively, in the northern cloud complex. Complementary 870 micron continuum maps were made with the HHT 19 channel bolometer array. Our results indicate that there is a weak (approximately less than 0.5%) coupling between outflow kinetic energy and turbulent energy of the cloud. An analysis of the energy balance in the IRAS 25 and 27 cores suggests they are maintaining their dynamical integrity except where outflowing material directly interacts with the core, such as along the outflow axes.Comment: 28 pages including 6 figures, to be published in ApJ 01 July 2006, v645, 1 issu

Rigorous confidence intervals for critical probabilities

We use the method of Balister, Bollobas and Walters to give rigorous 99.9999% confidence intervals for the critical probabilities for site and bond percolation on the 11 Archimedean lattices. In our computer calculations, the emphasis is on simplicity and ease of verification, rather than obtaining the best possible results. Nevertheless, we obtain intervals of width at most 0.0005 in all cases