11,295 research outputs found

    Effects of replacing soybean meal with xylose-treated soybean meal on performance of nursing Awassi ewes and fattening lambs

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    Two experiments were conducted to evaluate the effect of replacing soybean meal with xylose-treated soybean meal (soypass meal; SPM) on performance of nursing Awassi ewes and fattening lambs. In Experiment 1, lasting for eight weeks, 39 Awassi ewes and their lambs were randomly assigned to three diets. Diets were formulated by replacing soybean meal from the basal diet (CON-SBM; n=13) with 50% (50% SPM; n=13) and 100% (100% SPM; n=13) SPM. Initial and final weights of the ewes were not different (P>0.55) among diets. Total gain and average daily gain (ADG) of lambs were similar (P=0.44) among diets. Ewes fed the CON-SBM diet tended (P<0.09) to have lower milk yields than those fed the 50% SPM and 100% SPM diets. No differences (P>0.38) in milk component percentages among diets were observed. In Experiment 2, lasting for 63 days, twenty weaned lambs were used to determine the effects of replacing soybean meal with SPM on growth performance. Diets were either soybean meal (SBM; n=10) or SPM (SPM; n=10). Nutrient intake and digestibility were not different between diets. However, rumen undegradable protein intake was greater (P<0.05) for the SPM diet than for the SBM diet. Final body weight, ADG and the feed conversion ratio were similar (P>0.05) between the diets. Results suggest that replacement of soybean meal with soypass meal is not likely to produce any production benefits in nursing Awassi ewes and fattening lambs except for the slight improvement of milk yield

    Sea Level Rise für the U.S. West Coast

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    Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

    Dispelling the myth of robotic efficiency: why human space exploration will tell us more about the Solar System than will robotic exploration alone

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    There is a widely held view in the astronomical community that unmanned robotic space vehicles are, and will always be, more efficient explorers of planetary surfaces than astronauts (e.g. Coates, 2001; Clements 2009; Rees 2011). Partly this is due to a common assumption that robotic exploration is cheaper than human exploration (although, as we shall see, this isn't necessarily true if like is compared with like), and partly from the expectation that continued developments in technology will relentlessly increase the capability, and reduce the size and cost, of robotic missions to the point that human exploration will not be able to compete. I will argue below that the experience of human exploration during the Apollo missions, more recent field analogue studies, and trends in robotic space exploration actually all point to exactly the opposite conclusion.Comment: 12 pages; 5 figures. Published, with minor modifications, in Astronomy and Geophysics, Vol. 53, pp. 2.22-2.26, 201

    Exposure to Secondhand Smoke and Arrhythmogenic Cardiac Alternans in a Mouse Model.

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    BackgroundEpidemiological evidence suggests that a majority of deaths attributed to secondhand smoke (SHS) exposure are cardiovascular related. However, to our knowledge, the impact of SHS on cardiac electrophysiology, [Formula: see text] handling, and arrhythmia risk has not been studied.ObjectivesThe purpose of this study was to investigate the impact of an environmentally relevant concentration of SHS on cardiac electrophysiology and indicators of arrhythmia.MethodsMale C57BL/6 mice were exposed to SHS [total suspended particles (THS): [Formula: see text], nicotine: [Formula: see text], carbon monoxide: [Formula: see text], or filtered air (FA) for 4, 8, or 12 wk ([Formula: see text]]. Hearts were excised and Langendorff perfused for dual optical mapping with voltage- and [Formula: see text]-sensitive dyes.ResultsAt slow pacing rates, SHS exposure did not alter baseline electrophysiological parameters. With increasing pacing frequency, action potential duration (APD), and intracellular [Formula: see text] alternans magnitude progressively increased in all groups. At 4 and 8 wk, there were no statistical differences in APD or [Formula: see text] alternans magnitude between SHS and FA groups. At 12 wk, both APD and [Formula: see text] alternans magnitude were significantly increased in the SHS compared to FA group ([Formula: see text]). SHS exposure did not impact the time constant of [Formula: see text] transient decay ([Formula: see text]) at any exposure time point. At 12 wk exposure, the recovery of [Formula: see text] transient amplitude with premature stimuli was slightly (but nonsignificantly) delayed in SHS compared to FA hearts, suggesting that [Formula: see text] release via ryanodine receptors may be impaired.ConclusionsIn male mice, chronic exposure to SHS at levels relevant to social situations in humans increased their susceptibility to cardiac alternans, a known precursor to ventricular arrhythmia. https://doi.org/10.1289/EHP3664

    Variaciones en el desarrollo, influencias socioculturales, y dificultades en el aprendizaje de las matemáticas

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    Es sabido que la mayoría de los niños entran en la escuela con conocimientos y recursos fundacionales para su aprendizaje matemático. Sin embargo, esta no es la historia completa. Resultados de investigaciones revelan enormes diferencias en los niveles de competencia matemática de los niños pequeños, y estas diferencias parecen ser más acusadas en los Estados Unidos que en algunos otros países (por ejemplo, China) (Starkey y Klein, 2008). En este artículo se describen los tipos de diferencias que se dan y se ofrece una revisión sobre lo que se sabe acerca de la naturaleza y las fuentes de las variaciones en el desarrollo entre los niños

    Fundamentos cognitivos para la iniciación en el aprendizaje de las matemáticas

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    En este artículo, sobre fundamentos cognitivos para la iniciación en el aprendizaje de las matemáticas, se realiza una revisión de investigaciones sobre el aprendizaje de las matemáticas en educación infantil. Esta revisión está estructurada según los siguientes apartados: Evidencias sobre la comprensión temprana del número, desarrollo del pensamiento espacial y la geometría, desarrollo de la medición, y regulación de la conducta y la atención

    Contenido matemático fundacional para el aprendizaje en los primeros años

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    En este capítulo se describe el contenido matemático fundacional accesible para niñas y niños pequeños. El foco en este capítulo está puesto en las propias ideas matemáticas, más que en la enseñanza y el aprendizaje de las mismas. Estas ideas matemáticas se dan por sentadas por los adultos, pero son sorprendentemente profundas y complejas. Hay dos áreas fundamentales en las matemáticas para la primera infancia: (1) el número y (2) la geometría y la medición, tal como identifican los Focos Currículares del NCTM y subrraya este comité. También hay importantes procesos de razonamiento matemático en que los niños deben implicarse. Este capítulo también describe algunas de las conexiones más importantes de las matemáticas infantiles con las matemáticas posteriores

    Whole-Blood Taurine Concentrations in Cats With Intestinal Disease

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    BackgroundIncreased delivery of taurine-conjugated bile acids to the distal bowel can lead to dysbiosis resulting in colitis in mouse models of inflammatory bowel disease. A similar situation also could occur in cats with intestinal disease and might therefore result in decreased whole-body taurine concentration.Hypothesis/objectivesTo determine whether whole-blood taurine concentrations are decreased at the time of diagnosis in cats with intestinal disease and to correlate concentrations with clinical and laboratory variables.AnimalsTwenty-one cats with chronic inflammatory enteropathy and 7 cats with intestinal neoplasia from the University of Bristol.MethodsCats that had undergone a thorough investigation consisting of a CBC, serum biochemistry, serum cobalamin and folate concentrations, transabdominal ultrasound examination and histopathology of intestinal biopsy specimens, as well as additional testing if indicated, were included. Whole-blood from these cats collected at the time of histologic diagnosis and stored in ethylenediaminetetraacetic acid was retrospectively analyzed for taurine with an automated high-performance liquid chromatography amino acid analyzer.ResultsAlthough whole-blood taurine concentrations remained within the reference range, those cats with predominantly large intestinal clinical signs had significantly lower concentrations than did cats with small intestinal and mixed bowel clinical signs (P = 0.033) and this difference also was significant when assessed only in cats with chronic inflammatory enteropathy (P = 0.019).Conclusions and clinical importanceAdditional studies are needed to determine whether large intestinal signs in cats with chronic inflammatory enteropathy are caused by alterations in the microbiota arising as a consequence of increased delivery of taurine-conjugated bile acids
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