49 research outputs found
Density functional calculations of the electronic structure and magnetic properties of the hydrocarbon K3picene superconductor near the metal-insulator transition
We have investigated the electronic structures and magnetic properties of of
K3picene, which is a first hydrocarbon superconductor with high transition
temperature T_c=18K. We have shown that the metal-insulator transition (MIT) is
driven in K3picene by 5% volume enhancement with a formation of local magnetic
moment. Active bands for superconductivity near the Fermi level E_F are found
to have hybridized character of LUMO and LUMO+1 picene molecular orbitals.
Fermi surfaces of K3picene manifest neither prominent nesting feature nor
marked two-dimensional behavior. By estimating the ratio of the Coulomb
interaction U and the band width W of the active bands near E_F, U/W, we have
demonstrated that K3picene is located in the vicinity of the Mott transition.Comment: 5 pages, 5 figure
Rethinking Session Variability: Leveraging Session Embeddings for Session Robustness in Speaker Verification
In the field of speaker verification, session or channel variability poses a
significant challenge. While many contemporary methods aim to disentangle
session information from speaker embeddings, we introduce a novel approach
using an additional embedding to represent the session information. This is
achieved by training an auxiliary network appended to the speaker embedding
extractor which remains fixed in this training process. This results in two
similarity scores: one for the speakers information and one for the session
information. The latter score acts as a compensator for the former that might
be skewed due to session variations. Our extensive experiments demonstrate that
session information can be effectively compensated without retraining of the
embedding extractor
Cytosolic Internalization of Anti-DNA Antibodies by Human Monocytes Induces Production of Pro-inflammatory Cytokines Independently of the Tripartite Motif-Containing 21 (TRIM21)-Mediated Pathway
Anti-DNA autoantibodies are a hallmark of systemic lupus erythematosus (SLE). A subset of anti-DNA IgG autoantibodies is cell-internalizable; thus they can enter living cells in the form of free IgG. However, the contribution made by the Fc region of internalized free-form IgG to the cytokine response has not been studied, despite the recent discovery of tripartite motif-containing 21 (TRIM21), a cytosolic Fc receptor involved in immune signaling. This study used an internalizable IgG anti-DNA antibody (3D8) to examine the cytokine responses of human monocytes to the Fc region of cytosolic free IgG. Internalization of 3D8 IgG and a 3D8 single-chain variable fragment-Fc (scFv-Fc) induced production of IL-8 and TNF-α via activation of NF-κB. By contrast, a 3D8 scFv (comprising variable domains alone) did not. This suggests Fc-dependent cytokine signaling. A 3D8 IgG-N434D mutant that is not recognized by TRIM21 induced greater production of cytokines than 3D8 IgG. Moreover the amounts of cytokines induced by 3D8 IgG in TRIM21-knockdown THP-1 cells were higher than those in control cells, indicating that cytokine signaling is not mediated by TRIM21. The results suggest the existence of a novel Fc-dependent signaling pathway that is activated upon internalization of IgG antibodies by human monocytes
Encoder-decoder multimodal speaker change detection
The task of speaker change detection (SCD), which detects points where
speakers change in an input, is essential for several applications. Several
studies solved the SCD task using audio inputs only and have shown limited
performance. Recently, multimodal SCD (MMSCD) models, which utilise text
modality in addition to audio, have shown improved performance. In this study,
the proposed model are built upon two main proposals, a novel mechanism for
modality fusion and the adoption of a encoder-decoder architecture. Different
to previous MMSCD works that extract speaker embeddings from extremely short
audio segments, aligned to a single word, we use a speaker embedding extracted
from 1.5s. A transformer decoder layer further improves the performance of an
encoder-only MMSCD model. The proposed model achieves state-of-the-art results
among studies that report SCD performance and is also on par with recent work
that combines SCD with automatic speech recognition via human transcription.Comment: 5 pages, accepted for presentation at INTERSPEECH 202
Analysis Of Cosmic Ray Data Taken During The Commissioning Of The New ALICE Inner Tracking System
In this project, cosmic data taken with the first fully assembled innermost half-layer of the new Inner Tracking System of ALICE is analyzed. The analysis comprises the determination of cluster parameters, i.e. number of pixels in a cluster, shape of cluster for different biasing conditions. Furthermore, the impact of different bias settings onto the fake-hit rate is analyzed