Electrical Resistivity Studies in the Kansas River Valley

In order to investigate the application of resistivity methods to groundwater studies in eastern Kansas, electrical resistivity depth profiles were run in the Kansas River Valley at localities where geologic conditions were known. The results of this survey show that the depth to water table and bedrock can be determined in the Kansas River Valley. To a less certain degree interpretations can also be made concerning lithology and type of water contained in the alluvial sediments

Progress Report of the Kansas Basement Rocks Committee and Additional Precambrian Wells

The Kansas Basement Rocks Committee is actively collecting data pertaining to Precambrian rocks of Kansas. An additional 84 wells known to encounter the Precambrian bring the total number of known Precambrian tests in Kansas to about 2,200 as of December 31, 1961. A generalized configuration map of the surface of Precambrian rocks shows major post-Mississippian structural features in the state. Potassium-argon age dates for five samples range from 1165 to 1460 million years

Review of Geophysical Activity in Kansas Through 1956

A complete bibliography of 52 published geophysical papers on Kansas is presented along with a brief description of each. The subjects include magnetic, gravity, electrical, and seismic work, but exclude bore-hole investigations and geochemical studies. A review of geophysical exploration in the state for the past 20 years also is presented. Cross reference to the bibliography by subject and county is given

Review of Geophysical Activity in Kansas Through 1956

A complete bibliography of 52 published geophysical papers on Kansas is presented along with a brief description of each. The subjects include magnetic, gravity, electrical, and seismic work, but exclude bore-hole investigations and geochemical studies. A review of geophysical exploration in the state for the past 20 years also is presented. Cross reference to the bibliography by subject and county is given

Progress Report of the Kansas Basement Rocks Committee and Additional Precambrian Wells

The Kansas Basement Rocks Committee is actively collecting data pertaining to Precambrian rocks of Kansas. An additional 84 wells known to encounter the Precambrian bring the total number of known Precambrian tests in Kansas to about 2,200 as of December 31, 1961. A generalized configuration map of the surface of Precambrian rocks shows major post-Mississippian structural features in the state. Potassium-argon age dates for five samples range from 1165 to 1460 million years

Reconstructing Late Cenozoic Stream Gradients from High-Level Chert Gravels in Central Eastern Kansas

Interpreting the evolution of Kansas' landscape east of the Flint Hills provides major challenges. In the Neogene (late Tertiary) and perhaps part of the Pleistocene, streams transported a variety of sedimentary materials, including chert gravels derived from the Flint Hills. Gentle intermittent uplift stimulated the stream system to cut down, locally removing and reworking the gravels to create stream-terrace deposits that consist mostly of chert pebbles, which now lie well above the floodplains of modern streams. By correlating the elevations of these gravels, the gradients of the trunk streams that deposited them can be reconstructed. Interestingly, these ancient streams flowed southeast at a little more than a foot per mile (0.2 m/km), roughly the same as the gradient of the trunk streams in the region today. The evolving landscape in eastern Kansas also has been strongly influenced by an extensive network of fractures that is widespread in the midcontinent region and may be worldwide in extent. In northeastern Kansas, glaciation during the Pleistocene disrupted the southeasterly drainage and established the present location of the Kansas River. South of the Kansas River and its immediate tributaries, however, the general southeasterly drainage has been preserved. We have made use of the wealth of topographic-elevation data now available in digital form known as DEMs or digital elevation models. Coupled with GIS procedures, the DEMs helped link the mapped distribution of chert gravels with hypothetical fitted surfaces that represent ancient stream gradients. Furthermore, DEM data placed in shaded-relief map form emphasize the influence of fractures in evolution of the drainage system

A Novel Ecdysone Receptor Mediates Steroid-Regulated Developmental Events during the Mid-Third Instar of Drosophila

The larval salivary gland of Drosophila melanogaster synthesizes and secretes glue glycoproteins that cement developing animals to a solid surface during metamorphosis. The steroid hormone 20-hydroxyecdysone (20E) is an essential signaling molecule that modulates most of the physiological functions of the larval gland. At the end of larval development, it is known that 20E—signaling through a nuclear receptor heterodimer consisting of EcR and USP—induces the early and late puffing cascade of the polytene chromosomes and causes the exocytosis of stored glue granules into the lumen of the gland. It has also been reported that an earlier pulse of hormone induces the temporally and spatially specific transcriptional activation of the glue genes; however, the receptor responsible for triggering this response has not been characterized. Here we show that the coordinated expression of the glue genes midway through the third instar is mediated by 20E acting to induce genes of the Broad Complex (BRC) through a receptor that is not an EcR/USP heterodimer. This result is novel because it demonstrates for the first time that at least some 20E-mediated, mid-larval, developmental responses are controlled by an uncharacterized receptor that does not contain an RXR-like component

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

This is the author accepted manuscript. The final version is available from Nature Publishing Group via http://dx.doi.org/10.1038/ng.3448Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the elderly, with limited therapeutic options. Here we report on a study of >12 million variants, including 163,714 directly genotyped, mostly rare, protein-altering variants. Analyzing 16,144 patients and 17,832 controls, we identify 52 independently associated common and rare variants (P < 5 × 10(-8)) distributed across 34 loci. Although wet and dry AMD subtypes exhibit predominantly shared genetics, we identify the first genetic association signal specific to wet AMD, near MMP9 (difference P value = 4.1 × 10(-10)). Very rare coding variants (frequency <0.1%) in CFH, CFI and TIMP3 suggest causal roles for these genes, as does a splice variant in SLC16A8. Our results support the hypothesis that rare coding variants can pinpoint causal genes within known genetic loci and illustrate that applying the approach systematically to detect new loci requires extremely large sample sizes.We thank all participants of all the studies included for enabling this research by their participation in these studies. Computer resources for this project have been provided by the high-performance computing centers of the University of Michigan and the University of Regensburg. Group-specific acknowledgments can be found in the Supplementary Note. The Center for Inherited Diseases Research (CIDR) Program contract number is HHSN268201200008I. This and the main consortium work were predominantly funded by 1X01HG006934-01 to G.R.A. and R01 EY022310 to J.L.H

Letter to Henry B. Stenzel from Daniel F. Merriam on 1962-11-26

Jackson School of Geoscience