ESPAÇAMENTO NA PRODUÇÃO DE ARROZ DE TERRAS ALTAS IRRIGADO NO CERRADO

A produtividade do arroz de terras altas aumenta com o número de plantas por unidade de área até o ponto em que a competição intraespecífica por nutrientes, água, luz e outros fatores de produção limita o processo produtivo. O objetivo deste trabalho foi avaliar o efeito do espaçamento na produção da cultura do arroz de terras altas irrigado no cerrado. O experimento foi conduzido de maio a outubro do ano de 2015 em Goianésia - GO, na área experimental da Faculdade Evangélica de Goianésia. Foi testada a variedade BRS Primavera em quatro espaçamentos (20, 30, 40 e 50 cm) entre linhas e densidade de 100 sementes por metro e utilizada irrigação por aspersão. O delineamento experimental utilizado foi em blocos casualizados, sendo quatro tratamentos com 3 repetições. Os resultados mostraram que o espaçamento de 30 cm entre linhas proporcionou maior produtividade na variedade BRS Primavera

Influence of pyroligneous extract on water quality and productive performance of Penaeus vannamei/ Influência do extrato pirolenhoso na qualidade de água e no desempenho produtivo de Penaeus vannamei

Water is the main input used in shrimp farming, and the good quality of this natural resource is not only essential for the farmed animals’ welfare, but also for a good profitability at the end of the farming process inaquaculture species. Pyroligneous extract (PE) is a yellow to reddish-brown liquid obtained from the condensation of gases produced by partial wood combustion. This compound has been used for several purposes in different areas, such as in the fertilization of various vegetable crops and in soil conditioning. The objective of the present study was to evaluate the possible benefits of the application of pyroligneous extract on water quality and its consequences on the production performance of Penaeus vannamei. Six 1.0 ha ponds were used, 3 of which were used for the application of pyroligneous extract (WPE) and the other 3 without the extract (wPE) for comparison purposes. The extract was diluted in water and applied directly to the dry soil and after a few hours of reaction the ponds were filled with water and prepared for cultivation. There was a significant difference (p0.05) between the ponds (WPE) and (wPE) in the following water quality parameters: dissolved oxygen, pH, total alkalinity, total hardness, magnesium and silica. However, the values found were within the recommended range for shrimp farming. No significant differences (p0.05) were found in the parameters analyzed in relation to production performance.Water is the main input used in shrimp farming, and the good quality of this natural resource is not only essential for the farmed animals’ welfare, but also for a good profitability at the end of the farming process inaquaculture species. Pyroligneous extract (PE) is a yellow to reddish-brown liquid obtained from the condensation of gases produced by partial wood combustion. This compound has been used for several purposes in different areas, such as in the fertilization of various vegetable crops and in soil conditioning. The objective of the present study was to evaluate the possible benefits of the application of pyroligneous extract on water quality and its consequences on the production performance of Penaeus vannamei. Six 1.0 ha ponds were used, 3 of which were used for the application of pyroligneous extract (WPE) and the other 3 without the extract (wPE) for comparison purposes. The extract was diluted in water and applied directly to the dry soil and after a few hours of reaction the ponds were filled with water and prepared for cultivation. There was a significant difference (p0.05) between the ponds (WPE) and (wPE) in the following water quality parameters: dissolved oxygen, pH, total alkalinity, total hardness, magnesium and silica. However, the values found were within the recommended range for shrimp farming. No significant differences (p0.05) were found in the parameters analyzed in relation to production performance

Aspectos clínicos e radiológicos indicadores de malignidade nos paragangliomas / Clinical and radiological aspects of malignity indicators in paragangliomas

INTRODUÇÃO: Paragangliomas são tumores neuroendócrinos de localização extra-adrenal, originados nos gânglios do sistema nervoso periférico autônomo, distribuídos desde a base do crânio até o assoalho pélvico. São classificados de acordo com sua função em simpáticos e parassimpáticos. A apresentação clínica é variável de acordo com a sua localização e neurotransmissor secretado. Possuem baixa incidência de malignidade, cerca de 25%. METODOLOGIA: Trata-se de uma revisão narrativa na literatura com busca nas bases de dados U.S National Library of Medicine (PubMed) e Scientific Eletronic Library Online (SciELO) utilizando os descritores do DECS: “Paraganglioma”, “Neuroendocrine tumors”,” diagnostic imaging” e “Paraganglioma, Extra-Adrenal”. RESULTADOS E DISCUSSÃO: A diferenciação entre tumores malignos e benignos ainda é incerta, pois determinadas características podem ser observadas em ambos. Este estudo revisional apresenta parâmetros radiológicos em associação com a medicina nuclear e aspectos clínicos, na tentativa de esclarecer esta diferenciação, tanto no diagnóstico como no estadiamento e tratamento. CONCLUSÃO: Até hoje, vários marcadores bioquímicos, histológicos, imunohistoquímicos e radiológicos não demonstraram individualmente a capacidade de determinar malignidade. No entanto, algumas características desses exames quando correlacionados parecem ter relação com o risco potencial maligno.

Os principais tipos e manifestações da Cirrose Hepática: uma atualização clínica

Introdução: A cirrose hepática é um processo patológica crônico, considerado a hepatopatia mais comum, definido como a conversão difusa morfoestrutural por nódulos de arquitetura anômalo envoltos por fibrose. Objetivou-se descrever os tipos mais relevantes de cirrose e suas devidas manifestações. Metodologia: Trata-se de uma revisão bibliográfica, fundamentada nas plataformas do SciELO, PubMed, Scopus, utilizando os termos “hepatical cirrhosis”, “liver disease” e “hepatocellular insufficiency” a qual através da revisão narrativa, abordou amplamente a respeito da contextualização da cirrose e as principais etiologias. Resultados e Discussão: Foi analisado que tal condição afeta qualquer faixa etária, sexo, etnia e independe da classe socioeconômica, mas as diversas etiologias impõem um perfil epidemiológico específico conforme a aparição. As principais origens abordam o tipo alcoólico, hepatite, aplicação crônica de alguns fármacos e esteatose gordurosa ou não. Ademais, estima-se que estas afetam a anatomofuncionalidade do órgão responsável por grande parte da homeostase, culminando em diversas manifestações clínicas.  Conclusão: A cirrose é uma consequência grave de fatores de base em estágio avançado, a qual devido ao seu curso geralmente silencioso culmina no desenvolvimento e progressão clínica. Neste contexto, a atenção aos fatores predisponentes como alimentação rica em lipídios, estilismo, negligência a exames de rotina, sedentarismo e obesidade contribuem constituem medidas eficazes de prevenção primária.&nbsp

Physical exercise and regulation of intracellular calcium in cardiomyocytes of hypertensive rats

Link errado. Favor verificar.Regulation of intracellular calcium (Ca2+) in cardiomyocytes is altered by hypertension; and aerobic exercise brings benefits to hypertensive individuals. To verify the effects of aerobic exercise training on contractility and intracellular calcium (Ca2+) transients of cardiomyocytes and on the expression of microRNA 214 (miR-214) in the left ventricle of spontaneously hypertensive rats (SHR). SHR and normotensive Wistar rats of 16 weeks were divided into 4 groups -sedentary hypertensive (SH); trained hypertensive (TH); sedentary normotensive (SN); and trained normotensive (TN). Animals of the TH and TN groups were subjected to treadmill running program, 5 days/week, 1 hour/day at 60-70% of maximum running velocity for 8 weeks. We adopted a p ≤ 0.05 as significance level for all comparisons. Exercise training reduced systolic arterial pressure in hypertensive rats. In normotensive rats, exercise training reduced the time to 50% cell relaxation and the time to peak contraction and increased the time to 50% decay of the intracellular Ca2+ transients. In SHR, exercise increased the amplitude and reduced the time to 50% decay of Ca2+transients. Exercise training increased the expression of miR-214 in hypertensive rats only. The aerobic training applied in this study increased the availability of intracellular Ca2+ and accelerated the sequestration of these ions in left ventricular myocytes of hypertensive rats, despite increased expression of miR-214 and maintenance of cell contractility

Antinociceptive action of Vanillosmopsis arborea in male mice

Objective: Vanillosmopsis arborea Baker (Asteraceae) has high economic value from Chapada to Araripe and its bark essential oil is a potential source of alpha-bisabolol. The present study aimed to elucidate the antinociceptive and antipruritic properties of the essential oil of V. arborea Baker (EOVA) in mice. Materials and Methods: The antinociceptive activity was assessed using the capsaicin, glutamate, hot plate and cold allodynia tests. The antipuritic effects were also verified based on histamine-induced scratching behavior. Results: EOVA reduced the paw licking induced by capsaicin, but not that induced by glutamate. The essential oil increased the latency time in the hot plate, attenuated the cold allodynia induced by acetone and inhibited histamine-induced scratching behavior. Conclusion: The experimental data demonstrated that EOVA showed central and peripheral antinociceptive activity and antipruritic effect

Topical Antinociceptive Effect of Vanillosmopsis arborea

This study aimed to assess the possible topical antinociceptive activity of Vanillosmopsis arborea Baker essential oil (EOVA) and to clarify the underlying mechanism, using the acute model of chemical (eye wiping) nociception in mice. EOVA (25 to 200 mg/kg; p.o. and topical) evidenced significant antinociception against chemogenic pain in the test model of formalin-induced neuroinflammatory pain. Local application of 5 M NaCl solution on the corneal surface of the eye produced a significant nociceptive behavior, characterized by eye wiping. The number of eye wipes was counted during the first 30 s. EOVA (25, 50, 100, and 200 mg/kg; p.o. and topical) significantly decreased the number of eye wipes. Naloxone, yohimbine, L-NAME, theophylline, glibenclamide, and ruthenium red had no effect on the antinociceptive effect of EOVA. However, ondansetron, p-chlorophenylalanine methyl ester (PCPA), capsazepine, prazosin, and atropine prevented the antinociception induced by EOVA. These results indicate the topical antinociceptive effect of EOVA and showed that 5-HT, α1, TRPV1, and central muscarinic receptors might be involved in the antinociceptive effect of EOVA in the acute corneal model of pain in mice

Physical Exercise and Regulation of Intracellular Calcium in Cardiomyocytes of Hypertensive Rats

Abstract Background: Regulation of intracellular calcium (Ca2+) in cardiomyocytes is altered by hypertension; and aerobic exercise brings benefits to hypertensive individuals. Objective: To verify the effects of aerobic exercise training on contractility and intracellular calcium (Ca2+) transients of cardiomyocytes and on the expression of microRNA 214 (miR-214) in the left ventricle of spontaneously hypertensive rats (SHR). Methods: SHR and normotensive Wistar rats of 16 weeks were divided into 4 groups -sedentary hypertensive (SH); trained hypertensive (TH); sedentary normotensive (SN); and trained normotensive (TN). Animals of the TH and TN groups were subjected to treadmill running program, 5 days/week, 1 hour/day at 60-70% of maximum running velocity for 8 weeks. We adopted a p ≤ 0.05 as significance level for all comparisons. Results: Exercise training reduced systolic arterial pressure in hypertensive rats. In normotensive rats, exercise training reduced the time to 50% cell relaxation and the time to peak contraction and increased the time to 50% decay of the intracellular Ca2+ transients. In SHR, exercise increased the amplitude and reduced the time to 50% decay of Ca2+ transients. Exercise training increased the expression of miR-214 in hypertensive rats only. Conclusion: The aerobic training applied in this study increased the availability of intracellular Ca2+ and accelerated the sequestration of these ions in left ventricular myocytes of hypertensive rats, despite increased expression of miR-214 and maintenance of cell contractility

Mesenchymal stem cell therapy associated with endurance exercise training: Effects on the structural and functional remodeling of infarcted rat hearts

We tested the effects of early mesenchymal stem cell (MSC) therapy associated with endurance exercise on the structural and functional cardiac remodeling of rats with myocardial infarctation (MI). Male Wistar rats (40 days old) were divided into 6 groups: control and exercise sham; control and exercise MI; and control and exercise MI MSC. MI was surgically induced and bone marrow-derived MSCs were immediately injected via caudal vein (concentration: 1 × 106 cells). Twenty-four hours later ET groups exercised on a treadmill (5 days/week; 60 min/day; 60% of maximal running velocity) for 12 weeks. Structural and functional changes were determined by echocardiography. Contractility and intracellular global calcium ([Ca2 +]i) transient were measured in myocytes from the left ventricular (LV) non-infarcted area. Calcium regulatory proteins were measured by Western blot. MI increased (p < 0.05) heart, ventricular and LV weights and its ratios to body weight; LV internal dimension in diastole (LVID-D) and in systole (LVID-S) and LV free wall in diastole (LVFW-D), but reduced the thickness of interventricular septum in systole (IVS-S), ejection fraction (EF) and fractional shortening (FS). MI augmented (p < 0.05) the times to peak and to half relaxation of cell shortening as well as the amplitude of the [Ca2 +]i transient and the times to peak and to half decay. Early MSCs therapy restored LVFW-D, IVS-S and the amplitude and time to half decay of the [Ca2 +]i transient. Early endurance exercise intervention increased (p < 0.05) LVFW-S, IVS-S, EF and FS, and reduced the times to peak and to half relaxation of cell shortening, and the amplitude of the [Ca2 +]i transient. Exercise training also increased the expression of left ventricular SERCA2a and PLBser16. Nevertheless, the combination of these therapies did not cause additive effects. In conclusion, combining early MSCs therapy and endurance exercise does not potentiate the benefits of such treatments to structural and functional cardiac remodeling in infarcted rat