Anterior Subluxation after Total Hip Replacement Confirmed by Radiographs: Report of Two Cases

Demonstrable anterior subluxation of the femoral head after a total hip arthroplasty is a rare complication and is usually transient. Both a case of recurrent subluxation and a case of chronic subluxation are described in this paper, each one presenting with unexpected femoral head eccentricity in the acetabulum on radiograph. We show how this unusual complication can be successfully identified and treated

Anterior-Based Muscle Sparing Approach for Total Hip Arthroplasty

A high value, high quality and low cost surgery: a 7.5 year single-center, retrospective case serieshttps://knowledgeconnection.mainehealth.org/lambrew-retreat-2021/1009/thumbnail.jp

Conversion Total Hip Arthroplasty: Perioperative and Postoperative Outcomes with the ABLE Approach

The ABLE™ Approach for Conversion Total Hip Arthroplasty decreases surgical duration and length of stayhttps://knowledgeconnection.mainehealth.org/lambrew-retreat-2023/1022/thumbnail.jp

Shortening the Postoperative Length of Stay following Total Knee Arthroplasty does not Negatively Impact Short-term Patient Outcomes; a Retrospective Review of the Response to the COVID-19 Pandemic

Safely Decreasing Postoperative Length of Stay for Total Knee Arthroplasty (TKA) Patients Following the COVID-19 Pandemichttps://knowledgeconnection.mainehealth.org/lambrew-retreat-2023/1024/thumbnail.jp

The Use of the iPACK Block with the Adductor Canal Block (ACB) Decreases 48-hour Narcotic Usage and Postoperative Pain following Total Knee Arthroplasty

Adductor Canal and iPACK Blocks reduce pain levels and narcotic consumption following Total Knee Arthroplastyhttps://knowledgeconnection.mainehealth.org/lambrew-retreat-2023/1023/thumbnail.jp

Patterns within Patterns within the Smart Living Experience

Modern technology is increasingly being employed to create a “smart” living experience. These “smart” technology entities are producing copious of amounts data, which in turn rely on increased storage, distribution and computation capacity to manage the data. Depending on the scenario, the diversity of piecemeal solutions almost reflects the diversity of problems they address. But some solutions can be reapplied. In the field of computing, design patterns can provide a general, reusable solution to commonly recurring problems within a given context through software design. This work seeks to determine the core elements of a technology-independent design pattern format and an open software framework can be developed to capture, share and redeploy existing successful and reusable strategies for commonly encountered smart environment use cases. Applying in areas such as assistive technology, energy management and environmental monitoring. The underpinning notion of this paper is to introduce “how, where and why” a rule set based in “design pattern” format could contribute to describe a general “understanding” of given cases in the smart environment domain, as well as allow different processes to collaborate with each other

Adenovirus vector delivery stimulates natural killer cell recognition

We report that delivery of first-generation replication-deficient adenovirus (RDAd) vectors into primary human fibroblasts is associated with the induction of natural killer (NK) cell-mediated cytolysis in vitro. RDAd vector delivery induced cytolysis by a range of NK cell populations including the NK cell clone NKL, primary polyclonal NK lines and a proportion of NK clones (36 %) in autologous HLA-matched assays. Adenovirus-induced cytolysis was inhibited by antibody blocking of the NK-activating receptor NKG2D, implicating this receptor in this function. NKG2D is ubiquitously expressed on NK cells and CD8+ T cells. Significantly, γ-irradiation of the vector eliminated the effect, suggesting that breakthrough expression from the vector induces at least some of the pro-inflammatory responses of unknown aetiology following the application of RDAd vectors during in vivo gene delivery

Adenovirus-mediated Expression of Aquaporin-5 in Epithelial Cells

A recombinant adenovirus coding for rat aquaporin-5 was constructed and plaque purified. The recombinant adenovirus (AdrAQP5) mediated the expression of aquaporin-5 in rat and human salivary cell lines and in dog kidney cells in vitro as demonstrated by Northern blot and Western blot analyses, and by confocal microscopy after immunofluorescent labeling. In kidney cells, expression of the transgene was optimal if cells were infected at their basolateral surface, a phenomenon associated with the distribution of integrin receptors on these cells. The expressed aquaporin-5 protein was functionally active because viral-mediated gene transfer resulted in a significant increase in the osmotically directed net fluid secretion rate across monolayers of kidney cells. AdrAQP5 should provide an efficient and useful means to impart facilitated water permeability to cells lacking such a pathway