The Influence of Short-term Quercetin Supplementation on Peak Oxygen Uptake during Simulated Altitude Exposure in Trained Cyclists

Endurance performance and peak oxygen uptake (VO2peak) decline as altitude increases. Some data exist suggesting that quercetin supplementation improves aerobic capacity in trained and untrained individuals at sea-level (normobaric normoxic conditions). Few studies have examined the effects of quercetin on endurance performance during simulated altitude exposure (normobaric hypoxic conditions). The purpose of this study was to determine the effects of consuming 1000 mg·day-1 of quercetin for two weeks on cycling VO2peak in healthy trained male cyclists performing under normobaric normoxic and hypoxic conditions (NP and HP, respectively). Fourteen age-matched healthy male subjects were randomized to either a placebo or quercetin group. Baseline and post supplementation VO2peak values were quantified during incremental cycling under normobaric normoxic (FIO2 = 20.9%) and normobaric hypoxic (FIO2 = 13.6 + 0.2%) conditions. Subjects consumed capsules twice daily with either 500 mg quercetin or placebo (Tang) for two weeks and were re-assessed. Test order was randomized and assessments were separated by 48-72 hours. At baseline, there were no significant differences between groups for VO2peak normobaric normoxic trials (NPbaseline Placebo vs. NPbaseline Quercetin = 58.7+8.8 and 61.5+7.9 ml . kg-1 . min-1, respectively, p = 0.541) and normobaric hypoxic trials (HPbaseline Placebo vs. HPbaseline Quercetin = 48.5+8.3 and 50.8+4.8 ml . kg-1 . min-1, respectively, p = 0.534). No significant differences were found after treatment (Placebo: NPbaseline vs. NPpost = 58.7+ 8.8 and 56.7+7.4 ml . kg-1 . min-1, respectively, p = 0.10; HPbaseline vs .HPpost = 48.5+8.3 and 47.1+8.3, respectively, p = 0.50; Quercetin: NPbaseline vs. NPpost = 61.5+7.9 and 62.4+7.3 ml . kg-1 . min-1, respectively, p = 0.558; HPbaseline vs. HPpost = 50.8+4.8 and 51.2+3.8 ml . kg-1 . min-1, respectively, p= 0.656. These data suggest that short-term quercetin supplementation at 1000 mg . day-1 does not affect VO2peak elicited via incremental maximal cycle testing under normobaric normoxic and hypoxic conditions in trained male cyclists. Furthermore, quercetin supplementation did not attenuate the decline in VO2peak that was evident in the normobaric hypoxic condition

Partnerships with Purpose: The FEA and ASCA Joint Communication and Collaboration Guide

The Fraternity Executives Association and its members seek to form an open and collaborative partnership with host institutions and student conduct staff members to fairly and appropriately adjudicate organizational conduct issues. In support of this effort, the Association for Student Conduct Administration and the Fraternity Executives Association have partnered together to produce a guidance document that is intended to provide suggested protocol for both inter/national and campus conduct staff when working together to address an allegation of chapter misconduct. The presenters will review the components and suggested implementation of this guidance

Psychological interventions to improve psychological well-being in people with dementia or mild cognitive impairment: systematic review and meta-analysis protocol

Open Access ArticleINTRODUCTION: Dementia and mild cognitive impairment are associated with an increased risk of depression, anxiety, psychological distress and poor mental health-related quality of life. However, there is a lack of research examining the evidence base for psychological interventions targeting general psychological well-being within this population. Furthermore, there is little research relating to the design of randomised controlled trials examining psychological interventions for dementia and mild cognitive impairment, such as effective recruitment techniques, trial eligibility and appropriate comparators. METHODS AND ANALYSIS: Systematic review of electronic databases (CINAHL; EMBASE; PsychInfo; MEDLINE; ASSIA and CENTRAL), supplemented by expert contact, reference and citation checking, and grey literature searches. Published and unpublished studies will be eligible for inclusion with no limitations placed on year of publication. Primary outcomes of interest will be standardised measurements of depression, anxiety, psychological distress or mental health-related quality of life. Eligibility and randomisation proportions will be calculated as secondary outcomes. If data permits, meta-analytical techniques will examine: (1) overall effectiveness of psychological interventions for people with dementia or mild cognitive impairment in relation to outcomes of depression, anxiety, psychological distress or mental health-related quality of life; (2) clinical and methodological moderators associated with effectiveness; (3) proportions eligible, recruited and randomised. ETHICS AND DISSEMINATION: Ethical approval is not required for the present systematic review. Results will inform the design of a feasibility study examining a new psychological intervention for people with dementia and depression, with dissemination through publication in peer-reviewed journals and presentations at relevant conferences. TRIAL REGISTRATION NUMBER: CRD42015025177.National Institute for Health Research (NIHR

Smashing New Results on Aspectual Framing: How People Talk About Car Accidents

How do people describe events they have witnessed? What role does linguistic aspect play in this process? To provide answers to these questions, we conducted an experiment on aspectual framing. In our task, people were asked to view videotaped vehicular accidents and to describe what happened (perfective framing) or what was happening (imperfective framing). Our analyses of speech and gesture in retellings show that the form of aspect used in the question differentially influenced the way people conceptualized and described actions. Questions framed with imperfective aspect resulted in more motion verbs (e.g., driving), more reckless language (e.g., speeding), and more iconic gestures (e.g., path gesture away from the body to show travel direction) than did questions framed with perfective aspect. Our research contributes novel insights on aspect and the construal of events, and on the semantic potency of aspect in leading questions. The findings are consistent with core assumptions in cognitive linguistics, including the proposal that linguistic meaning, including grammatical meaning, is dynamic and grounded in perceptual and cognitive experience

Developing an Instrument to Measure Physical Activity Related Self-Worth in Women: Rasch Analysis of the Women\u27s Physical Activity Self-Worth Inventory (WPASWI)

Objectives: The objective of this study is to report on the development of an instrument to assess non-physical aspects of physical activity (PA) -related self-worth (SW). Methods: Three hundred thirty five women (mean age = 36.69 ± 15.94 yrs, BMI = 24.87 ± 4.56) completed the Women’s Physical Activity Self-Worth Inventory (WPASWI), General SW Scale, and a PA Questionnaire. Rasch analysis was used to evaluate the WPASWI. Results: Three PA-related SW subscales were identified: PA Knowledge (16 items), PA Emotional (13 items), and PA Social (8 items). Rasch analysis supported construct validity, and items demonstrated acceptable internal consistency (Cronbach’s alpha = .90, .87 and .72) and test re-test reliability (r = .79, .70, .81). Women who reported regular PA participation had higher PA Knowledge, PA Emotional, PA Social, and General SW than those who reported some or no PA (p \u3c .01) and correlations between Knowledge, Emotional, and Social SW subscales and General SW were .207, .130, and .220, respectively. PA Knowledge and PA Emotional SW had stronger correlations with PA (r = .344, .273, respectively) than did General SW (r = .133). Conclusions: The WPASWI demonstrated good internal consistency, reliability, construct validity and a stronger relationship with PA than a General SW instrument

Reconciling Epidemiology and Social Justice in the Public Health Discourse Around the Sexual Networks of Black Men Who Have Sex With Men

Several studies have implicated the sexual networks of Black men who have sex with men (MSM) as facilitating disproportionally high rates of new HIV infections within this community. Although structural disparities place these networks at heightened risk for infection, HIV prevention science continues to describe networks as the cause for HIV disparities, rather than an effect of structures that pattern infection. We explore the historical relationship between public health and Black MSM, arguing that the current articulation of Black MSM networks is too often incomplete and counterproductive. Public health can offer a counternarrative that reconciles epidemiology with the social justice that informs our discipline, and that is required for an effective response to the epidemic among Black MSM