Search for sterile neutrinos in the CC νμ mode at the new CERN-SBLNF

The possible existence of non-active neutrinos for the ElectroWeak interactions was first proposed in 1967 by B. Pontecorvo who named them “sterile” neutrinos. Recent tensions among world-wide experimental data renewed the possibility of one or more sterile neutrino states. Several “anomalies” emerged in radioactive sources and reactor neutrino experiments, as well as the long-standing LSND and the recent MiniBooNE hints for neutrino and antineutrino oscillations with a Δm2 at the eV 2 scale, not compatible with the standard 3 × 3 neutrino mixing scenario. While a huge effort is being devoted to establish the standard three-neutrino mixing paradigm no conclusive experiment was carried out to unambiguously settle these anomalies sofar. Very recently an experimental search for sterile neutrinos with a new CERN-SPS neutrino beam using muon spectrometers and large LAr detectors has been proposed. The accurate disentangling of νμ from ν¯μ will allow to investigate the interplay of the different possible oscillation scenarios, as well as the interplay between disappearance and appearance of different neutrino states and flavors. The proposed experiment will offer remarkable discovery potentials, collecting a very large number of unbiased events both in the neutrino and antineutrino channels, largely adequate to definitely settle the origin of the ν oscillation related anomalies. We will discuss the CERN project focussing on the measure of the Charge Current νμ mode

The effect of exposure to low frequency electromagnetic fields (EMF) as an integral part of the housing system on anxiety-related behaviour, cognition and welfare in two strains of laboratory mouse.

Electromagnetic field (EMF) technology has the potential to improve scientific data capture and welfare assessment by allowing automated data collection from individual cages. How- ever, it is important to determine any impact that a new technology itself may have on animal welfare, and previous studies have found contrasting results of EMF on laboratory rodent anxiety-like behaviour and cognition. We therefore investigated whether there was an effect of low frequency EMF experienced continuously over a six-week period, as an integral part of the animal housing system, on measures of mouse anxiety-related behaviour, cognition and welfare. We housed mice (N = 80) of two strains (BALB/cAnNCrl and C57BL/6NCrl) separately in Individually Ventilated Cages (IVCs) in groups of four, either with the EMF plate turned ‘on’ or ‘off’ (n = 5). Some measures, e.g. food and water utilisation, were col- lected at regular intervals, whereas measures of anxiety-like behaviour (e.g. open field test) and cognitive performance (novel-object recognition test) were collected only at the end of the study. We found expected strong strain differences in most measures, e.g. latency to leave the starting square in an open field test, with C57BL/6NCrl mice moving away sooner, and interactions between strain and time for those measures recorded at more than one time point, e.g. significant weight gain over time for both strains, but with BALB/cAnNCrl mice weighing more. However, we found no significant effects of treatment (EMF ‘on’/‘off’) for any of the measures collected. These results indicate that, for the measures recorded here, there was no measurable impact on the behaviour and welfare of low frequency EMF exposure experienced continuously over a six-week period. Housing systems that include EMF monitoring technology may therefore be suitable for use without influencing either ani- mal welfare or scientific outcomes

HUBUNGAN ANTARA STATUS SOSIAL EKONOMI DENGAN STATUS GIZI PADA ANAK USIA 24-59 BULAN DI DESA WORI KECAATAN WORI KABUPATEN MINAHASA UTARA

Gizi merupakan salah satu faktor sangat terpenting dalam menentukan kualtas sumber daya manusia. Salah satu indikator yang menentukan pertumbuhan anak yaitu dari kulitas status gizi yang begitu  sangat baik. Adalagi faktor yang dapat mempengaruhi status gizi anak yaitu pendidikan, pekerjaan dan juga pendapatan . Tujuan penelitian ini mencari hubungan antara status sosial ekonomi dgn status gizi pada anak usia 24-59 bulan di Desa Wori Kecamatan Wori Kabupaten Minahasa Utara. Desain penelitian ini yang digunakan yaitu  analitik Cross-Sectional. Populasi adalah seluruh anak dengan usia 24-59 bulan, dengan sampel penelitian ini seluruh jumlh populasi yaitu 95 anak. Penelitian di laksanakan  bulan Mei-Juni 2019. Hasil penelitian  menunjukkan status gizi bedasarkan (BB/U) status gizi kurang 11 (11,6 %) dan status gizi baik  84 (88,4%). Indeks status gizi (BB/TB) status gizi kurus sebanyak 15 (15,8%) dan 80 (84,2%) status gizi normal. Indeks status gizi  (TB/U) 19 (18,9)  pendek dan (IMT/U) status gizi kurus sebanyak 18 (18,9%) dan 77 (81,1%) status gizi normal. Karakteristik status sosial ekonomi seperti pendidikan orang tua mendominasi pada tingkat pendidikan rendah. Sebanyak 87,4% ibu  bekerja di dalam rumah atau menjadi Ibu Rumah Tangga. Pendapatan keluarga sebagian termasuk pendapatan rendah 87 (91,6%). Berdasarkan hasil uji chi quare  ada hubungan antara pendidikan ayah dengan status gizi (IMT/U)  (p= 0.001). Pendidikan ibu (IMT/U)  (p= 0,001). Berdasarkan hasil  Fisher Exact test ini tidak terdapat hubungan antara pekerjaan ibu dengan status gizi (IMT/U) (p= 0.591) & begitu juga tiadak terdapat adanya hubungan pendapatan keluarga dengan status gizi (IMT/U) (p= 0,345). Kesimpulan dari penelitian ini terdapat hubungan antara pendidikan orang tua dengan status gizi anak (IMT/U), pekerjaan ibu serta pendapatan keluarga tidak terdapat hubungan dengan status gizi anak (IMT/U). Disarankan kepada orangtua untuk memperhatikan lebih baik  lagi asupan makanan bagi anak baik dari segi yang  berkualitas maupun kuantitas. Juga bagi orang tua harus rajin pergi ke posyandu mencari informasi dengan mengikuti penyuluhan-penyuluhan tentang masalah gizi pada anak.  Kata Kunci: Sosial Ekonomi Dan Status Gizi  ABSTRACTNutrition is an essential factor in determining the quaity of human resources. One indicator that determines the growth of chiildren is the quality of good nutritional statuss. The factors that can affect the nutritionl status of children are educatioon, employment, and incomee. The purpose oof this study to lok is for a relationship between socioeconomic status nutritional status  children aged 24-59 months in Wori Village, Wori District, North Minahasa Regency. The design of this researchh is analytic design with a Cross-Sectional approach. The population is all children aged 24-59 monthss, the sample of this study is the total population of 95 children. This research was conducted in May-June 2019. Based on nutritional status a (BB/U) there were 11 (11.6%) underweight and 84 (88.4%) good nutritin. Nutritional status index (BB/TB) contained thin nutritional status of 15 (15.8%) and 80 (84.2%) normal nutrition. Nutritional status index (TB/U) and (IMT/U) there are underweight nutritional status of 18 (18.9%) and 77 (81.1%) status normal nutrition. Characteristics of socioeconomic status such as mother and father education predominate at low levels of education. As many as 87.4% of mothers do not work or become a housewife. Family income is mostlly included in the low incme of 87 (91.6%). Based on the results of the chi-square test, the father 's education (IMT/U) is obtained p-value = 0.001. Maternal education (IMT/ U) p-value = 0.001. Based on Fisher Exact test Work motheer test results (IMT/U) p = 0.591 and family incomee (IMT/ U) p = 0.345. This study concludes that the father education and mother' education have a relationship with the nutritional status of children (IMT / U), and maternal work and family income have no relationship with the nutritional status of children (IMT/ U). It is recommended for parents to pay attention to food intake for children both in terms of quality and quantity. Also for parents to be diligent in going to the Integrated Healthcare Center looking for information by following counseling about nutrition problems in children. Keywords: Socio-Economic and Nutritional Statu

Environmental tobacco smoke: health policy and focus on Italian legislation.

Worldwide tobacco smoking kills nearly 6 million people each year, including more than 600,000 non-smokers who die from smoke exposure. Environmental tobacco smoke (ETS, also called secondhand smoke, involuntary smoke, or passive smoke) is the combination of sidestream smoke, the smoke given off by a burning tobacco product and mainstream smoke, the smoke exhaled by smokers. People may be exposed to ETS in homes, cars, workplaces, and public places, such as bars, restaurants, and recreational settings. In addition, there is another type of smoke which until now has not been recognized: the so-called thirdhand smoke, that comes from the reaction of mainstream smoke and environmental nitrous acid (HNO2) making carcinogenic tobacco-specific nitrosamines (TSNAs). The effects of ETS on human health are well-known, passive smoking is harmful to those who breathe the toxins and it is a serious problem for public health. The smoking ban in Italy had reduced ETS pollution, as in the United States and in other countries all over the world. However, the implementation of comprehensive legislation on smoking policy will necessitate other tobacco control measures for its successful fulfillment: increased media awareness, telephone smoking cessation helplines and smoking cessation support services could be an opportunity to ensure awareness, comprehension and support to those who want to quit smoking. The effectiveness of legislative efforts will also depend on successful enforcement of smoking bans and compliance with the legislation. This review summarizes the evidences about the effect of ETS and provides an overview of smoke-free laws and policies

Frontal brain asymmetries as effective parameters to assess the quality of audiovisual stimuli perception in adult and young cochlear implant users

How is music perceived by cochlear implant (CI) users? This question arises as "the next step" given the impressive performance obtained by these patients in language perception. Furthermore, how can music perception be evaluated beyond self-report rating, in order to obtain measurable data? To address this question, estimation of the frontal electroencephalographic (EEG) alpha activity imbalance, acquired through a 19-channel EEG cap, appears to be a suitable instrument to measure the approach/withdrawal (AW index) reaction to external stimuli. Specifically, a greater value of AW indicates an increased propensity to stimulus approach, and vice versa a lower one a tendency to withdraw from the stimulus. Additionally, due to prelingually and postlingually deafened pathology acquisition, children and adults, respectively, would probably differ in music perception. The aim of the present study was to investigate children and adult CI users, in unilateral (UCI) and bilateral (BCI) implantation conditions, during three experimental situations of music exposure (normal, distorted and mute). Additionally, a study of functional connectivity patterns within cerebral networks was performed to investigate functioning patterns in different experimental populations. As a general result, congruency among patterns between BCI patients and control (CTRL) subjects was seen, characterised by lowest values for the distorted condition (vs. normal and mute conditions) in the AW index and in the connectivity analysis. Additionally, the normal and distorted conditions were significantly different in CI and CTRL adults, and in CTRL children, but not in CI children. These results suggest a higher capacity of discrimination and approach motivation towards normal music in CTRL and BCI subjects, but not for UCI patients. Therefore, for perception of music CTRL and BCI participants appear more similar than UCI subjects, as estimated by measurable and not self-reported parameters

Tap For Battle: Perancangan Casual Game pada Smartphone Android

Smartphones have become a necessity. Almost everyone uses a smartphone in a variety of activities. Both young and old are sure to utilize this technology, for a wide range of activities such as doing the work, doing school work or enjoying entertainment. The purpose of this research is to build a casual-action game with war theme. The game is built for Android smartphone that has multi touch screen capability. The research methods used in this research are data collection and analysis method including user analysis with questionnaire. Furthermore, IMSDD method is implemented for game design and development phase including system requirement analysis, system design, system implementation, finally system evaluation. In this research, we conclude that 83.9% participants enjoyed the game with touch-screen as the game control

π-Conjugated Macrocycles Bearing Angle-Strained Alkynes

Angle‐strained alkyne‐containing π‐conjugated macrocycles are attractive compounds both in functional materials chemistry and biochemistry. Their interesting reactivity as well as photophysical and supramolecular properties have been revealed in the past three decades. This review highlights the recent advances in angle‐strained alkyne‐containing π‐conjugated macrocycles, especially their synthetic methods, the bond angles of alkynes (∠sp at C≡C−C), and their functions. The theoretical and experimental research on cyclo[n]carbons and para‐cyclophynes consisting of ethynylenes and para‐phenylenes are mainly summarized. Related macrocycles bearing other linkers, such as ortho‐phenylenes, meta‐phenylenes, heteroaromatics, biphenyls, extended aromatics, are also overviewed. Bond angles of strained alkynes in π‐conjugated macrocycles, which are generable, detectable, and isolable, are summarized at the end of this review

A five-year survey for plastic surgery malpractice claims in Rome, Italy

(1) Introduction: Medical malpractice claims against both health institutions and physicians are a crucial topic in Italy, as well as in other countries, particularly regarding civil proceedings. Our study reports an analysis of all of the malpractice judgments concerning plastic surgery decided in the Civil Court of Rome between 2012 and 2016. (2) Methods: the database of the Observatory Project on Medical Responsibility (ORMe) was analyzed, which collects all of the judgments of the Civil Court of Rome, that is, the first instance district court. Therefore, neither the jurisprudence of the second level court nor that of the Supreme Court was taken into account. (3) Results: 144 judgments concerning plastic surgery were delivered in the five-year period of 2012–2016 (corresponding to 10.6% of total professional liability verdicts of the Civil Court of Rome in the same period). In 101/144 cases (70.14%), the claim was accepted. A total of €4,727,579.00 was paid in compensation for plastic surgery malpractice claims, with a range from a minimum amount of €1555.96 to a maximum amount of €1,425,155.00 and an average compensation of €46,807.71 per claim that was significantly lower compared to other surgical disciplines. (4) Conclusions: Our data confirm that the analyzed branch has a high litigation rate, with a prevalence of convictions for cosmetic procedures over reconstructive ones, both for malpractice and for violation of the informed consent. Plastic surgery is also confirmed among those branches in which the professionals are more frequently sued compared to health institutions

Telemedicine as a Medical Examination Tool During the Covid-19 Emergency: The Experience of the Onco-Haematology Center of Tor Vergata Hospital in Rome

Background: Our study analysed the outpatient activity of the onco-hematology Complex Operative Unit (UOC) of Tor Vergata Hospital, Rome coronavirus disease 2019 (Covid-19) center, where, as a result of the sudden and unexpected emergency, healthcare services were provided through telemedicine procedures that can be considered very close to Telehealth. Aim of the study: our retrospective study aimed to assess the widespread use of telemedicine in terms of feasibility and safety related to adverse events, a crucial experience which will make it possible to predict any effective use of such a method in patients with hematological disorders even after the end of the Covid-19 emergency. Materials and methods: At the Day Hospital clinic, from 8 March to 31 May 2020, an outpatient group received 3828 medical teleconsultations and 11,484 additional contacts following the first examination; each patient examined through the telematic method required an average of three supplementary contacts via e-mail or telephone. Results: The follow-up lasted 145 days, and all the events that occurred were monitored. In total, we recorded 16 clinical adverse events, 5 of which classified as major events, and 11 as minor events. Conclusion: The 3828 telematic clinical examinations and the 11,484 additional contacts following the first examination carried out by the onco-haematology UOC of Tor Vergata Hospital, proved how telemedicine, albeit in its basic form, was a key tool in facing the sanitary emergency caused by the sudden spread of Covid-19. An experience that can be considered reliable enough to be replicated in possible post-Covid-19 emergencies. From a medical forensic point of view, the main issues to consider are informed consent, personal data management and professional responsibility profiles

DTM-based morphometry of the Palinuro seamount (Eastern Tyrrhenian Sea): Geomorphological and volcanological implications

We present a high resolution DTM of the Palinuro Seamount (PS, Tyrrhenian Sea, Italy) resulting from the processing of multibeam swath bathymetry records acquired during the second leg of the “Aeolian 2007” cruise. PS consists of several superimposed volcanoes aligned along a N100°E strike and measures 55×25 km. The western and the central sectors result from the coalescence of collapse structures (calderas) with younger volcanic cones. The eastern sector reveals a more complex and articulated structure. In the central sector, a volcanic crater with a well-preserved rim not obliterated by erosional events suggests a volcanological rejuvenation of this sector. The presence of flat surfaces on the top of the seamount may be due to the formation of marine terraces during the last sea-level lowering. Lateral collapses on the northern and southern flanks of the seamount are probably related to slope instability, as suggested by the presence of steep slopes (25–40°). The main fault affecting PS strikes N65°E and shows a right lateral component of movement. E–W and N10°E striking faults are also present. Assuming that theN100°E deep-seated fault,which is responsible for theemplacement of PS,movedwith sinistral slips, we interpret the N65°E and the N10°E faults as right-lateral (second order) shear and left-lateral (third order) shear, respectively. Due to the particular location of the Palinuro Seamount, the data presented here allow us to better understand the volcanism and the geodynamic processes of the Tyrrhenian Sea