34 research outputs found

    Feministische Geographie

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    Die feministische Geographie verfolgt drei miteinander verbundene Anliegen: Als geographische Geschlechterforschung untersucht sie den Zusammenhang von gesellschaftlicher Räumlichkeit und Geschlechterverhältnissen. Im Rahmen wissenschaftstheoretischer Debatten werden Möglichkeiten der Integration feministischer und geographischer Theoriebildung gesucht. Disziplinpolitisch fokussiert sie bestehende Ungleichheitsverhältnisse und geschlechtsspezifische Arbeitsteilungen in der Hochschulgeographie

    Braucht der Wohnbereich einen Ausgang?: Veränderung des Verhaltens und Wohlbefindens demenzerkrankter Bewohner in Abhängigkeit von der Sichtbarkeit der Ausgangstür

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    Der Umgang mit möglicher Selbstgefährdung demenzerkrankter Bewohner durch das selbständige Verlassen des Wohnbereichs wird in Altenpflegeeinrichtungen häufig und kontrovers diskutiert. In dieser Studie wurde untersucht, ob eine milieutherapeutische Intervention in Form eines Vorhangs vor der Ausgangstür die Bewohner am Verlassen des Wohnbereichs hindert. Das wesentliche Untersuchungsziel war es dabei zu erfassen, ob Veränderungen in Verhalten und Wohlbefinden der Bewohner zu verzeichnen sind

    Geographien der Macht: für einen integrierten Blick auf Raumproduktionen mit Foucault

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    Mit dem spatial turn artikulieren die Geistes- und Sozialwissenschaften das Bedürfnis, sich mit der Räumlichkeit gesellschaftlicher Verhältnisse auseinanderzusetzen. Der vorliegende Beitrag greift dieses Anliegen auf und lotet exemplarisch das Potenzial der Arbeiten Michel Foucaults für eine konsequente Erschließung „materialisierter Geographien“ aus. An drei Beispielen aus seinem Schaffen gehen wir der Frage nach, wie sich Techniken der Wissensproduktion und der Machtausübung mit räumlichen Anordnungs- und Interventionspraktiken verschränken. Unser Plädoyer gilt einem integrierten Blick auf Raumproduktionen, der keine künstliche Trennung von repräsentationalen und materialisierten Geographien vornimmt.The spatial turn in the social sciences and humanities articulates a newfound interest in the spatiality of the social and a desire to further theorize this spatiality. Our article picks up on this debate and explores the potential of the work of Michel Foucault for a conceptualization of „material geographies“. By turning to three examples in Foucault’s work, we highlight the importance of spatial practices for the production of knowledge and the exercise of power. By focusing on these examples, we argue that Foucault offers a unique view on the production of space that rejects an artificial separation between „representational“ and „material geographies“

    Kiel 1969–2019: Die Zukunft der Geographie liegt auch in ihrer Vergangenheit

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    Braucht der Wohnbereich einen Ausgang?: Veränderung des Verhaltens und Wohlbefindens demenzerkrankter Bewohner in Abhängigkeit von der Sichtbarkeit der Ausgangstür

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    Der Umgang mit möglicher Selbstgefährdung demenzerkrankter Bewohner durch das selbständige Verlassen des Wohnbereichs wird in Altenpflegeeinrichtungen häufig und kontrovers diskutiert. In dieser Studie wurde untersucht, ob eine milieutherapeutische Intervention in Form eines Vorhangs vor der Ausgangstür die Bewohner am Verlassen des Wohnbereichs hindert. Das wesentliche Untersuchungsziel war es dabei zu erfassen, ob Veränderungen in Verhalten und Wohlbefinden der Bewohner zu verzeichnen sind

    Urbanität nach exklusivem Rezept. Die Ausdeutung des Städtischen durch hochpreisige Immobilienprojekte in Berlin und Los Angeles

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    Innerstädtisches Wohnen steht zunehmend hoch im Kurs. Wahlweise als „Renaissance der Stadt“, Reurbanisierung oder Gentrifizierung thematisiert, ist das gegenwärtige Interesse von Investor_innen, Projektentwickler_innen und Käufer_innen an innerstädtischen Lagen prägnanter Ausdruck einer fortgesetzten Restrukturierung europäischer und US-amerikanischer Städte. Neben Prozessen der Inwertsetzung und Verdrängung umfasst diese Neuordnung auch die Ebene der Bedeutungen von Stadt und Urbanität. Insbesondere hochpreisige Neubauprojekte konkretisieren derzeit veränderte Vorstellungen bezüglich der Qualität der Stadt, ihrer Nutzer_innen und Nutzungsweisen. Der Beitrag zieht Projekte innerstädtischen Luxuswohnens in Berlin und Los Angeles heran, um dieser baulichen Konkretisierung von Diskursen um Stadt und Urbanität als Aspekt der gegenwärtigen „Renaissance der Stadt“ nachzugehen. In welcher Weise manifestieren sich Vorstellungen des erstrebenswerten städtischen Lebens in aktuellen Projekten hochpreisigen innerstädtischen Wohnungsbaus und welche Implikationen hat dies für die Gestalt der Stadt

    Interaction of Bestrophin-1 and Ca2+ Channel β-Subunits: Identification of New Binding Domains on the Bestrophin-1 C-Terminus

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    Bestrophin-1 modulates currents through voltage-dependent L-type Ca2+ channels by physically interacting with the β-subunits of Ca2+ channels. The main function of β-subunits is to regulate the number of pore-forming CaV-subunits in the cell membrane and modulate Ca2+ channel currents. To understand the influence of full-length bestrophin-1 on β-subunit function, we studied binding and localization of bestrophin-1 and Ca2+ channel subunits, together with modulation of CaV1.3 Ca2+ channels currents. In heterologeous expression, bestrophin-1 showed co-immunoprecipitation with either, β3-, or β4-subunits. We identified a new highly conserved cluster of proline-rich motifs on the bestrophin-1 C-terminus between amino acid position 468 and 486, which enables possible binding to SH3-domains of β-subunits. A bestrophin-1 that lacks these proline-rich motifs (ΔCT-PxxP bestrophin-1) showed reduced efficiency to co-immunoprecipitate with β3 and β4-subunits. In the presence of ΔCT-PxxP bestrophin-1, β4-subunits and CaV1.3 subunits partly lost membrane localization. Currents from CaV1.3 subunits were modified in the presence of β4-subunit and wild-type bestrophin-1: accelerated time-dependent activation and reduced current density. With ΔCTPxxP bestrophin-1, currents showed the same time-dependent activation as with wild-type bestrophin-1, but the current density was further reduced due to decreased number of Ca2+ channels proteins in the cell membrane. In summary, we described new proline-rich motifs on bestrophin-1 C-terminus, which help to maintain the ability of β-subunits to regulate surface expression of pore-forming CaV Ca2+-channel subunits

    Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort

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    State of the climate in 2018

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    In 2018, the dominant greenhouse gases released into Earth’s atmosphere—carbon dioxide, methane, and nitrous oxide—continued their increase. The annual global average carbon dioxide concentration at Earth’s surface was 407.4 ± 0.1 ppm, the highest in the modern instrumental record and in ice core records dating back 800 000 years. Combined, greenhouse gases and several halogenated gases contribute just over 3 W m−2 to radiative forcing and represent a nearly 43% increase since 1990. Carbon dioxide is responsible for about 65% of this radiative forcing. With a weak La Niña in early 2018 transitioning to a weak El Niño by the year’s end, the global surface (land and ocean) temperature was the fourth highest on record, with only 2015 through 2017 being warmer. Several European countries reported record high annual temperatures. There were also more high, and fewer low, temperature extremes than in nearly all of the 68-year extremes record. Madagascar recorded a record daily temperature of 40.5°C in Morondava in March, while South Korea set its record high of 41.0°C in August in Hongcheon. Nawabshah, Pakistan, recorded its highest temperature of 50.2°C, which may be a new daily world record for April. Globally, the annual lower troposphere temperature was third to seventh highest, depending on the dataset analyzed. The lower stratospheric temperature was approximately fifth lowest. The 2018 Arctic land surface temperature was 1.2°C above the 1981–2010 average, tying for third highest in the 118-year record, following 2016 and 2017. June’s Arctic snow cover extent was almost half of what it was 35 years ago. Across Greenland, however, regional summer temperatures were generally below or near average. Additionally, a satellite survey of 47 glaciers in Greenland indicated a net increase in area for the first time since records began in 1999. Increasing permafrost temperatures were reported at most observation sites in the Arctic, with the overall increase of 0.1°–0.2°C between 2017 and 2018 being comparable to the highest rate of warming ever observed in the region. On 17 March, Arctic sea ice extent marked the second smallest annual maximum in the 38-year record, larger than only 2017. The minimum extent in 2018 was reached on 19 September and again on 23 September, tying 2008 and 2010 for the sixth lowest extent on record. The 23 September date tied 1997 as the latest sea ice minimum date on record. First-year ice now dominates the ice cover, comprising 77% of the March 2018 ice pack compared to 55% during the 1980s. Because thinner, younger ice is more vulnerable to melting out in summer, this shift in sea ice age has contributed to the decreasing trend in minimum ice extent. Regionally, Bering Sea ice extent was at record lows for almost the entire 2017/18 ice season. For the Antarctic continent as a whole, 2018 was warmer than average. On the highest points of the Antarctic Plateau, the automatic weather station Relay (74°S) broke or tied six monthly temperature records throughout the year, with August breaking its record by nearly 8°C. However, cool conditions in the western Bellingshausen Sea and Amundsen Sea sector contributed to a low melt season overall for 2017/18. High SSTs contributed to low summer sea ice extent in the Ross and Weddell Seas in 2018, underpinning the second lowest Antarctic summer minimum sea ice extent on record. Despite conducive conditions for its formation, the ozone hole at its maximum extent in September was near the 2000–18 mean, likely due to an ongoing slow decline in stratospheric chlorine monoxide concentration. Across the oceans, globally averaged SST decreased slightly since the record El Niño year of 2016 but was still far above the climatological mean. On average, SST is increasing at a rate of 0.10° ± 0.01°C decade−1 since 1950. The warming appeared largest in the tropical Indian Ocean and smallest in the North Pacific. The deeper ocean continues to warm year after year. For the seventh consecutive year, global annual mean sea level became the highest in the 26-year record, rising to 81 mm above the 1993 average. As anticipated in a warming climate, the hydrological cycle over the ocean is accelerating: dry regions are becoming drier and wet regions rainier. Closer to the equator, 95 named tropical storms were observed during 2018, well above the 1981–2010 average of 82. Eleven tropical cyclones reached Saffir–Simpson scale Category 5 intensity. North Atlantic Major Hurricane Michael’s landfall intensity of 140 kt was the fourth strongest for any continental U.S. hurricane landfall in the 168-year record. Michael caused more than 30 fatalities and 25billion(U.S.dollars)indamages.InthewesternNorthPacific,SuperTyphoonMangkhutledto160fatalitiesand25 billion (U.S. dollars) in damages. In the western North Pacific, Super Typhoon Mangkhut led to 160 fatalities and 6 billion (U.S. dollars) in damages across the Philippines, Hong Kong, Macau, mainland China, Guam, and the Northern Mariana Islands. Tropical Storm Son-Tinh was responsible for 170 fatalities in Vietnam and Laos. Nearly all the islands of Micronesia experienced at least moderate impacts from various tropical cyclones. Across land, many areas around the globe received copious precipitation, notable at different time scales. Rodrigues and Réunion Island near southern Africa each reported their third wettest year on record. In Hawaii, 1262 mm precipitation at Waipā Gardens (Kauai) on 14–15 April set a new U.S. record for 24-h precipitation. In Brazil, the city of Belo Horizonte received nearly 75 mm of rain in just 20 minutes, nearly half its monthly average. Globally, fire activity during 2018 was the lowest since the start of the record in 1997, with a combined burned area of about 500 million hectares. This reinforced the long-term downward trend in fire emissions driven by changes in land use in frequently burning savannas. However, wildfires burned 3.5 million hectares across the United States, well above the 2000–10 average of 2.7 million hectares. Combined, U.S. wildfire damages for the 2017 and 2018 wildfire seasons exceeded $40 billion (U.S. dollars)
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