Nouveaux Orthoptères (Ensifera, Insecta) du Trias des Vosges (France)

Trois nouveaux Orthoptera, Ensifera (Hagloidea et Gryllavoidea) du Grès à Voltzia (Buntsandstein supérieur, Trias inférieur/moyen) des Vosges (France) représentés par des ailes antérieures, sont décrits. Galliagryllavus vogesiacus n. gen., n.sp. (Gryllavidae) montre des affinités avec Gryllavus madyge nicus SHAROV 1968 du Trias de Madygen (Kirghizistan). Triassoparacyrtophyllites bifurcatus n. gen., n.sp. (Tuphellidae) présente des analogies avec Pa racyrtophillites undulatus SHAROV 1968 du Jurassique supérieur de Karatau (Kazakhstan). Voltziahagla pseudoveinosa n. gen., n.sp. (Haglidae) semble proche du genre Archaboilus MARTYNOV 1937 du Jurassique inférieur de Shurab (Tadjikistan). Ces trois Ensifera qui appartiennent à des familles distinctes mettent en évidence la diversité de ce groupe à la limite du Trias inférieur/moyen. Une révision cladistique des Hagloidea et des Gryllavoidea serait nécessaire pour pouvoir déterminer les relations phylogénétiques entre ces différentes familles.Three new Orthoptera, Ensifera (Hagloidea and Gryllavoidea) from the Grés à Voltzia (Upper Buntsandstein, transition Lower / Middle Triassic) of the Vosges (France) are described based on forewings. Galliagryllavus vogesiacus n.gen., n.sp. (Gryllavidae) shows affinities with Gryllavus madygenicus SHAROV 1968 from the Triassic of Madygen (Kirghizistan). Triassoparacyrtophyllites bifurcatus n.gen., n.sp. (Tuphellidae) displays some similarities with Paracyrtophillites undulatus SHAROV 1968 from the Upper Jurassic of Karatau (Kazakhstan). Voltziahagla pseudoveinosa n.gen., n.sp. (Haglidae) seems close to the genus Archaboilus MARTYNOV 1937 from the Lower Jurassic of Shurab (Tadjikistan). These three Ensifera which belong to distinct families underscore the diversity of the Hagloidea and the Gryllavoidea at the boundary between the Lower and Middle Triassic. A cladistic study would be necessary to determine the phylogenetical relationships between the different families

3D Palatography

International audienceStatic palatography has been widely used to investigate consonant articulation. The method is based on the observation of the tongue print (a black paste is spread on the tongue before the production) either directly onto the palate (direct palatography) or onto a pseudo palate (indirect palatography). This study has two main objectives. The first one is to provide an automatic analysis of the tongue print characteristic (size, shape, position onto the palate,...) in order to allow an objective description of the linguopalatal contact.The second one concerns the shape of the palate. Indeed, a simple picture (2D) analysis does not take into account the shape (3D) of the palate vault. To alleviate this 2D limitation, we propose a method based on the use of structured light which enables the computation of the palate shape

A reconfigurable, tendon-based haptic interface for research into human-environment interactions

Human reaction to external stimuli can be investigated in a comprehensive way by using a versatile virtual-reality setup involving multiple display technologies. It is apparent that versatility remains a main challenge when human reactions are examined through the use of haptic interfaces as the interfaces must be able to cope with the entire range of diverse movements and forces/torques a human subject produces. To address the versatility challenge, we have developed a large-scale reconfigurable tendon-based haptic interface which can be adapted to a large variety of task dynamics and is integrated into a Cave Automatic Virtual Environment (CAVE). To prove the versatility of the haptic interface, two tasks, incorporating once the force and once the velocity extrema of a human subject's extremities, were implemented: a simulator with 3-DOF highly dynamic force feedback and a 3-DOF setup optimized to perform dynamic movements. In addition, a 6-DOF platform capable of lifting a human subject off the ground was realized. For these three applications, a position controller was implemented, adapted to each task, and tested. In the controller tests with highly different, task-specific trajectories, the three robot configurations fulfilled the demands on the application-specific accuracy which illustrates and confirms the versatility of the developed haptic interfac

Compressed magnetized shells of atomic gas and the formation of the Corona Australis molecular cloud

We present the identification of the previously unnoticed physical association between the Corona Australis molecular cloud (CrA), traced by interstellar dust emission, and two shell-like structures observed with line emission of atomic hydrogen (HI) at 21 cm. Although the existence of the two shells had already been reported in the literature, the physical link between the HI emission and CrA had never been highlighted until now. We used both Planck and Herschel data to trace dust emission and the Galactic All Sky HI Survey (GASS) to trace HI. The physical association between CrA and the shells is assessed based both on spectroscopic observations of molecular and atomic gas and on dust extinction data with Gaia. The shells are located at a distance between ~140 and ~190 pc, which is comparable to the distance of CrA, which we derived as (150.5 ± 6.3) pc. We also employed dust polarization observations from Planck to trace the magnetic- field structure of the shells. Both of them show patterns of magnetic-field lines following the edge of the shells consistently with the magnetic-field morphology of CrA. We estimated the magnetic-field strength at the intersection of the two shells via the Davis-Chandrasekhar-Fermi (DCF) method. Despite the many caveats that are behind the DCF method, we find a magnetic-field strength of (27 ± 8) μG, which is at least a factor of two larger than the magnetic-field strength computed off of the HI shells. This value is also significantly larger compared to the typical values of a few μG found in the diffuse HI gas from Zeeman splitting. We interpret this as the result of magnetic-field compression caused by the shell expansion. This study supports a scenario of molecular-cloud formation triggered by supersonic compression of cold magnetized HI gas from expanding interstellar bubbles

Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups

Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new genetic loci for obesity. Here we aimed to discover additional obesity loci in extremely obese children and adolescents. We also investigated if these results generalize by estimating the effects of these obesity loci in adults and in population-based samples including both children and adults. We jointly analysed two GWAS of 2,258 individuals and followed-up the best, according to lowest p-values, 44 single nucleotide polymorphisms (SNP) from 21 genomic regions in 3,141 individuals. After this DISCOVERY step, we explored if the findings derived from the extremely obese children and adolescents (10 SNPs from 5 genomic regions) generalized to (i) the population level and (ii) to adults by genotyping another 31,182 individuals (GENERALIZATION step). Apart from previously identified FTO, MC4R, and TMEM18, we detected two new loci for obesity: one in SDCCAG8 (serologically defined colon cancer antigen 8 gene; p = 1.85610 x 10(-8) in the DISCOVERY step) and one between TNKS (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase gene) and MSRA (methionine sulfoxide reductase A gene; p = 4.84 x 10(-7)), the latter finding being limited to children and adolescents as demonstrated in the GENERALIZATION step. The odds ratios for early-onset obesity were estimated at similar to 1.10 per risk allele for both loci. Interestingly, the TNKS/MSRA locus has recently been found to be associated with adult waist circumference. In summary, we have completed a meta-analysis of two GWAS which both focus on extremely obese children and adolescents and replicated our findings in a large followed-up data set. We observed that genetic variants in or near FTO, MC4R, TMEM18, SDCCAG8, and TNKS/MSRA were robustly associated with early-onset obesity. We conclude that the currently known major common variants related to obesity overlap to a substantial degree between children and adults

QUARITE (quality of care, risk management and technology in obstetrics): a cluster-randomized trial of a multifaceted intervention to improve emergency obstetric care in Senegal and Mali

<p>Abstract</p> <p>Background</p> <p>Maternal and perinatal mortality are major problems for which progress in sub-Saharan Africa has been inadequate, even though childbirth services are available, even in the poorest countries. Reducing them is the aim of two of the main Millennium Development Goals. Many initiatives have been undertaken to remedy this situation, such as the Advances in Labour and Risk Management (ALARM) International Program, whose purpose is to improve the quality of obstetric services in low-income countries. However, few interventions have been evaluated, in this context, using rigorous methods for analyzing effectiveness in terms of health outcomes. The objective of this trial is to evaluate the effectiveness of the ALARM International Program (AIP) in reducing maternal mortality in referral hospitals in Senegal and Mali. Secondary goals include evaluation of the relationships between effectiveness and resource availability, service organization, medical practices, and satisfaction among health personnel.</p> <p>Methods/Design</p> <p>This is an international, multi-centre, controlled cluster-randomized trial of a complex intervention. The intervention is based on the concept of evidence-based practice and on a combination of two approaches aimed at improving the performance of health personnel: 1) Educational outreach visits; and 2) the implementation of facility-based maternal death reviews.</p> <p>The unit of intervention is the public health facility equipped with a functional operating room. On the basis of consent provided by hospital authorities, 46 centres out of 49 eligible were selected in Mali and Senegal. Using randomization stratified by country and by level of care, 23 centres will be allocated to the intervention group and 23 to the control group. The intervention will last two years. It will be preceded by a pre-intervention one-year period for baseline data collection. A continuous clinical data collection system has been set up in all participating centres. This, along with the inventory of resources and the satisfaction surveys administered to the health personnel, will allow us to measure results before, during, and after the intervention. The overall rate of maternal mortality measured in hospitals during the post-intervention period (Year 4) is the primary outcome. The evaluation will also include cost-effectiveness.</p> <p>Trial Registration</p> <p>The QUARITE trial is registered on the Current Controlled Trials website under the number ISRCTN46950658 <url>http://www.controlled-trials.com/</url>.</p