10,124 research outputs found
Conical defects in growing sheets
A growing or shrinking disc will adopt a conical shape, its intrinsic
geometry characterized by a surplus angle at the apex. If growth is slow,
the cone will find its equilibrium. Whereas this is trivial if , the
disc can fold into one of a discrete infinite number of states if is
positive. We construct these states in the regime where bending dominates,
determine their energies and how stress is distributed in them. For each state
a critical value of is identified beyond which the cone touches itself.
Before this occurs, all states are stable; the ground state has two-fold
symmetry.Comment: 4 pages, 4 figures, LaTeX, RevTeX style. New version corresponds to
the one published in PR
Interface-mediated interactions: Entropic forces of curved membranes
Particles embedded in a fluctuating interface experience forces and torques
mediated by the deformations and by the thermal fluctuations of the medium.
Considering a system of two cylinders bound to a fluid membrane we show that
the entropic contribution enhances the curvature-mediated repulsion between the
two cylinders. This is contrary to the usual attractive Casimir force in the
absence of curvature-mediated interactions. For a large distance between the
cylinders, we retrieve the renormalization of the surface tension of a flat
membrane due to thermal fluctuations.Comment: 11 pages, 5 figures; final version, as appeared in Phys. Rev.
Space Group Choice for an Octahedral Zn Complex with Nalidixic Acid and (R,R)-Diaminocyclohexane as Ligands: Get the Stereochemistry Right
With this report, the space group of [()()2] is corrected ( : nalidixic acid mono-anion; : diaminocyclohexane) from its wrong description in the literature. In the correct, non-centrosymmetric space group 1 , the crystal structure is well ordered and the stereochemistry is correct. Crystallographic tools to recognize the correct symmetry are described. This work encourages experienced and inexperienced scientists to remain critical about the output of automatic, black-box crystallographic software
Main phase transition in lipid bilayers: phase coexistence and line tension in a soft, solvent-free, coarse-grained model
We devise a soft, solvent-free, coarse-grained model for lipid bilayer
membranes. The non-bonded interactions take the form of a weighted-density
functional which allows us to describe the thermodynamics of self-assembly and
packing effects of the coarse-grained beads in terms of a density expansion of
the equation of state and the weighting functions that regularize the
microscopic bead densities, respectively. Identifying the length and energy
scales via the bilayer thickness and the thermal energy scale, kT, the model
qualitatively reproduces key characteristics (e.g., bending rigidity, area per
lipid molecules, and compressibility) of lipid membranes. We employ this model
to study the main phase transition between the liquid and the gel phase of the
bilayer membrane. We accurately locate the phase coexistence using free energy
calculations and also obtain estimates for the bare and the thermodynamic line
tension.Comment: 21 pages, 12 figures. Submitted to J. Chem. Phy
Contact lines for fluid surface adhesion
When a fluid surface adheres to a substrate, the location of the contact line
adjusts in order to minimize the overall energy. This adhesion balance implies
boundary conditions which depend on the characteristic surface deformation
energies. We develop a general geometrical framework within which these
conditions can be systematically derived. We treat both adhesion to a rigid
substrate as well as adhesion between two fluid surfaces, and illustrate our
general results for several important Hamiltonians involving both curvature and
curvature gradients. Some of these have previously been studied using very
different techniques, others are to our knowledge new. What becomes clear in
our approach is that, except for capillary phenomena, these boundary conditions
are not the manifestation of a local force balance, even if the concept of
surface stress is properly generalized. Hamiltonians containing higher order
surface derivatives are not just sensitive to boundary translations but also
notice changes in slope or even curvature. Both the necessity and the
functional form of the corresponding additional contributions follow readily
from our treatment.Comment: 8 pages, 2 figures, LaTeX, RevTeX styl
Atomic micromotion and geometric forces in a triaxial magnetic trap
Non-adiabatic motion of Bose-Einstein condensates of rubidium atoms arising
from the dynamical nature of a time-orbiting-potential (TOP) trap was observed
experimentally. The orbital micromotion of the condensate in velocity space at
the frequency of the rotating bias field of the TOP was detected by a
time-of-flight method. A dependence of the equilibrium position of the atoms on
the sense of rotation of the bias field was observed. We have compared our
experimental findings with numerical simulations. The nonadiabatic following of
the atomic spin in the trap rotating magnetic field produces geometric forces
acting on the trapped atoms.Comment: 4 pages, 4 figure
Necrotic tumor growth: an analytic approach
The present paper deals with a free boundary problem modeling the growth
process of necrotic multi-layer tumors. We prove the existence of flat
stationary solutions and determine the linearization of our model at such an
equilibrium. Finally, we compute the solutions of the stationary linearized
problem and comment on bifurcation.Comment: 14 pages, 3 figure
Evidence for West Nile Virus and Usutu Virus Infections in Wild and Resident Birds in Germany, 2017 and 2018
Wild birds play an important role as reservoir hosts and vectors for zoonotic arboviruses and foster their spread. Usutu virus (USUV) has been circulating endemically in Germany since 2011, while West Nile virus (WNV) was first diagnosed in several bird species and horses in 2018. In 2017 and 2018, we screened 1709 live wild and zoo birds with real-time polymerase chain reaction and serological assays. Moreover, organ samples from bird carcasses submitted in 2017 were investigated. Overall, 57 blood samples of the live birds (2017 and 2018), and 100 organ samples of dead birds (2017) were positive for USUV-RNA, while no WNV-RNA-positive sample was found. Phylogenetic analysis revealed the first detection of USUV lineage Europe 2 in Germany and the spread of USUV lineages Europe 3 and Africa 3 towards Northern Germany. USUV antibody prevalence rates were high in Eastern Germany in both years. On the contrary, in Northern Germany, high seroprevalence rates were first detected in 2018, with the first emergence of USUV in this region. Interestingly, high WNV-specific neutralizing antibody titers were observed in resident and short-distance migratory birds in Eastern Germany in 2018, indicating the first signs of a local WNV circulation
The combination of X-ray crystallography and cryo-electron microscopy provides insight into the overall architecture of the dodecameric Rvb1/Rvb2 complex
The Rvb1/Rvb2 complex is an essential component of many cellular pathways. The Rvb1/Rvb2 complex forms a dodecameric assembly where six copies of each subunit form two heterohexameric rings. However, due to conformational variability, the way the two rings pack together is still not fully understood. Here, we present the crystal structure and two cryo-electron microscopy reconstructions of the dodecameric, full-length Rvb1/Rvb2 complex, all showing that the interaction between the two heterohexameric rings is mediated through the Rvb1/Rvb2-specific domain II. Two conformations of the Rvb1/Rvb2 dodecamer are present in solution: a stretched conformation also present in the crystal, and a compact conformation. Novel asymmetric features observed in the reconstruction of the compact conformation provide additional insight into the plasticity of the Rvb1/Rvb2 complex
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