104 research outputs found
Myths and Realities about Online Forums in Open Source Software Development: An Empirical Study
The use of free and open source software (OSS) is gaining momentum due to the
ever increasing availability and use of the Internet. Organizations are also
now adopting open source software, despite some reservations, in particular
regarding the provision and availability of support. Some of the biggest
concerns about free and open source software are post release software defects
and their rectification, management of dynamic requirements and support to the
users. A common belief is that there is no appropriate support available for
this class of software. A contradictory argument is that due to the active
involvement of Internet users in online forums, there is in fact a large
resource available that communicates and manages the provision of support. The
research model of this empirical investigation examines the evidence available
to assess whether this commonly held belief is based on facts given the current
developments in OSS or simply a myth, which has developed around OSS
development. We analyzed a dataset consisting of 1880 open source software
projects covering a broad range of categories in this investigation. The
results show that online forums play a significant role in managing software
defects, implementation of new requirements and providing support to the users
in open source software and have become a major source of assistance in
maintenance of the open source projects
Antimicrobial resistance of isolated Streptococcus pneumoniae in a hospital of the Brazilian public system
Streptococcus pneumoniae is the predominant bacterial agent that affects the human population with pneumonia. This disease is an important cause of death in the elderly and the children under five years old. in this study, 29 strains of invasive S. pneumoniae were isolated from 29 patients of pneumonia, bacteremia and meningitis in the laboratory of the Municipal Hospital in Paulinia, Brazil, from May 2006 to October 2007. Patients' age ranged from 8 months old to 60 years old. These strains of S. pneumoniae were isolated from blood, pleural fluid and cerebrospinal fluid (CSF) of patients. After typing of encapsulated strains of S. pneumoniae through quellung reaction, their resistance to antimicrobial agents was gauged through Disc Diffusion Technique followed by determination of minimum inhibitory concentration (MIC). Among the 29 strains analyzed, 23 were methicillin-sensitive and six were methicillin-resistant and penicillin intermediate resistant. No strain presented full resistance to penicillin. Serotyping was performed only in two samples, which belonged to serotype 18. Our data may alert ambulatory regarding the incidence of pneumococcal strains resistant to the most common drugs due to inappropriate use of antimicrobials and also collaborate to the elaboration of pneumococcal conjugate vaccines specific to each region.NEPASHosp Municipal Paulinia, Setor Microbiol, Paulinia, SP, BrazilUniversidade Federal de São Paulo, Dept Farm Bioquim, Diadema, SP, BrazilFac Med ABC, Dept Morfol Fisiol, Lab Escrita Cientif, Santo Andre, BrazilUniv Estadual Paulista, Fac Filosofia & Ciencias, Dept Fonoaudiol, Marilia, SP, BrazilUniversidade Federal de São Paulo, Dept Farm Bioquim, Diadema, SP, BrazilWeb of Scienc
Research Blogging: Indexing and Registering the Change in Science 2.0
Increasing public interest in science information in a digital and 2.0 science era promotes a dramatically, rapid and deep change in science itself. The emergence and expansion of new technologies and internet-based tools is leading to new means to improve scientific methodology and communication, assessment, promotion and certification. It allows methods of acquisition, manipulation and storage, generating vast quantities of data that can further facilitate the research process. It also improves access to scientific results through information sharing and discussion. Content previously restricted only to specialists is now available to a wider audience. This context requires new management systems to make scientific knowledge more accessible and useable, including new measures to evaluate the reach of scientific information. The new science and research quality measures are strongly related to the new online technologies and services based in social media. Tools such as blogs, social bookmarks and online reference managers, Twitter and others offer alternative, transparent and more comprehensive information about the active interest, usage and reach of scientific publications. Another of these new filters is the Research Blogging platform, which was created in 2007 and now has over 1,230 active blogs, with over 26,960 entries posted about peer-reviewed research on subjects ranging from Anthropology to Zoology. This study takes a closer look at RB, in order to get insights into its contribution to the rapidly changing landscape of scientific communication
The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2
Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age 6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score 652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701
IBIS – Interoperability in Business Information Systems Maturity Assessment Framework for Business Dimension of Software Product Family
Abstract: The software product family approach aims at curtailing the concept of “reinventing the wheel ” in the software development process. The business has been highlighted as one of the critical dimensions in the process of software product family. This work presents an assessment framework for evaluating the business dimension of software product family process. Additionally, a software product family business evaluation tool has been designed and implemented on the basis of the presented framework. The tool preprocesses the data of key business factors, and it evaluates the overall business maturity of an organization. To demonstrate the application of the framework, and to determine the current software product family business performance, we conducted a case study of an organization actively involved in the business of software product family. The framework and the tool provide direct mechanisms to evaluate the current maturity level of software product family business of an organization. This research is a contribution towards establishing a comprehensive and unified strategy for a process evaluation of the software product family
Hypermedia Synchronization: Modeling and Optimization with Graphs
This article presents the modeling and optimization methods for a new kind of synchronization problems arising in the field of hypermedia presentations. It is shown that they can be seen as tension problems in graphs. Two of them are described in detail: the minimum cost tension problem and its discrete cost counterpart. The former is solved with pseudo-polynomial or polynomial methods. The latter is NP-complete and we discuss ways to improve its minimal and maximal objective bounds
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