Erscheinungsformen und Handhabungen Heiliger Schriften

This study focuses on Holy Scriptures as material objects. What are the contexts for the appearances and the usages of these objects? Is there a difference between Holy Scriptures and other objects, and is it inevitably their sacred content that renders them holy? Interdisciplinary perspectives offer new incentives for understanding the material phenomenon of the ‘Holy Scriptures’

A Crossover Trial Using High‐Fidelity Cardiovascular Phenotyping

Background Sympathetic and parasympathetic influences on heart rate (HR), which are governed by baroreflex mechanisms, are integrated at the cardiac sinus node through hyperpolarization‐activated cyclic nucleotide–gated channels (HCN4). We hypothesized that HCN4 blockade with ivabradine selectively attenuates HR and baroreflex HR regulation, leaving baroreflex control of muscle sympathetic nerve activity intact. Methods and Results We treated 21 healthy men with 2×7.5 mg ivabradine or placebo in a randomized crossover fashion. We recorded electrocardiogram, blood pressure, and muscle sympathetic nerve activity at rest and during pharmacological baroreflex testing. Ivabradine reduced normalized HR from 65.9±8.1 to 58.4±6.2 beats per minute (P<0.001) with unaffected blood pressure and muscle sympathetic nerve activity. On ivabradine, cardiac and sympathetic baroreflex gains and blood pressure responses to vasoactive drugs were unchanged. Ivabradine aggravated bradycardia during baroreflex loading. Conclusions HCN4 blockade with ivabradine reduced HR, leaving physiological regulation of HR and muscle sympathetic nerve activity as well as baroreflex blood pressure buffering intact. Ivabradine could aggravate bradycardia during parasympathetic activation

Ocorrência de eventos adversos em Unidade de Terapia Intensiva Neopediátrica

Background and Objectives: Technological advances enabled the creation of new specialties in health and great evolution of medical and nursing care. This study aims to analyze adverse events (AEs) in aneopediatric Intensive Care Unit as related to the these patients’ vulnerability. Methods: cross-sectional study conducted through an active search for records of Neonatal/Pediatric Nursing Intensive Care Unit at a teaching hospital from Santa Cruz do Sul, in 2014. The data collection was performed daily through the medical records where we collected the month and number of hospitalizations, the age of the neonate (in weeks) or pediatric (in years) and the AEs of each patient. Results: During the period from January to December 2014, 190 newborns were hospitalized at the Neonatal / Pediatric ICU, of which the stay rate was 0.52 patients / day; 73 AEs occurred mainly in the months of January and June, both with 10 cases (13.7%). The most frequent type of AEs is the loss of PICC 18 occurrences (25%), as well as Phlebitis with 12 occurrences (16%). Conclusion: We found a high rate of AEs, with IPCC and phlebitis being the most prevalent in the Neonatal / Pediatric ICU.Justificación y objetivo: El avance tecnológico posibilitó la creación de nuevas especialidades en la salud y gran evolución de los cuidados médicos y de enfermería. Este estudio tiene como objetivo analizar la ocurrencia de eventos adversos (EAs) en una Unidad de Terapia Intensiva Neopediátrica y relacionarlos con la vulnerabilidad a la que estos pacientes están expuestos. Métodos: Estudio epidemiológico transversal realizado por medio de búsqueda activa en registros de Enfermería de la Unidad de Terapia Intensiva Neonatal / Pediátrica de un Hospital de Enseñanza ubicado en la ciudad de Santa Cruz del Sur, durante el año 2014. La recolección de datos fue realizada diariamente a través de los prontuarios donde recolectamos mes y cantidad de internaciones, edad del neonato (en semanas) o pediátrico (en años) y los EAs de cada paciente. Resultados: En el período de enero a diciembre de 2014, en la UTI Neonatal / Pediátrica, se ingresaron 190 neonatos, de los cuales la tasa de permanencia fue de 0,52 pacientes / día, hubo ocurrencia de 73 EAs principalmente en los meses de enero y junio, ambos con 10 casos (13,7%). En cuanto al tipo de EA más frecuente, se destaca la pérdida de PICC 18 ocurrencias (25%), así como la Flebite con 12 ocurrencias (16%). Conclusión: Encontramos una elevada tasa de EAs, siendo la PICC y la flebitis las más prevalentes en la UTI Neonatal / Pediátrica.Justificativa e objetivo: O avanço tecnológico possibilitou a criação de novas especialidades na saúde e grande evolução dos cuidados médicos e de enfermagem. Este estudo tem como objetivo analisar ocorrência de eventos adversos (EAs) em uma Unidade de Terapia Intensiva Neopediátrica e relacioná-los com a vulnerabilidade as quais estes pacientes estão expostos. Métodos: Estudo epidemiológico transversal realizado por meio de busca ativa em registros de Enfermagem da Unidade de Terapia Intensiva Neonatal/Pediátrica de um Hospital de Ensino localizado na cidade de Santa Cruz do Sul, durante o ano de 2014. A coleta de dados foi realizada diariamente através dos prontuários onde coletamos mês e quantidade de internações, idade do neonato (em semanas) ou pediátrico (em anos) e os EAs de cada paciente. Resultados: No período de janeiro a dezembro de 2014, na UTI Neonatal/Pediátrica, foram internados 190 neonatos, dos quais a taxa de permanência foi de 0,52 pacientes/dia, houve ocorrência de 73 EAs principalmente nos meses de janeiro e junho, ambos com 10 casos (13,7%). Quanto ao tipo de EA mais frequente, destaca-se a perda de PICC 18 ocorrências (25%), bem como a Flebite com 12 ocorrências (16%). Conclusão: Encontramos uma elevada taxa de EAs, sendo a PICC e a flebite as mais prevalentes na UTI Neonatal/Pediátrica

INTEGRATION OF TRANSPORT LOGISTICS HUBS IN FREIGHT TRANSPORT DEMAND MODELLING

Changes in transport logistics result in changes in freight transport. Therefore, logistics is seen as being of major importance and a driver for the development of freight transport itself. In freight transport demand modelling the mapping of logistics-caused influences on freight transport emerged as an important topic in this context, too. Logistics aspects found more and more consideration in modelling in last decades. Nevertheless, there are some essential aspects that are covered insufficiently by models, especially for the German context. One of these aspects is the consideration of transport logistics hubs – hubs that do not have storage function (although there may be a certain buffer capacity due to the transhipment process). Transport logistics hubs are of great importance in transport logistics today because transport is increasingly managed and handled at these hubs. Thus, they have a significant influence on generation of freight transport. They play a crucial role for transport processes because commodity flows are bundled and concentrated at these points. Nonetheless, transport logistics hubs (e.g. locations of forwarding companies, combined transport terminals) are hardly integrated in freight transport demand modelling and rarely covered empirically, as well. Due to the fact that all demand models need proper input to integrate transport logistics hubs adequately, the lack of data represents a major challenge here. In order to close this gap a project, funded by the German Research Foundation (DFG), was launched. First of all, a typological order of hubs was developed by reviewing hub specific literature. In this manner, different attributes and characteristic values were identified. They served as a basis for an empirical survey. Additionally, a comprehensive literature review examined national and international freight transport demand models due to their integration of transport logistics hubs. Data requirements as well as transferability of modelling approaches were reviewed in this context. In a second step, a huge secondary data pool was compiled by investigating all hub locations in Germany and their specific data. These data mainly concentrate on transport statistics and company data. The following data acquisition (survey) focussed on the identified hubs and companies from the previous secondary data analysis. Thirdly, statistical analysis (e.g. non-linear regression analysis) helped to determine correlations between key parameters of the surveyed hubs. Using the discovered correlations, secondary and primary data were linked in order to provide input parameter for the modelling process. In the last step we developed an approach to integrate transport logistics hub into freight transport demand modelling. The aim of the article is to present the major findings and results of the project. We will present an integrated approach to consider transport logistics hubs, its typological derivation of statistical values according to their transport generation as well as the modelling approach that considers transport logistics hubs. The literature review mainly showed that only some of them consider transport logistics hubs in an adequate way. Logistics hubs are mostly considered as distribution logistics hubs, whereas transport logistics hubs, if considered, are commonly integrated as simple sources/sinks or so called special generators. This procedure is, however, not suitable for all types of hubs. In order to integrate transport logistics hubs for the area of Germany in an adequate way, there is a need to survey hub specific data. The carried out typological classification of transport hubs will present all types of hubs, which were identified and considered in the further analysis steps (e.g. ports for international and inland waterways, terminals of combined freight transport, airports, freight transport centres, locations of KEP-service provider and freight forwarders). The compiled data pool of logistics hubs and companies includes nearly 2.400 contacts and focusses especially on the 14 freight forwarding networks in Germany dealing with general cargo. All returned answers of the survey – almost 400 – provide detailed hub specific information regarding its characteristics (e.g. handling area, transport volume and trips, used vehicles, clients’ business sectors, etc.). Findings of the non-linear regression analysis show that there are significant correlations between key parameters and hub characteristics. This will be exemplified in the article for hubs corresponding to freight forwarders and other facilities of goods transportation in the road transport sector. Using these correlations we will present possibilities to integrate the gathered knowledge of transport logistic hubs into freight transport demand modelling as well as a concept to reproduce the hub specific freight transport demand – explicitly for the case of freight forwarding companies. Furthermore, an outlook to the further use of the gathered information (e.g. development of a logistics module) will close the paper

Electric Vehicles for Urban Logistics and Commercial Transport – User Needs and Obstacles

Commercial transport and logistics constitutes 30% and more of transport related emissions in cities today already and it is expected, that these forms of traffic will increase in the future due to the urbanisation trend. In order to reduce local emissions, electromobility for urban logistics is presenting itself as an interesting alternative to conventional, combustion engine powered vehicles. Based on empirical research in form of an online survey, using the example of Berlin, Germany, this research identifies potential user groups for electromobility for urban logistics and their transport demand characteristics. It analyses their needs and requirements regarding electric vehicles for urban logistics and compares them to needs and concerns as perceived by potential users. Findings are complemented and validated with data extracted from other transport surveys, namely the KiD Kraftfahrzeugverkehr in Deutschland 2010, which contains 115,000 trips of about 70,000 vehicles. The text closes with an overview on user groups within the context of urban deliveries for whom a shift to electromobility is more within reach as well as an overview on the most frequently encountered obstacles when analyzing shifting potential for urban logistics

Nutzerprofile der Elektromobilität im urbanen Wirtschaftsverkehr

Im Rahmen der Veranstaltungsreihe "Schaufenster on Tour" der Agentur für Elektromobilität eMO wurde das Projekt Smart e-User vorgestellt. Mit dem Vortrag zum Thema "Nutzerprofile der Elektromobilität im Wirtschaftsverkehr" wurden die Ergebnisse der im Rahmen des Projekts gemachten qualitativen und quantitativen Erhebungen zu Nutzeranforderungen an Elektrofahrzeuge im Wirtschaftsverkehr am Beispiel von Berlin vorgestellt. Die Ergebnisse dieser Erhebung wurden darüber hinaus mithilfe einer Analyse der KiD 2010 Daten überprüft, um so mögliche Nutzerprofile für den Einsatz von Elektrofahrzeugen im Wirtschaftsverkehr zu identifizieren und die Markthochlaufphase der e-Mobilität gezielt unterstützen zu können