The Nurses’ Perception of Expressive Touch: An Integrative Review

Introduction: Nurses use physical touch to interact with patients and address their needs. Human touch benefits social development, stress/anxiety reduction, and rapport building. Touch has been a part of nursing care for centuries, however nurses’ perceptions of expressive touch are not easily ascertained from the literature. Literature currently offers one review on the perceptions of various medical professionals regarding touch of all kinds. No reviews specific to the nurses’ perception of expressive touch exist. This integrative review provides a greater understanding of nurses’ perceptions of expressive touch. Methods: Using Cooper’s steps for integrative review, CINAHL, Medline, Academic Search Premier, and Complimentary Index were searched from 2000-2022; using search term expressive touch or caring touch or compassionate touch and nurse/nurses/nursing and perception or perspective. Results: Of 283 articles identified, 22 articles remained for full-text review after duplicate removal and application of inclusion/exclusion criteria. Five topics on nurses’ perceptions of expressive touch were identified: Comfort with touch and job satisfaction, expressive touch as an essential part of nursing practice, expressive touch as a form of compassion and/or communication, the impact of expressive touch on the humanization of patients in the nurses’ perception, and nurse discomfort with expressive touch. Conclusion: This integrative review provides findings that assist in understanding nurses’ perceptions of expressive touch. Further research should examine the impact of gender, education, and experiences on nurses’ perceptions as they use expressive touch in nursing practice

Use of Patient-Reported Outcomes to Understand & Measure the Patient Experience of Novel Cell and Gene Therapies

Patient reported outcomes (PROs) are the gold standard for assessing patients’ experience of treatment in oncology, defined in the 21st Century Cures Act as information about patients’ experiences with a disease or condition, including the impact of a disease or condition, or a related therapy or clinical investigation on patients’ lives; and patient preferences with respect to treatment of their disease or condition [1]. PROs provide a comprehensive assessment of the benefits and risks of new medical products, as well as essential data to inform real-world use. Although RCTs are the ultimate source for information for evaluating products in development, they are not always feasible for rare diseases with few or no effective treatment options available. Thus, it is important to consider other measures that can help to improve the strength of evidence for cell and gene therapies targeting rare indications. While collection of PROs and other patient experience endpoints does not resolve the difficulty of conducting trials in small populations, doing so contributes empirical evidence that informs both product development and patient access. Additionally, including routine collection of PROs in registries may provide supplemental data to further characterize the benefit:risk profile of cell and gene therapies at follow-up times that would be infeasible to operationalize in a clinical trial setting

Neuropathic pain in a rehabilitation setting after spinal cord injury: an interpretative phenomenological analysis of inpatients’ experiences

Study design Qualitative, semi-structured interviews. Objectives Neuropathic pain (NP) can be psychologically and physically debilitating, and is present in approximately half of the spinal cord injured (SCI) population. However, under half of those with NP are adherent to pain medication. Understanding the impact of NP during rehabilitation is required to reduce long-term impact and to promote adherence to medication and psychoeducation recommendations. Setting United Kingdom. Methods Five males and three females with SCI and chronic NP, resident in rehabilitation wards at a specialist SCI center in the United Kingdom, took part. Semi-structured interviews were conducted with participants less than 15 months post-SCI (mean = 8.4 months). Verbatim transcripts were subject to interpretative phenomenological analysis (IPA). Results Three super-ordinate themes were identified, mediating pain and adherence: (1) the dichotomy of safety perceptions; (2) adherence despite adversity; and (3) fighting the future. Analyses suggest that experience of the rehabilitation setting and responsiveness of care shapes early distress. Attitudes to medication and psychosocial adjustment are relevant to developing expectations about pain management. Conclusions Enhancing self-efficacy, feelings of safety in hospital, and encouraging the adoption of adaptive coping strategies may enhance psychosocial and pain-related outcomes, and improve adherence to medication. Encouraging adaptive responses to, and interpretation of, pain, through the use of interventions such as coping effectiveness training, targeted cognitive behavioral pain management, and acceptance-based interventions such as mindfulness, is recommended in order to reduce long-term reliance on medication

Early GABA(A) receptor clustering during the development of the rostral nucleus of the solitary tract

While there is an abundance of gamma-aminobutyric acid (GABA) in the gustatory zone of the nucleus of the solitary tract of the perinatal rat, we know that GABAergic synapse formation is not complete until well after birth. Our recent results have shown that GABA(B) receptors are present at birth in the cells of the nucleus; however, they do not redistribute and cluster at synaptic sites until after PND10. The present study examined the time course of appearance and redistribution of GABA(A) receptors in the nucleus. GABA(A) receptors were also present at birth. However, in comparison to GABA(B) receptors, GABA(A) receptors underwent an earlier translocation to synaptic sites. Extrasynaptic label, for example, of GABA(A) receptors was non-existent compared to GABA(B) receptors at PND10 and well-defined clusters of GABA(A) receptors could be seen as early as PND1. We propose that while GABA(A) receptors may play an early neurotransmitter role at the synapse, GABA(B) receptors may play a non-transmitter neurotrophic role