984 research outputs found
Adaptation to the Edge of Chaos in the Self-Adjusting Logistic Map
Self-adjusting, or adaptive systems have gathered much recent interest. We
present a model for self-adjusting systems which treats the control parameters
of the system as slowly varying, rather than constant. The dynamics of these
parameters is governed by a low-pass filtered feedback from the dynamical
variables of the system. We apply this model to the logistic map and examine
the behavior of the control parameter. We find that the parameter leaves the
chaotic regime. We observe a high probability of finding the parameter at the
boundary between periodicity and chaos. We therefore find that this system
exhibits adaptation to the edge of chaos.Comment: 3 figure
Effect of Chaotic Noise on Multistable Systems
In a recent letter [Phys.Rev.Lett. {\bf 30}, 3269 (1995), chao-dyn/9510011],
we reported that a macroscopic chaotic determinism emerges in a multistable
system: the unidirectional motion of a dissipative particle subject to an
apparently symmetric chaotic noise occurs even if the particle is in a
spatially symmetric potential. In this paper, we study the global dynamics of a
dissipative particle by investigating the barrier crossing probability of the
particle between two basins of the multistable potential. We derive
analytically an expression of the barrier crossing probability of the particle
subject to a chaotic noise generated by a general piecewise linear map. We also
show that the obtained analytical barrier crossing probability is applicable to
a chaotic noise generated not only by a piecewise linear map with a uniform
invariant density but also by a non-piecewise linear map with non-uniform
invariant density. We claim, from the viewpoint of the noise induced motion in
a multistable system, that chaotic noise is a first realization of the effect
of {\em dynamical asymmetry} of general noise which induces the symmetry
breaking dynamics.Comment: 14 pages, 9 figures, to appear in Phys.Rev.
Illocutionary harm
A number of philosophers have become interested in the ways that individuals are subject to harm as the performers of illocutionary acts. This paper offers an account of the underlying structure of such harms: I argue that speakers are the subjects of illocutionary harm when there is interference in the entitlement structure of their linguistic activities. This interference comes in two forms: denial and incapacitation. In cases of denial, a speaker is prevented from achieving the outcomes to which they are entitled by their speech. In cases of incapacitation, a speaker’s standing to expect certain outcomes is itself undermined. I also discuss how individual speakers are subject to interference along two dimensions: as exercisers of certain non-linguistic capacities, and as producers of meaningful speech
Quality-of-life issues and symptoms reported by patients living with haematological malignancy: a qualitative study
Background: Our aim was to identify health-related quality-of-life (HRQoL) issues and symptoms in patients with haematological malignancies (HMs) and develop a conceptual framework to reflect the inter-relation between them. /
Methods: A total of 129 patients with HMs were interviewed in a UK multicentre qualitative study. All interviews were audio recorded, transcribed and analysed using NVivo-11. /
Results: Overall, 34 issues were reported by patients and were grouped into two parts: quality of life (QoL) and symptoms. The most prevalent HRQoL issues were: eating and drinking habits; social life; physical activity; sleep; and psychological well-being. Furthermore, most prevalent disease-related symptoms were: tiredness; feeling unwell; breathlessness; lack of energy; and back pain. The most prevalent treatment side effects were: tiredness; feeling sick; disturbance in sense of taste; and breathlessness. /
Conclusions: Both HMs and their treatments have a significant impact on patients’ HRQoL, in particular on issues such as job-role change, body image and impact on finances
Three-dimensional atmospheric circulation of hot Jupiters on highly eccentric orbits
Of the over 800 exoplanets detected to date, over half are on non-circular
orbits, with eccentricities as high as 0.93. Such orbits lead to time-variable
stellar heating, which has implications for the planet's atmospheric dynamical
regime. However, little is known about this dynamical regime, and how it may
influence observations. Therefore, we present a systematic study of hot
Jupiters on highly eccentric orbits using the SPARC/MITgcm, a model which
couples a three-dimensional general circulation model with a plane-parallel,
two-stream, non-grey radiative transfer model. In our study, we vary the
eccentricity and orbit-average stellar flux over a wide range. We demonstrate
that the eccentric hot Jupiter regime is qualitatively similar to that of
planets on circular orbits; the planets possess a superrotating equatorial jet
and exhibit large day-night temperature variations. We show that these
day-night heating variations induce momentum fluxes equatorward to maintain the
superrotating jet throughout its orbit. As the eccentricity and/or stellar flux
is increased, the superrotating jet strengthens and narrows, due to a smaller
Rossby deformation radius. For a select number of model integrations, we
generate full-orbit lightcurves and find that the timing of transit and
secondary eclipse viewed from Earth with respect to periapse and apoapse can
greatly affect what we see in infrared (IR) lightcurves; the peak in IR flux
can lead or lag secondary eclipse depending on the geometry. For those planets
that have large day-night temperature variations and rapid rotation rates, we
find that the lightcurves exhibit "ringing" as the planet's hottest region
rotates in and out of view from Earth. These results can be used to explain
future observations of eccentric transiting exoplanets.Comment: 20 pages, 18 figures, 2 tables; Accepted to Ap
Opposing offspring sex ratio variations with increasing age and weight in mouflon mothers (Ovis musimon)
There are two main theories explaining offspring sex biases in polygynous mammals. Trivers and Willard (1973) argue that mothers with greater reproductive resources should invest in the sex with the greater variance in reproductive success, usually sons. In contrast, because daughters in many polygynous mammals stay with their mother and compete with her for food, Local Resource Competition theory (e.g. Clark, 1978; Silk, 1983) predicts that the mothers with the greatest reproductive resources should invest in daughters. We investigated the strategy of sex allocation of a captive, outdoor population of 139 mouflon mothers, Ovis musimon, kept in a game state. A complex picture emerged in which, despite weight and body condition being correlated with age in female mouflons, mothers lambed more daughters with increasing age but also, within a given age, gave birth to more sons with increasing weight. Results may be useful in game management aimed at increasing the recruitment or quality o f males in managed populations
Development of a Novel Hematological Malignancy Specific Patient-Reported Outcome Measure (HM-PRO) : Content Validity
Copyright © 2020 Goswami, Oliva, Ionova, Else, Kell, Fielding, Jennings, Karakantza, Al-Ismail, Collins, McConnell, Langton and Salek.Background: The quality of life of patients at all stages of hematological malignancy is greatly affected by the disease and its treatment. There is a wide range of health-related quality of life (HRQoL) issues important to these patients. Any new instrument developed to measure HRQoL of such patients should be content valid, i.e., the items should be comprehensively relevant to the patients and their health condition. The aim of the present study was to examine content validity of a hematological malignancy specific patient reported outcome measure (HM-PRO) developed for use in routine clinical practice. Methods: Following literature review and semi-structured interviews, the generated themes and sub-themes were discussed to develop the prototype version of the HM-PRO. A 4-step approach was used for content validation: initial testing and cognitive interviewing; item rating; content validity panel meeting; final field testing and cognitive interviewing. Additional questions related to patients' perception of recall period and preferred sentence structure (i.e., question or statement) of the items were also asked during cognitive interviews. Results: The content analysis of 129 transcribed semi-structured interviews resulted in the prototype version of the instrument consisting of 58 items grouped into two parts: Part A (impact/HRQoL - 34 items) and Part B (signs and symptoms - 24 items). The initial testing showed intra-class correlation coefficient (ICC) of >0.8 for both Part A and Part B. Item rating for language clarity, completeness, relevance, and response scale by experts and patients showed content validity index for scales average >0.8 for both Part A and Part B, except 0.64 for relevance for Part A by the patient panel. The final testing of the revised version of the instrument showed the Cronbach's alpha value of 0.91 for Part A and 0.76 for Part B, suggesting high internal consistency, and ICC of 0.91 for Part A and 0.76 for Part B. The recall period of "today" for Part-A and "last 3 days" for Part-B were the patients' preferred "recall period." Furthermore, the patients expressed preference to the HM-PRO items as statements. Conclusion: The findings of this study confirm that the HM-PRO possesses a strong content validity, includes all the issues important to patients and is easy to read, understand and respond to spontaneously.Peer reviewedFinal Published versio
Avalanches in self-organized critical neural networks: A minimal model for the neural SOC universality class
The brain keeps its overall dynamics in a corridor of intermediate activity
and it has been a long standing question what possible mechanism could achieve
this task. Mechanisms from the field of statistical physics have long been
suggesting that this homeostasis of brain activity could occur even without a
central regulator, via self-organization on the level of neurons and their
interactions, alone. Such physical mechanisms from the class of self-organized
criticality exhibit characteristic dynamical signatures, similar to seismic
activity related to earthquakes. Measurements of cortex rest activity showed
first signs of dynamical signatures potentially pointing to self-organized
critical dynamics in the brain. Indeed, recent more accurate measurements
allowed for a detailed comparison with scaling theory of non-equilibrium
critical phenomena, proving the existence of criticality in cortex dynamics. We
here compare this new evaluation of cortex activity data to the predictions of
the earliest physics spin model of self-organized critical neural networks. We
find that the model matches with the recent experimental data and its
interpretation in terms of dynamical signatures for criticality in the brain.
The combination of signatures for criticality, power law distributions of
avalanche sizes and durations, as well as a specific scaling relationship
between anomalous exponents, defines a universality class characteristic of the
particular critical phenomenon observed in the neural experiments. The spin
model is a candidate for a minimal model of a self-organized critical adaptive
network for the universality class of neural criticality. As a prototype model,
it provides the background for models that include more biological details, yet
share the same universality class characteristic of the homeostasis of activity
in the brain.Comment: 17 pages, 5 figure
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