Interpreting the photometry and spectroscopy of directly imaged planets: a new atmospheric model applied to beta Pictoris b and SPHERE observations

We aim to interpret future photometric and spectral measurements from these instruments, in terms of physical parameters of the planets, with an atmospheric model using a minimal number of assumptions and parameters. We developed Exoplanet Radiative-convective Equilibrium Model (Exo-REM) to analyze the photometric and spectro- scopic data of directly imaged planets. The input parameters are a planet's surface gravity (g), effective temperature (Teff ), and elemental composition. The model predicts the equilibrium temperature profile and mixing ratio profiles of the most important gases. Opacity sources include the H2-He collision-induced absorption and molecular lines from eight compounds (including CH4 updated with the Exomol line list). Absorption by iron and silicate cloud particles is added above the expected condensation levels with a fixed scale height and a given optical depth at some reference wavelength. Scattering was not included at this stage. We applied Exo-REM to photometric and spectral observations of the planet beta Pictoris b obtained in a series of near-IR filters. We derived Teff = 1550 +- 150 K, log(g) = 3.5 +- 1, and radius R = 1.76 +- 0.24 RJup (2-{\sigma} error bars from photometric measurements). These values are comparable to those found in the literature, although with more conservative error bars, consistent with the model accuracy. We were able to reproduce, within error bars, the J- and H-band spectra of beta Pictoris b. We finally investigated the precision to which the above parameterComment: 15 pages, 14 figures, accepted by A&

Optimization of Laser-Induced Graphene Electrodes for High Voltage and Highly Stable Microsupercapacitors

Microsupercapacitors (μSCs) have received a lot of interest for their possible use in miniaturized electronics and in the field of the Internet of Things (IoT) to power distributed sensors. μSCs fill the gap between batteries and traditional capacitors, providing high power densities and acceptable energy densities to fulfill onboard power supply requirements, coupled with quick charge/discharge rates and extended lifetime. Charge balancing of μSCs is not a standard practice, although the optimization of electrodes can provide beneficial effects on the electrochemical performance and stability of the device. In this work, a charge-balanced double-layer μSC based on laser-induced graphene (LIG) with [PYR14][TFSI] as an ionic liquid electrolyte is presented for the first time. The optimized device shows an improvement in terms of the increased lifetime of a factor of four and its energy efficiency is raised above 80%

Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1low Monocytes

Monocytes are heterogeneous effector cells involved in the maintenance and restoration of tissue integrity. However, their response to hyperlipidemia remains poorly understood. Here, we report that in the presence of elevated levels of triglyceride-rich lipoproteins, induced by administration of poloxamer 407, the blood numbers of non-classical Ly6C/Gr1(low) monocytes drop, while the number of bone marrow progenitors remains similar. We observed an increased crawling and retention of the Gr1(low) monocytes at the endothelial interface and a marked accumulation of CD68(+) macrophages in several organs. Hypertriglyceridemia was accompanied by an increased expression of tissue, and plasma CCL4 and blood Gr1(low) monocyte depletion involved a pertussis-toxin-sensitive receptor axis. Collectively, these findings demonstrate that a triglyceride-rich environment can alter blood monocyte distribution, promoting the extravasation of Gr1(low) cells. The behavior of these cells in response to dyslipidemia highlights the significant impact that high levels of triglyceride-rich lipoproteins may have on innate immune cells

Intranasal peptide-induced tolerance and linked suppression: consequences of complement deficiency.

A role for complement, particularly the classical pathway, in the regulation of immune responses is well documented. Deficiencies in C1q or C4 predispose to autoimmunity, while deficiency in C3 affects the suppression of contact sensitization and generation of oral tolerance. Complement components including C3 have been shown to be required for both B-cell and T-cell priming. The mechanisms whereby complement can mediate these diverse regulatory effects are poorly understood. Our previous work, using the mouse minor histocompatibility (HY) model of skin graft rejection, showed that both C1q and C3 were required for the induction of tolerance following intranasal peptide administration. By comparing tolerance induction in wild-type C57BL/6 and C1q-, C3-, C4- and C5-deficient C57BL/6 female mice, we show here that the classical pathway components including C3 are required for tolerance induction, whereas C5 plays no role. C3-deficient mice failed to generate a functional regulatory T (Treg) -dendritic cell (DC) tolerogenic loop required for tolerance induction. This was related to the inability of C3-deficient DC to up-regulate the arginine-consuming enzyme, inducible nitric oxide synthase (Nos-2), in the presence of antigen-specific Treg cells and peptide, leading to reduced Treg cell generation. Our findings demonstrate that the classical pathway and C3 play a critical role in the peptide-mediated induction of tolerance to HY by modulating DC function

First light of the VLT planet finder SPHERE. I. Detection and characterization of the sub-stellar companion GJ 758 B

GJ758 B is a brown dwarf companion to a nearby (15.76 pc) solar-type, metal-rich (M/H = +0.2 dex) main-sequence star (G9V) that was discovered with Subaru/HiCIAO in 2009. From previous studies, it has drawn attention as being the coldest (~600K) companion ever directly imaged around a neighboring star. We present new high-contrast data obtained during the commissioning of the SPHERE instrument at the VLT. The data was obtained in Y-, J-, H-, and Ks-bands with the dual-band imaging (DBI) mode of IRDIS, providing a broad coverage of the full near-infrared (near-IR) range at higher contrast and better spectral sampling than previously reported. In this new set of high-quality data, we report the re-detection of the companion, as well as the first detection of a new candidate closer-in to the star. We use the new 8 photometric points for an extended comparison of GJ758 B with empirical objects and 4 families of atmospheric models. From comparison to empirical object, we estimate a T8 spectral type, but none of the comparison object can accurately represent the observed near-IR fluxes of GJ758 B. From comparison to atmospheric models, we attribute a Teff = 600K $\pm$ 100K, but we find that no atmospheric model can adequately fit all the fluxes of GJ758 B. The photometry of the new candidate companion is broadly consistent with L-type objects, but a second epoch with improved photometry is necessary to clarify its status. The new astrometry of GJ758 B shows a significant proper motion since the last epoch. We use this result to improve the determination of the orbital characteristics using two fitting approaches, Least-Square Monte Carlo and Markov Chain Monte Carlo. Finally, we analyze the sensitivity of our data to additional closer-in companions and reject the possibility of other massive brown dwarf companions down to 4-5 AU. [abridged]Comment: 20 pages, 15 figures. Accepted for publication in A&

Dichotomy between T Cell and B Cell Tolerance to Neonatal Retroviral Infection Permits T Cell Therapy

Elucidation of the immune requirements for control or elimination of retroviral infection remains an important aim. We studied the induction of adaptive immunity to neonatal infection with a murine retrovirus, under conditions leading to immunological tolerance. We found that the absence of either maternal or offspring adaptive immunity permitted efficient vertical transmission of the retrovirus. Maternal immunodeficiency allowed the retrovirus to induce central Th cell tolerance in the infected offspring. In turn, this compromised the offspring’s ability to mount a protective Th cell–dependent B cell response. However, in contrast to T cells, offspring B cells were not centrally tolerized and retained their ability to respond to the infection when provided with T cell help. Thus, escape of retrovirus-specific B cells from deletional tolerance offers the opportunity to induce protective retroviral immunity by restoration of retrovirus-specific T cell help, suggesting similar T cell immunotherapies for persistent viral infections

Exoplanetary Monte Carlo radiative transfer with correlated-k - I. Benchmarking transit and emission observables

G.K.H. Lee acknowledges support from the University of Oxford and CSH Bern through the Bernoulli fellowship. G.K.H Lee acknowledges funding from the European community through the ERC project EXOCONDENSE (740963). The participants of the OWL 2018 summer program are thanked for numerous discussions and encouragement on the development of the model. J. Taylor is a Penrose Scholar and would like to thank the Oxford Physics Endowment for Graduates (OXPEG) for funding this research. J-L Baudino acknowledges the support of the UK Science and Technology Facilities Council.Current observational data of exoplanets are providing increasing detail of their 3D atmospheric structures. As characterization efforts expand in scope, the need to develop consistent 3D radiative-transfer methods becomes more pertinent as the complex atmospheric properties of exoplanets are required to be modelled together consistently. We aim to compare the transmission and emission spectra results of a 3D Monte Carlo radiative transfer (MCRT) model to contemporary radiative-transfer suites. We perform several benchmarking tests of an MCRT code, Cloudy Monte Carlo Radiative Transfer (CMCRT), to transmission and emission spectra model output. We add flexibility to the model through the use of k-distribution tables as input opacities. We present a hybrid MCRT and ray tracing methodology for the calculation of transmission spectra with a multiple scattering component. CMCRT compares well to the transmission spectra benchmarks at the 10s of ppm level. Emission spectra benchmarks are consistent to within 10 per cent of the 1D models. We suggest that differences in the benchmark results are likely caused by geometric effects between plane-parallel and spherical models. In a practical application, we post-process a cloudy 3D HD 189733b GCM model and compare to available observational data. Our results suggest the core methodology and algorithms of CMCRT produce consistent results to contemporary radiative transfer suites. 3D MCRT methods are highly suitable for detailed post-processing of cloudy and non-cloudy 1D and 3D exoplanet atmosphere simulations in instances where atmospheric inhomogeneities, significant limb effects/geometry or multiple scattering components are important considerations.Publisher PDFPeer reviewe

Post conjunction detection of β\beta Pictoris b with VLT/SPHERE

With an orbital distance comparable to that of Saturn in the solar system, \bpic b is the closest (semi-major axis $\simeq$\,9\,au) exoplanet that has been imaged to orbit a star. Thus it offers unique opportunities for detailed studies of its orbital, physical, and atmospheric properties, and of disk-planet interactions. With the exception of the discovery observations in 2003 with NaCo at the Very Large Telescope (VLT), all following astrometric measurements relative to \bpic have been obtained in the southwestern part of the orbit, which severely limits the determination of the planet's orbital parameters. We aimed at further constraining \bpic b orbital properties using more data, and, in particular, data taken in the northeastern part of the orbit. We used SPHERE at the VLT to precisely monitor the orbital motion of beta \bpic b since first light of the instrument in 2014. We were able to monitor the planet until November 2016, when its angular separation became too small (125 mas, i.e., 1.6\,au) and prevented further detection. We redetected \bpic b on the northeast side of the disk at a separation of 139\,mas and a PA of 30$^{\circ}$ in September 2018. The planetary orbit is now well constrained. With a semi-major axis (sma) of $a = 9.0 \pm 0.5$ au (1 $\sigma$), it definitely excludes previously reported possible long orbital periods, and excludes \bpic b as the origin of photometric variations that took place in 1981. We also refine the eccentricity and inclination of the planet. From an instrumental point of view, these data demonstrate that it is possible to detect, if they exist, young massive Jupiters that orbit at less than 2 au from a star that is 20 pc away.Comment: accepted by A&