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Enabling Operator Reordering in Data Flow Programs Through Static Code Analysis

In many massively parallel data management platforms, programs are represented as small imperative pieces of code connected in a data flow. This popular abstraction makes it hard to apply algebraic reordering techniques employed by relational DBMSs and other systems that use an algebraic programming abstraction. We present a code analysis technique based on reverse data and control flow analysis that discovers a set of properties from user code, which can be used to emulate algebraic optimizations in this setting.Comment: 4 pages, accepted and presented at the First International Workshop on Cross-model Language Design and Implementation (XLDI), affiliated with ICFP 2012, Copenhage

Connections of the corticomedial amygdala in the golden hamster. II. Efferents of the “olfactory amygdala”

The anterior cortical (C1) and posterolateral cortical (C2) nuclei of the amygdala are designated the “olfactory amygdala” because they each receive direct projections from the main olfactory bulb. The efferents of these nuclei were traced after sterotaxic placement of 1—5 ΜCi tritiated proline in the corticomedial amygdala of male golden hamsters. Following survival times of 12, 24, or 48 hours, 20 Μm frozen sections of the brains were processed for light microscopic autoradiography. Efferents from C2 terminate in layers II and III of the olfactory tubercle and in layer lb of pars ventralis and pars medialis of the anterior olfactory nucleus. Fibers from this nucleus also project to layers I and II of the infralimbic cortex and to the molecular layer of the agranular insular cortex. More posteriorly, fibers from C2 teminate in layer I of the dorsolateral entorhinal cortex, and in the endopiriform nucleus. From C1, efferent fibers travel in the stria terminalis and terminate in the precommissural bed nucleus of the stria terminalis and in the mediobasal hypothalamus. Efferents from C1 also innervate the molecular layer of C2, the amygdalo-hippocampal area, and the adjacent piriform cortex. Neurons in both C1 and C2 project to the molecular layer of the medial amygdaloid nucleus and the posteromedial cortical nucleus of the amygdala, the plexiform layer of the ventral subiculum, and the molecular layer of the lateral entorhinal cortex.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/50013/1/901970108_ftp.pd

Limb Lengthening Using the PRECICE^TM Nail System: Complications and Results

Background: Three types of telescopic nails are mainly used for intramedullary limb lengthening nowadays. Despite some important advantages of this new technology (e.g. controlled distraction rate, not restricted availability, possibility to perform accordion maneuvers), few articles exist on clinical results and complications after lengthening with the PRECICETM nail (Ellipse, USA). Objectives: The aim of the current study was to describe and analyze the complications associated with lengthening with the PRECICETM nail. Are the problems preventable when using the PRECICE, related to the distraction rate control, the lengthening goals and technique and handling? Methods: We retrospectively reviewed the charts of 9 patients operated between 2012 and 2013 with a PRECICETM nail for a leg length discrepancy (LLD). The mean age of the patients was 32 years (range, 17 - 48 years). There were 5 femoral and 4 tibial procedures. The causes of LLD were posttraumatic (n = 5) and congenital (n = 4). The mean LLD was 36.4 ± 11.4 mm. The minimum follow-ups were 2 months (average, 5 months; range, 2 - 9 months). Results: The mean distraction rate was 0.5 ± 0.1 mm/day. We observed in 7 patients differences in achieving the lengthening goals (average, 1.6 mm; range, -20.0 - 5.0 mm). Average lengthening was 34.7 ± 10.7 mm. All patients reached normal alignment and normal joint orientation. An unintentional loss of the achieved length during the consolidation phase was noticed in patients with delayed bone healing in two cases. In the first case (loss of 20mm distraction) the nail could be redistracted and the goal length was achieved. In the second case (loss of 10mm distraction) the nail broke shortly after the diagnosis and the nail was exchanged. Conclusions: We report of loss of achieved length after lengthening with a telescopic nail. Weight bearing before complete consolidation of the regenerate might be a risk factor for that. Thorough examination of the limb length and careful evaluation of the radiographs are required in the follow-up period. The PRECICE nail system requires the same vigilance like the other intramedullary systems too

Connections of the corticomedial amygdala in the golden hamster. I. Efferents of the “vomeronasal amygdala”

The medial (M) and posteromedial cortical (C3) amygdaloid nuclei and the nucleus of the accessory olfactory tract (NAOT) are disignated the “vomeronasal amygdala” because they are the only components of the amygdala to receive a direct projection from the accessory olfactory bulb (AOB). The efferents of M and C3 were traced after injections of 3 H-proline into the amygdala in male golden hamsters. Frozen sections of the brains were processed for autoradiography. The efferents of the “vomeronasal amygdala” are largely to areas which are primary and secondary terminal areas along the vomeronasal pathway, although the efferents from C3 and M terminate in different layers in these areas than do the projections from the vomeronasal nerve or the AOB. Specifically, C3 projects ipsilaterally to the internal granule cell layer of the AOB, the cellular layer of NAOT, and layer lb of M. Additional fibers from C3 terminate in a retrocommissural component of the bed nucleus of the stria terminalis (BNST) bilaterally, and in the cellular layers of the contralateral C3. The medial nucleus projects to the cellular layer of the ipsilateral NAOT, layer lb of C3, and bilaterally to the medial component of BNST. Projections from M to non-vomeronasal areas terminate in the medial preoptic area-anterior hypothalamic junction, ventromedial nucleus of the hypothalamus, ventral premammillary nucleus and possibly in the ventral subiculum. These results demonstrate reciprocal connections between primary and secondary vomeronasal areas and between the secondary areas themselves. They suggest that M, but not C3, projects to areas outside this vomeronasal network. The medial amygdaloid nucleus is therefore an important link between the vomeronasal organ and areas of the brain not receiving direct vomeronasal input.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/50012/1/901970107_ftp.pd

Identification of new emerging pollutants in surface water using suspect screening analysis and prioritisation strategies based on regulatory databases

Emerging pollutants (EP) have the potential to enter the water system and cause adverse ecological and human health effects while simultaneously not being covered by existing water-quality regulations. However, the existing target analysis methodology only allows the detection of a very small fraction of the substances present in wastewater samples. The new advances in high resolution mass spectrometry (HRMS) and the application of suspect screening, with a suspected screening list based on prior information but with no reference standard, greatly increases the list of substances that can be identified. The present study aims to detect and identify new, potentially hazardous pollutants based on the hypothesis that regulatory databases can assist in the prioritisation of relevant substances. Data from the Swedish Chemical Agency was used to prioritise compounds based on the occurrence on the market, the consumer tonnages, and the use pattern, among other factors. Out of the approximately 20 000 chemicals present in the database, 143 potential organic pollutants were prioritised and a screening was performed in surface water from different locations in Sweden using a LC-HRMS-based analytical approach. 21 tentative identifications were successfully performed with most substances being formerly out of the focus for environmental scientists (also not included in regulations nor monitoring programs). 16 of those substances were further confirmed with reference standard (the highest number in a study of this nature) showing the efficiency of both, the prioritisation strategy, and the suspect screening approach. Results indicate that the use of regulatory databases is a promising way to enhance identification rates as well as to identify new, potentially hazardous compounds

Design and Implementation of Content Management System with Personalization

Import 02/11/2016Tato práce se zabývá navržením a částečnou implementací redakčního systému na výukový webový portál. Cílem práce je vytvořit funkční strukturu celého webového portálu včetně implementace možnosti personalizace a gamifikace. Teoretická část se zabývá východisky nasazení redakčních systémů a analýzou konkurence v oblasti online vzdělávání. V teoretické části jsou zmíněny hlavní pojmy z této oblasti jako Web 2.0, personalizace, responzivní design a rozděleny redakční systémy jako takové. V praktické části je poté samotné řešení návrhu, kde byly využity metodiky zmíněné v teoretické části, včetně ukázek veškerých kroků tvorby webového portálu.The bachelor's thesis is amited to the design and partial implementation of CMS to educational web portal. The aim is to create a functional structure of the entire website, including the implementation of personalization options and Gamification. The theoretical part is focused on the bases deployment of content management systems and analysis of competition in the field of online education. In the theoretical part is also described the main concepts of this field, like Web 2.0, personalization, responsive design and distributed content management systems as such. In the practical part is the actual design solutions, which were used methodology mentioned in the theoretical part, including examples of all the steps of creating a web portal.155 - Katedra aplikované informatikyvýborn

Experimental Trauma Models: An Update

Treatment of polytrauma patients remains a medical as well as socioeconomic challenge. Although diagnostics and therapy improved during the last decades, multiple injuries are still the major cause of fatalities in patients below 45 years of age. Organ dysfunction and organ failure are major complications in patients with major injuries and contribute to mortality during the clinical course. Profound understanding of the systemic pathophysiological response is crucial for innovative therapeutic approaches. Therefore, experimental studies in various animal models are necessary. This review is aimed at providing detailed information of common trauma models in small as well as in large animals