Penicilliform anthropomorphic manipulator

In the article a description of robot-equippe

Quantum analogue of the spin-flop transition for a spin pair

Quantum (step-like) magnetization curves are studies for a spin pair with antiferromagnetic coupling in the presence of a magnetic field parallel to the easy axis of the magnetic anisotropy. The consideration is done both analytically and numerically for a wide range of the anisotropy constants and spins up to $S \gtrsim 100$. Depending on the origin of the anisotropy (exchange or single-ion), the magnetization curve can demonstrate the jumps more than unity and the concentration of the unit jumps in a narrow range of the field. We also point the region of the problem parameters, where the behavior is quasiclassical for $S = 5$, and where system is substantially quantum in the limit $S \to \infty$.Comment: 5 pages, 5 figure

FEASIBILITY OF TYPE OF DEEP-WATER TECHNOLOGIES FOR THE EXTRACTION OF MARINE FERRO-MANGANESE NODULES

The conditions for the occurrence of near bottom minerals presented in the form of sulphides (the Logachev deposit) and ferro-manganese nodules (The conditions for the occurrence of benthic minerals presented in the form of sulphides (the Logachev deposit) and ferro-manganese nodules (FMN) are considered. An analysis of the structures and parameters of various means of collecting and transporting sulphides and iron ore from the bottom to the surface is given, and the possibility of effectively using vessel lifting on a cable-rope is indicated. Structural schemes for collecting FMN and sulphides in the form of containers on a cable, equipped with manipulators with gripping devices of a disc, drum or clamshell type, are proposed. In them, the capture of rock pieces or FMN is carried out by creating a vacuum in the collectors of the executive bodies and attracting to them pieces of rock or FMN by a pressure drop of water inside and outside the reservoir. It was given the approximate parameters of the mining system. So, for a cable-rope made of kevlar with a diameter of 50 mm, the capacity can be 200-400 thousand tons per year for one installation with different specific mass concentration of FMN per 1 m2) are considered

Highly Pertinent Algorithm for the Market of Business Intelligence, Context and Native Advertising

This article presents the study results of the business intelligence markets, the promote products on social media, and a new method for increasing the information pertinence in the scientific recommender systems, scientific information systems, analysis of the recommender systems that contain information about scientific publications, is represented. The prospects of using this method in the Business Intelligence systems, content management systems for native advertising systems to find content on the Internet and assessed the current state of the market such systems. Keywords: context and native advertising market, Business Intelligence market, highly pertinent algorithms, recommender systems JEL Classifications: A11, M30, M3

Direct laser writing of μ-chips based on hybrid C–Au–Ag nanoparticles for express analysis of hazardous and biological substances

Micro-chips based on organic–inorganic hybrid nanoparticles (NPs) composed of nanoalloys of gold (Au) and silver (Ag) embedded in an amorphous carbonaceous matrix (C–Au–Ag NPs) were prepared directly on a substrate by the laser- induced deposition (for short: LID) method. The C–Au–Ag NPs show a unique plasmon resonance which enhances Raman scattering of analytes, making the μ-chips suitable to detect ultra-low-volumes (10−12 liter) and concentrations (10−9 M) of bio-agents and a hazardous compound. These micro-chips constitute a novel, flexible solid-state device that can be used for applications in point-of-care diagnostics, consumer electronics, homeland security and environmental monitoring

Research Leadership of the “Priority 2030” Program: Success Factors

The article presents the results of comparative analysis of universities’ activities over the past five years, which won the special grant in the “Research Leadership” track of the “Priority 2030” program. The comparison is carried out between the following groups of universities: 1) all universities of the “Research Leadership” track, 2) the first, second and third groups, selected according to the results of the competition, and 3) group of Project 5-100 participants. The state strategic initiatives in the field of the higher education system over the past 15 years were considered to determine their impact on the development of the considered groups of universities; the indicators that make significant contribution to the results of educational, research, international and financial activities of universities were selected. The aggregation of indicators for university groups has been carried out using the Displaced Ideal method and the comparative analysis for 2016 – 2020. The significant indicators of scientific and research activities of analyzed groups of universities for 2018 – 2020 were considered. Based on the analysis, the most significant factors of success have been identified that ensured the victory of the considered universities in the Priority 2030 competition on the “Research Leadership” track

Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε

IKKε and TBK1 are noncanonical IKK family members which regulate inflammatory signaling pathways and also play important roles in oncogenesis. However, few inhibitors of these kinases have been identified. While the substrate specificity of IKKε has recently been described, the substrate specificity of TBK1 is unknown, hindering the development of high-throughput screening technologies for inhibitor identification. Here, we describe the optimal substrate phosphorylation motif for TBK1, and show that it is identical to the phosphorylation motif previously described for IKKε. This information enabled the design of an optimal TBK1/IKKε substrate peptide amenable to high-throughput screening and we assayed a 6,006 compound library that included 4,727 kinase-focused compounds to discover in vitro inhibitors of TBK1 and IKKε. 227 compounds in this library inhibited TBK1 at a concentration of 10 µM, while 57 compounds inhibited IKKε. Together, these data describe a new high-throughput screening assay which will facilitate the discovery of small molecule TBK1/IKKε inhibitors possessing therapeutic potential for both inflammatory diseases and cancer

The First Year of the Priority 2030 Program Implementation: Positive Results and Problem Areas of Research Track Universities

The article considers the results of the main activities of universities – participants’ groups of the Priority 2030 program of the «Leadership in Research» track (hereinafter referred to as the research track) at the initial stage of its implementation. An analysis of performance indicators’ dynamics for groups of universities in the period preceding the implementation of the program (2017–2020) and the first year of its implementation (2021) was carried out. Special attention is given to the analysis of the activities of universities that are leaders in the research track. As part of the comprehensive analysis, positive results were identified, as well as some problem areas in the activities of universities. An analysis of the basic indicators shows that the researched groups of universities in a number of indicators have a relatively small difference in the achieved values, while the indicators of the special part revealed an unconditional group of leaders