Avaliação do potencial farmacológico de chá de ayahuasca no manejo da ansiedade e depressão

Introduction: The vicissitudes of modern life, social, economic and behavioral instabilities have caused the consumption of teas, medicines, drugs and alcohol to increase as an alternative to escape from dayto-day problems. In recent years, some studies have shown the anxiolytic and antidepressant potential of Ayahuasca tea, based on reports by adherents of religious sects who seek a meaning for life or answers to their personal problems.Objective: The present study aims to analyze, in the light of a scientific context, the pharmacological potential of plants (Ayahuasca tea) in the treatment of depression, anxiety and panic syndrome.Material and methods: A bibliographic review was carried out in the electronic databases LILACS, SciELO, BDENF and CAPES between 1990 and 2019.Results: The analysis of the results shows that tea has anxiolytic and antidepressant potential due to the presence of tricyclic and beta-carbonyl compounds whose standardization in pharmaceutical forms may present alternatives for the management of anxiety and depression.Conclusions: Despite the anxiolytic and antidepressant potential, its use in the form of crude infusion is discouraged due to the lack of dose standardization, its hallucinogenic and toxicological potential.Introdução: As vicissitudes da vida moderna, as instabilidades sociais, econômicas e comportamentais tem feito com que o consumo de chás, medicamentos, drogas e álcool tenha aumentado como alternativa de fuga dos problemas do dia-a-dia. Nos últimos anos, alguns estudos mostraram um potencial ansiolítico e antidepressivo do chá de Ayahuasca, baseado em relatos de adeptos de seitas religiosas que buscam um sentido para a vida ou respostas para seus problemas pessoais.Objetivo: O presente estudo tem como objetivo analisar à luz de um contexto científico, o potencial farmacológico de plantas (chá Ayahuasca) no tratamento da depressão, ansiedade e síndrome do pânicoMateriais e métodos: Procedeu-se uma revisão bibliográfica nas base de dados eletrônicas LILACS, SciELO, BDENF e CAPES entre 1990 e 2019.Resultados: A análise dos resultados mostra que o chá apresenta potencial ansiolítico e antidepressivo pela presença de compostos tricíclicos e beta-carbonilas cuja padronização em formas farmacêuticas pode apresentar alternativas para o manejo da ansiedade e depressão.Conclusões: Apesar do potencial ansiolítico e antidepressivo, desestimula-se seu uso na forma de infusão bruta em razão da falta de padronização de dose, seu potencial alucinógeno e toxicológico

Central nervous system high-grade neuroepithelial tumor with BCOR alteration: case report

Central nervous system high-grade neuroepithelial tumors with BCOR alteration are a rare disease. Currently, there are only 24 cases reported in the literature. They are characterized by a change involving the BCOR gene and have a poor prognosis. Studies are needed to improve the current therapy and outcomes of these neoplasms. This case report describes the clinical history of a patient with this pathology and aims to contribute to the current knowledge about this new entity

Síndrome de Munchausen by proxy: definición, contextualización y factores psíquicos involucrados

The Munchausen syndrome by proxy refers to a pathology characterized by physical and emotional abuse in which the simulation or production of symptoms is directed towards a child, which involves taking him or her to health treatments and unnecessary surgeries. The difficulties in the diagnosis of this form of abuse and the emotional aspects involved highlight the destructive effects in the infancy subjectivity due to the lack of loving capacity protecting and prioritizing the child demands. Psychoanalysis offers a differentiated view, comprehending that the mother attempts to elaborate her own psychic conflicts by the repetition of traumatic experience. There is a necessity of comprehension of the instinct destructivity presented in the maternal unconscious dynamics revealed in the modality of caring which is reflected in violenceEl Síndrome de Munchausen by proxy se refiere a una patología caracterizada por el abuso físico o emocional, en donde la simulación o producción de síntomas es direccionada al hijo, llevando a tratamientos de salud y cirugías innecesarios. Las dificultades diagnósticas de este tipo de abuso y los aspectos emocionales implicados llaman atención por los efectos destructivos en la subjetividad infantil, fruto de una falla en la capacidad de amar, proteger y priorizar las demandas del hijo. El Psicoanálisis ofrece una mirada que retrata un intento de elaboración de los propios conflictos psíquicos por la vía de la repetición de vivencias traumáticas. Así, se percibe la necesidad de una comprensión de la destrucción pulsional presente en la dinámica inconsciente materna revelada por esta modalidad de cuidado que se traduce en violenci

Síndrome de Munchausen by proxy: definición, contextualización y factores psíquicos involucrados

El Síndrome de Munchausen by proxy se refiere a una patología caracterizada por el abuso físico o emocional, en donde la simulación o producción de síntomas es direccionada al hijo, llevando a tratamientos de salud y cirugías innecesarios. Las dificultades diagnósticas de este tipo de abuso y los aspectos emocionales implicados llaman atención por los efectos destructivos en la subjetividad infantil, fruto de una falla en la capacidad de amar, proteger y priorizar las demandas del hijo. El Psicoanálisis ofrece una mirada que retrata un intento de elaboración de los propios conflictos psíquicos por la vía de la repetición de vivencias traumáticas. Así, se percibe la necesidad de una comprensión de la destrucción pulsional presente en la dinámica inconsciente materna revelada por esta modalidad de cuidado que se traduce en violencia

Síndrome de Munchausen by proxy: definición, contextualización y factores psíquicos involucrados

The Munchausen syndrome by proxy refers to a pathology characterized by physical and emotional abuse in which the simulation or production of symptoms is directed towards a child, which involves taking him or her to health treatments and unnecessary surgeries. The difficulties in the diagnosis of this form of abuse and the emotional aspects involved highlight the destructive effects in the infancy subjectivity due to the lack of loving capacity protecting and prioritizing the child demands. Psychoanalysis offers a differentiated view, comprehending that the mother attempts to elaborate her own psychic conflicts by the repetition of traumatic experience. There is a necessity of comprehension of the instinct destructivity presented in the maternal unconscious dynamics revealed in the modality of caring which is reflected in violence.El Síndrome de Munchausen by proxy se refiere a una patología caracterizada por el abuso físico o emocional, en donde la simulación o producción de síntomas es direccionada al hijo, llevando a tratamientos de salud y cirugías innecesarios. Las dificultades diagnósticas de este tipo de abuso y los aspectos emocionales implicados llaman atención por los efectos destructivos en la subjetividad infantil, fruto de una falla en la capacidad de amar, proteger y priorizar las demandas del hijo. El Psicoanálisis ofrece una mirada que retrata un intento de elaboración de los propios conflictos psíquicos por la vía de la repetición de vivencias traumáticas. Así, se percibe la necesidad de una comprensión de la destrucción pulsional presente en la dinámica inconsciente materna revelada por esta modalidad de cuidado que se traduce en violencia

Central nervous system high-grade neuroepithelial tumor with BCOR alteration: case report

Central nervous system high-grade neuroepithelial tumors with BCOR alteration are a rare disease. Currently, there are only 24 cases reported in the literature. They are characterized by a change involving the BCOR gene and have a poor prognosis. Studies are needed to improve the current therapy and outcomes of these neoplasms. This case report describes the clinical history of a patient with this pathology and aims to contribute to the current knowledge about this new entity