Coulomb blockade in one-dimensional arrays of high conductance tunnel junctions

Properties of one-dimensional (1D) arrays of low Ohmic tunnel junctions (i.e. junctions with resistances comparable to, or less than, the quantum resistance $R_{\rm q}\equiv h/e^2\approx 25.8$ k$\Omega$) have been studied experimentally and theoretically. Our experimental data demonstrate that -- in agreement with previous results on single- and double-junction systems -- Coulomb blockade effects survive even in the strong tunneling regime and are still clearly visible for junction resistances as low as 1 k$\Omega$. We have developed a quasiclassical theory of electron transport in junction arrays in the strong tunneling regime. Good agreement between the predictions of this theory and the experimental data has been observed. We also show that, due to both heating effects and a relatively large correction to the linear relation between the half-width of the conductance dip around zero bias voltage, $V_{1/2}$, and the measured electronic temperature, such arrays are inferior to those conventionally used in the Coulomb Blockade Thermometry (CBT). Still, the desired correction to the half-width, $\Delta V_{1/2}$, can be determined rather easily and it is proportional to the magnitude of the conductance dip around zero bias voltage, $\Delta G$. The constant of proportionality is a function of the ratio of the junction and quantum resistances, $R/R_{\rm q}$, and it is a pure strong tunneling effect.Comment: LaTeX file + five postscript figure

Rationality as the Rule of Reason

The demands of rationality are linked both to our subjective normative perspective (given that rationality is a person-level concept) and to objective reasons or favoring relations (given that rationality is non-contingently authoritative for us). In this paper, I propose a new way of reconciling the tension between these two aspects: roughly, what rationality requires of us is having the attitudes that correspond to our take on reasons in the light of our evidence, but only if it is competent. I show how this view can account for structural rationality on the assumption that intentions and beliefs as such involve competent perceptions of downstream reasons, and explore various implications of the account

One nutritional symbiosis begat another : Phylogenetic evidence that the ant tribe Camponotini acquired Blochmannia by tending sap-feeding insects

© 2009 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License. The definitive version was published in BMC Evolutionary Biology 9 (2009): 292, doi:10.1186/1471-2148-9-292.Bacterial endosymbiosis has a recurring significance in the evolution of insects. An estimated 10-20% of insect species depend on bacterial associates for their nutrition and reproductive viability. Members of the ant tribe Camponotini, the focus of this study, possess a stable, intracellular bacterial mutualist. The bacterium, Blochmannia, was first discovered in Camponotus and has since been documented in a distinct subgenus of Camponotus, Colobopsis, and in the related genus Polyrhachis. However, the distribution of Blochmannia throughout the Camponotini remains in question. Documenting the true host range of this bacterial mutualist is an important first step toward understanding the various ecological contexts in which it has evolved, and toward identifying its closest bacterial relatives. In this study, we performed a molecular screen, based on PCR amplification of 16S rDNA, to identify bacterial associates of diverse Camponotini species. Phylogenetic analyses of 16S rDNA gave four important insights: (i) Blochmannia occurs in a broad range of Camponotini genera including Calomyrmex, Echinopla, and Opisthopsis, and did not occur in outgroups related to this tribe (e.g., Notostigma). This suggests that the mutualism originated in the ancestor of the tribe Camponotini. (ii) The known bacteriocyte-associated symbionts of ants, in Formica, Plagiolepis, and the Camponotini, arose independently. (iii) Blochmannia is nestled within a diverse clade of endosymbionts of sap-feeding hemipteran insects, such as mealybugs, aphids, and psyllids. In our analyses, a group of secondary symbionts of mealybugs are the closest relatives of Blochmannia. (iv) Blochmannia has cospeciated with its known hosts, although deep divergences at the genus level remain uncertain. The Blochmannia mutualism occurs in Calomyrmex, Echinopla, and Opisthopsis, in addition to Camponotus, and probably originated in the ancestral lineage leading to the Camponotini. This significant expansion of its known host range implies that the mutualism is more ancient and ecologically diverse than previously documented. Blochmannia is most closely related to endosymbionts of sap-feeding hemipterans, which ants tend for their carbohydrate-rich honeydew. Based on phylogenetic results, we propose Camponotini might have originally acquired this bacterial mutualist through a nutritional symbiosis with other insects.Funding for this research was provided by grants from the NSF (MCB-0604177) and NIH (R01GM062626) to JJW, and from the NSF-supported Ant AToL project (EF-0431330) to PSW and SGB

Quantum Conductance of the Single Electron Transistor

The quantum conductance of the single-electron tunneling (SET) transistor is investigated in this paper by the functional integral approach. The formalism is valid for arbitrary tunnel resistance of the junctions forming the SET transistor at any temperature. The path integrals are evaluated by the semiclassical method to yield an explicit non-perturbation form of the quantum conductance of the SET transistor. An anomaly of the quantum conductance is found if the tunnel resistances are much smaller than the quantum resistance. The dependence of the conductance on the gate voltage is also discussed.Comment: 4 pages including some mathe details of cond-mat/990806

Effect of quantum noise on Coulomb blockade in normal tunnel junctions at high voltages

We have investigated asymptotic behavior of normal tunnel junctions at voltages where even the best ohmic environments start to look like RC transmission lines. In the experiments, this is manifested by an exceedingly slow approach to the linear behavior above the Coulomb gap. As expected on the basis of the quantum theory taking into account interaction with the environmental modes, better fits are obtained using 1/sqrt{V}- than 1/V- dependence for the asymptote. These results agree with the horizon picture if the frequency-dependent phase velocity is employed instead of the speed of light in order to determine the extent of the surroundings seen by the junction.Comment: 9 pages, 4 figures, submitted to Phys. Rev.

Increase in outbreaks of gastroenteritis linked to bathing water in Finland in summer 2014

Peer reviewe

Statistics of Heat Transfer in Mesoscopic Circuits

A method to calculate the statistics of energy exchange between quantum systems is presented. The generating function of this statistics is expressed through a Keldysh path integral. The method is first applied to the problem of heat dissipation from a biased mesoscopic conductor into the adjacent reservoirs. We then consider energy dissipation in an electrical circuit around a mesoscopic conductor. We derive the conditions under which measurements of the fluctuations of heat dissipation can be used to investigate higher order cumulants of the charge counting statistics of a mesoscopic conductor.Comment: 9 pages, 6 figure

Совершенствование региональных целевых программ – инструмента управления социально-экономическим развитием Одесского региона и его конкурентоспособностью

Розглянуто регіональні цільові програми розвитку Одеського регіону; виявлено недоліки діючого підходу до розробки й оцінки програм на регіональному рівні; подано рекомендації щодо загальних підходів до програмного управління, експертизи проектів; запропоновано експертний метод оцінки ефективності цільових програм із точки зору управління процесом розробки та реалізацією програм, своєчасного прийняття рішень. Ключові слова: регіональні цільові програми, соціально-економічний розвиток, регіон, управління, конкурентоспроможність.Рассмотрены региональные целевые программы развития Одесского региона; выявлены недостатки действующего подхода к разработке и оценке программ на региональном уровне; даны рекомендации по общим подходам к программному управлению, экспертизе проектов; предложен экспертный метод оценки эффективности целевых программ с точки зрения управления процессом разработки и ходом реализации программ, своевременного принятия решений. Ключевые слова: региональные целевые программы, социально-экономическое развитие, регион, управление, конкурентоспособность.The paper considers the regional target programs of Odessa region development. Shortcomings of the present approach to the development and evaluation of programs at the regional level are shown, recommendations on common approaches to program management and project appraisal are given; expert method for evaluating target programs is proposed from the view of managing the process of development and implementation of programs, timely decisions. Keywords: regional target programs, socio-economic development, region, management, competitiveness

Determining collagen distribution in articular cartilage using contrast-enhanced micro-computed tomography

Objective: Collagen distribution within articular cartilage (AC) is typically evaluated from histological sections, e.g., using collagen staining and light microscopy (LM). Unfortunately, all techniques based on histological sections are time-consuming, destructive, and without extraordinary effort, limited to two dimensions. This study investigates whether phosphotungstic acid (PTA) and phosphomolybdic acid (PMA), two collagen-specific markers and X-ray absorbers, could (1) produce contrast for AC X-ray imaging or (2) be used to detect collagen distribution within AC. Method: We labeled equine AC samples with PTA or PMA and imaged them with micro-computed tomography (micro-CT) at pre-defined time points 0, 18, 36, 54, 72, 90, 180, 270 h during staining. The micro-CT image intensity was compared with collagen distributions obtained with a reference technique, i.e., Fourier-transform infrared imaging (FTIRI). The labeling time and contrast agent producing highest association (Pearson correlation, BlandeAltman analysis) between FTIRI collagen distribution and micro-CT -determined PTA distribution was selected for human AC. Results: Both, PTA and PMA labeling permitted visualization of AC features using micro-CT in non-calcified cartilage. After labeling the samples for 36 h in PTA, the spatial distribution of X-ray attenuation correlated highly with the collagen distribution determined by FTIRI in both equine (mean +/- S.D. of the Pearson correlation coefficients, r = 0.96 +/- 0.03, n = 12) and human AC (r = 0.82 +/- 0.15, n = 4). Conclusions: PTA-induced X-ray attenuation is a potential marker for non-destructive detection of AC collagen distributions in 3D. This approach opens new possibilities in development of non-destructive 3D histopathological techniques for characterization of OA. (C) 2015 The Authors. Published by Elsevier Ltd and Osteoarthritis Research Society International.Peer reviewe