Innovation in vocational education of persons with disabilities

The article discusses the training of persons with disabilities in the different layers of educationВ статье рассматривается профессиональное обучение инвалидов в разных слоях образовани

A Fuzzy Approach to the Synthesis of Cognitive Maps for Modeling Decision Making in Complex Systems

The object of this study is fuzzy cognitive modeling as a means of studying semistructured socio-economic systems. The features of constructing cognitive maps, providing the ability to choose management decisions in complex semistructured socio-economic systems, are described. It is shown that further improvement of technologies necessary for developing decision support systems and their practical use is still relevant. This work aimed to improve the accuracy of cognitive modeling of semistructured systems based on a fuzzy cognitive map of structuring nonformalized situations (MSNS) with the evaluation of root-mean-square error (RMSE) and mean average squared error (MASE) coefficients. In order to achieve the goal, the following main methods were used: systems analysis methods, fuzzy logic and fuzzy sets theory postulates, theory of integral wavelet transform, correlation and autocorrelation analyses. As a result, a new methodology for constructing MSNS was proposed—a map of structuring nonformalized situations that combines the positive properties of previous fuzzy cognitive maps. The solution of modeling problems based on this methodology should increase the reliability and quality of analysis and modeling of semistructured systems and processes under uncertainty. The analysis using open datasets proved that compared to the classical ARIMA, SVR, MLP, and Fuzzy time series models, our proposed model provides better performance in terms of MASE and RMSE metrics, which confirms its advantage. Thus, it is advisable to use our proposed algorithm in the future as a mathematical basis for developing software tools for the analysis and modeling of problems in semistructured systems and processes. Doi: 10.28991/ESJ-2022-06-02-012 Full Text: PD

Економічна ефективність використання корів-первісток голштинської породи з різною інтенсивністю їх формування у ранньому оногенезі

The increase in milk productivity is indissolubly related to the production economy, as the payment of food for dairy products is directly dependent on the volume of the dairy. The aim of the research was to establish the economic efficiency of using the first-born cows of Holstein breed with different intensity of their formation in early ontogenesis. Experimental heifers significantly differed in development, both at the beginning and at the end of their breed. By the size of the live weight, the heifers and the experimental group dominated the elders with a high degree of confidence in the difference. At 6 months of age, the difference was 16.90 kg (10.40%), 12 months – 19.85 kg (7.07%) and 18 months – 21.75 kg (5.79%). Absolute gain for the period 0–6 months  in the first group was 17.15 kg more than in the second and was 153.75 kg. In the periods of 6–12 and 12–18 months, no reliable difference was found for this indicator. The analysis of average daily gains of experimental animals showed that the heifers of the first group for this indicator faithfully prevailed in the age groups of 0–6 and 0–18 months, respectively: 95.3 g (12.6%) and 40.7 g (6,4%). Average daily gains at the age of 6–12 and 12–18 months  in the heifers of groups I and II did not significally differ. The analysis of the milk productivity of the first-breed cows at different intensities of formation showed that the first-breed cows, which had higher daily average gains, were significantly superior to those of the same age with a lower intensity of formation of 1093.0 kg (28.06% for P > 0.999). The fat content of milk in experimental animals was not significantly different. Animals of the first group were characterized by high milk productivity.  Their milk yield for the fitst lactation amounted to 4988.5 kg, up to the second lactation it increased by 222.1 kg (4.5%), from the second to the third lactation by 304.0 kg (5.8%), and in general from the first to the third – by 526.1 kg (10.5%).  The milk productivity the first-breed cows of the second group was 3895.5 kg, the increase in the supply of the second lactation amounted to 906.3 kg (23.3%), productivity growth from from the second to the third lactation was 376.7 kg (7.8%), in the period from the first to the third lactation in this group, the overall increase in fertility increased by 1283.0 kg (32.9%). The rate of formation of primary cows in early ontogenesis of cows more affects the pulse rate and rectal body temperature and is less in the frequency of respiratory movements. In the first-born cows with a fast intensity of formation compared with analogues with a slow intensity of formation, a tendency towards higher rates of pulse and respiratory movements at a lower rectal body temperature have been observed. During conducting the correlation analysis of the relationship between the live weight at different ages of the first-born cows and the content of fat in milk we have been revealed a positive average power of a reliable relationship between live weight at the age of 6 and 18 months with the tardiness of the first lactation.  The relationship between live weight and fat content in milk was weak and unreliable. From the the first-born cows with a rapid intensity of formation, in comparison with the first-borns with a slow intensity of formation, more milk was extracted at a cost of 9890.6 UAH.  (on 100 heads – 989060,0). Calculated indicators of economic efficiency prove the expediency of selecting cows, not only on the indicators of dairy productivity, but also on such indicator as the intensity of the formation of the heifers up to 18 months of age.  In this case, it is necessary to take into account the average daily increment of live weight of heifers, which in the future can ensure the maximum profit of the milk industry.Підвищення молочної продуктивності нерозривно пов’язано з економікою виробництва, тому що оплата корму молочною продукцією перебуває в прямій залежності від величини надоїв. Метою досліджень було встановлення економічної ефективності використання корів-первісток голштинської породи з різною інтенсивністю їх формування у ранньому онтогенезі. Піддослідні телиці достовірно відрізнялися за розвитком  як на початку, так і в кінці вирощування. За величиною живої маси  телиці І піддослідної групи переважали ровесниць з високою достовірністю різниці. У 6-місячному віці різниця становила 16,90 кг (10,40%), 12-місячному – 19,85 кг (7,07%) та 18-місячному – 21,75 кг (5,79%). Корови-первістки, які мали вищі середньодобові прирости, достовірно переважали ровесниць з нижчою інтенсивністю формування за величиною надою на 1093,0 кг (28,06% за Р > 0,999). Вміст жиру в молоці піддослідних тварин суттєво не відрізнявся. У первісток зі швидкою інтенсивністю формування порівняно з аналогами з повільною інтенсивністю формування спостерігається тенденція до вищих показників частоти пульсу та дихальних рухів при меншій ректальній температурі тіла. Від корів-первісток зі швидкою інтенсивністю формування порівняно з первістками з повільною інтенсивністю формування отримали додатково більше молока вартістю 9890,6 грн. (на 100 голів – 989060,0)

Hematological indicators of the blood of males and females of the Ukrainian scaled carp breed

The research results on hematological indicators of males and females of the Ukrainian scaly breed of carp grown in the conditions of a fish farm in the Dnipropetrovsk region are given. In Ukraine, carp cultivation is becoming an increasingly popular method of commercial fish production. At the same time, the hydrochemical and temperature regimes of the reservoir have important practical significance for the average growth and development of fish since the intensity of respiration, metabolic processes, fish nutrition, motor activity, and resistance to various diseases depend on the chemical composition and temperature of the water. The process of formation of the hydrochemical composition of pond water occurs against the background of climatic changes. Therefore, control of temperature conditions and the physiological state of fish during carp cultivation is an important measure that ensures rational consumption of feed and high growth rates and, in the future, allows to plan of optimal cultivation technology. Therefore, the work aimed to investigate the hematological indicators of blood in males and females of the Ukrainian scaly breed of carp to control their physiological state in the conditions of the hydrochemical and temperature regime of the reservoir of the fish farm. It was established that the main hydrochemical parameters corresponded to the technological standards adopted in fish farming to cultivate carp fish. The hematological parameters of the blood of male and female carp were within the physiological norm. The determined blood composition is natural and characterizes changes in the body of fish according to the season, which reflects adaptation processes in the conditions of seasonal fluctuations in water temperature. Correlative relationships between carp blood's hematological parameters and their keeping temperature conditions were revealed. The pH of the medium (r = 0.28–0.34) has the most significant effect on hematological indicators of carp blood. A positive correlative relationship was established between water temperature and the level of hemoglobin, a color indicator, and the number of erythrocytes and leukocytes in the blood of fish, which was in the range of r = 0.21–0.26. There was a negative relationship between the water temperature indicator and the content of segmented nuclear neutrophils (r = 0.24). The variance analysis of the one-factor complex revealed a significant and most highly probable influence of the conditions of keeping carp on the hemoglobin content, the number of erythrocytes, leukocytes, and the color index of the carp's blood. The share of influence was from 56.14 to 76.90 %. The amplitude of water temperature is essential for favorable conditions for hydrophones and the formation of a natural feed base. In addition, the environment's temperature affects the speed of biological processes in fish. Therefore, the organization of carp feeding, considering scientifically based norms depending on the protein content in compound feed, water temperature, fish weight, and density of its landing, will contribute to ensuring high fish productivity and rational use of feed

Electron microscopy analysis of ATP-independent nucleosome unfolding by FACT

FACT is a histone chaperone that participates in nucleosome removal and reassembly during transcription and replication. We used electron microscopy to study FACT, FACT:Nhp6 and FACT:Nhp6:nucleosome complexes, and found that all complexes adopt broad ranges of configurations, indicating high flexibility. We found unexpectedly that the DNA binding protein Nhp6 also binds to the C-terminal tails of FACT subunits, inducing more open geometries of FACT even in the absence of nucleosomes. Nhp6 therefore supports nucleosome unfolding by altering both the structure of FACT and the properties of nucleosomes. Complexes formed with FACT, Nhp6, and nucleosomes also produced a broad range of structures, revealing a large number of potential intermediates along a proposed unfolding pathway. The data suggest that Nhp6 has multiple roles before and during nucleosome unfolding by FACT, and that the process proceeds through a series of energetically similar intermediate structures, ultimately leading to an extensively unfolded form

Assessment of visceral adipose tissue in patients with coronary artery disease using bioelectrical impedance analysis

Aim. To study visceral adipose tissue (VAT) content in patients with coronary artery disease (CAD) using the bioimpedance analysis, to identify metabolic disorders associated with visceral obesity, and to determine the role of individual risk factors in the formation of coronary artery lesions using modern statistical methods.Material and methods. A total of 152 patients were examined (women, 66; men, 86). The median age of patients was 63 [55;69] years. This observational study assessed anthropometric parameters, such as height, weight, body mass index, waist circumference, whole-body fat percentage, and specifically VAT mass, as well as the relationship of these parameters with blood levels of triglycerides, high-density lipoprotein cholesterol (HDL-C) and glucose. Height was measured using a metal height meter RM-1 “Diakoms”. Weight, body mass index, wholebody fat percentage, and VAT mass were measured using the Omron BF-508 body composition monitor (Omron, Japan). Epicardial adipose tissue (EAT) thickness was assessed using two-dimensional echocardiography on a Philips Sonos 5500 ultrasound system (Germany).Results. Bioimpedance analysis revealed a higher VAT content in patients with CAD compared with those without CAD (14 [11;18]% vs 13 [10;14,5]%, respectively (p=0,025)). During the ROC analysis, cut-off values for VAT ≥15% and EAT ≥7,5 mm were identified, associated with a higher risk of CAD. In multivariate analysis, only HDL-C levels were significantly associated with CAD, while at the same time, univariate analysis demonstrated the significance of VAT and EAT in predicting CAD.Conclusion. The results showed that an increased VAT content and low HDL-C level is associated with the presence of CAD

Properties of ZnO/ZnAl2_2O4_4 composite PEO coatings on zinc

Recently the successful formation of PEO coatings on zinc in a phosphate aluminate electrolyte was shown. The produced composite coatings contain various mixtures of ZnO and ZnAl$_2$O$_4$. In frame of the current study, the properties of the formed coatings including adhesion/cohesion, wear, corrosion and photocatalytic activity were analysed to identify possible applications. However, the coatings show internal porosity and a sponge-like structure. Thus the cohesion within the coating is quite low. Pull-off tests have demonstrated clear rupture within the PEO layer at strength values as low as 1 MPa. The photocatalytic activity is limited, in spite of the formation of a higher amount of ZnO at shorter treatment times. Interestingly, the composite coatings of ZnO and higher amounts of ZnAl$_2$O$_4$ spinel showed a higher activity, but not sufficient for fast and effective catalytic cleaning applications

Циклодиализ в лечении глаукомы. История и современность

Cyclodialysis was proposed in 1905 by Leopold Heine and actively criticized by his contemporaries, but later received a worldwide recognition in the field of open-angle and aphakic glaucoma surgery. A number of modifications has been proposed, including the combination with other hypotensive surgeries as well as the implantation of various drainage systems, fabrics and materials into the cyclodialys cleft. The effect of this surgical procedure can be attributed to the increase in uveoscleral outflow and the reduction of intraocular fluid production. Currently, cyclodialysis gave way to laser trabeculoplasty and trabeculectomy. However, cyclodialysis modifications are still used in surgical treatment of refractory glaucoma in combination with other surgeries, including cataract extraction.Циклодиализ, предложенный в 1905 г. Леопольдом Гейне и активно критикуемый его современниками, впоследствии получил мировое признание, главным образом, в хирургии открытоугольной и афакичной глаукомы. Было предложено много модификаций, в том числе сочетание циклодиализа с другими гипотензивными операциями, а также имплантации различных тканей и материалов в циклодиализную щель. Эффект вмешательства объясняется увеличением увеосклерального оттока и снижением продукции внутриглазной жидкости. В настоящее время циклодиализ уступил место лазерной трабекулопластике и трабекулэктомии. Тем не менее модификации циклодиализа применяются в хирургии рефрактерных форм глаукомы и в комбинации с другими вмешательствами, включая экстракцию катаракты