Comment on "Liquid-Liquid Phase Transition in Supercooled Yttria-Alumina"

A Comment on the Letter by Adrian C. Barnes et al., Phys. Rev. Lett. 103 225702 (2009). The authors of the Letter offer a Reply

PGC - 1α Overexpression Improves Angiogenic Signaling Potential of Skeletal Muscle - derived Extracellular Vesicles

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Computer modelling of a penetrator thermal sensor

The Philae lander is part of the Rosetta mission to investigate comet 67P/Churyumov-Gerasimenko. It will use a harpoon like device to anchor itself onto the surface. The anchor will perhaps reach depths of 1–2 m. In the anchor is a temperature sensor that will measure the boundary temperature as part of the MUPUS experiment. As the anchor attains thermal equilibrium with the comet ice it may be possible to extract the thermal properties of the surrounding ice, such as the thermal diffusivity, by using the temperature sensor data. The anchor is not an optimal shape for a thermal probe and application of analytical solutions to the heat equation is inappropriate. We prepare a numerical model to fit temperature sensor data and extract the thermal diffusivity. Penetrator probes mechanically compact the material immediately surrounding them as they enter the target. If the thermal properties, composition and dimensions of the penetrator are known, then the thermal properties of this pristine material may be recovered although this will be a challenging measurement. We report on investigations, using a numerical thermal model, to simulate a variety of scenarios that the anchor may encounter and how they will affect the measurement

An ultraviolet simulator for the incident Martian surface radiation and its applications

Ultraviolet (UV) radiation can act on putative organic/biological matter at the Martian surface in several ways. Only absorbed, but not transmitted or reflected, radiation energy can be photo-chemically effective. The most important biological UV effects are due to photochemical reactions in nucleic acids, DNA or RNA, which constitute the genetic material of all cellular organisms and viruses. Protein or lipid effects generally play a minor role, but they are also relevant in some cases. UV radiation can induce wavelengths-specific types of DNA damage. At the same time it can also induce the photo-reversion reaction of a UV induced DNA photoproduct of nucleic acid bases, the pyrimidine dimers. Intense UVB and UVC radiation, experienced on early Earth and present-day Mars, has been revealed to be harmful to all organisms, including extremophile bacteria and spores. Moreover, the formation of oxidants, catalytically produced in the Martian environment through UV irradiation, may be responsible for the destruction of organic matter on Mars. Following this, more laboratory simulations are vital in order to investigate and understand UV effects on organic matter in the case of Mars. We have designed a radiation apparatus that simulates the anticipated Martian UV surface spectrum between 200 and 400 nm (UVC-UVA). The system comprises a UV enhanced xenon arc lamp, special filter-sets and mirrors to simulate the effects of the Martian atmospheric column and dust loading. We describe the technical setup and performance of the system and discuss its uses for different applications. The design is focused on portability, therefore, the Mars-UV simulator represents a device for several different Mars simulation facilities with specific emphasis on Mars research topics

Detection of first-order liquid/liquid phase transitions in yttrium oxide-aluminium oxide melts

We combine small-angle x-ray scattering (SAXS) and wide-angle x-ray scattering (WAXS) with aerodynamic levitation techniques to study in situ phase transitions in the liquid state under contactless conditions. At very high temperatures, yttria-alumina melts show a first-order transition, previously inferred from phase separation in quenched glasses. We show how the transition coincides with a narrow and reversible maximum in SAXS indicative of liquid unmixing on the nanoscale, combined with an abrupt realignment in WAXS features related to reversible shifts in polyhedral packing on the atomic scale. We also observed a rotary action in the suspended supercooled drop driven by repetitive transitions (a polyamorphic rotor) from which the reversible changes in molar volume (1.2 ± 0.2 cubic centimeters) and entropy (19 ± 4 joules mole–1 kelvin–1) can be estimated

New insights in dermatophyte research

Dermatophyte research has renewed interest because of changing human floras with changing socioeconomic conditions, and because of severe chronic infections in patients with congenital immune disorders. Main taxonomic traits at the generic level have changed considerably, and now fine-tuning at the species level with state-of-the-art technology has become urgent. Research on virulence factors focuses on secreted proteases now has support in genome data. It is speculated that most protease families are used for degrading hard keratin during nitrogen recycling in the environment, while others, such as Sub6 may have emerged as a result of ancestral gene duplication, and are likely to have specific roles during infection. Virulence may differ between mating partners of the same species and concepts of zoo- and anthropophily may require revision in some recently redefined species. Many of these questions benefit from international cooperation and exchange of materials. The aim of the ISHAM Working Group Dermatophytes aims to stimulate and coordinate international networking on these fungi

Penetrometry of granular and moist planetary surface materials: Application to the Huygens landing site on Titan

The Huygens probe landed on the then unknown surface of Titan in January 2005. A small, protruding penetrometer, part of the Surface Science Package (SSP), was pushed into the surface material measuring the mechanical resistance of the ground as the probe impacted the landing site. We present laboratory penetrometry into room temperature surface analogue materials using a replica penetrometer to investigate further the nature of Titan's surface and examine the sensor's capabilities. The results are then compared to the flight instrument's signature and suggest the Titan surface substrate material consists of sand-sized particles with a mean grain size ~2 mm. A possible thin 7 mm coating with mechanical properties similar to terrestrial snow may overlie this substrate, although due to the limited data we are unable to detect any further layering or grading within the near-surface material. The unusual weakening with depth of the signature returned from Titan has, to date, only been reproduced using a damp sand target that becomes progressively wetter with depth, and supports the suggestion that the surface may consist of a damp and cohesive material with interstitial liquid contained between its grains. Comparison with terrestrial analogues highlights the unusual nature of the landing site material

People, context, and devices: Defining the new landscape of TV experiences

Modern technologies (e.g., tablet, smartphone, large public displays) remove many of the constraints that define the scope of what television is or can be, but we often define it based upon our prior TV experiences with broadcast and cable television. This one-day workshop at TVX 2015 will address design challenges and opportunities (e.g., of video streams, social TV apps, second screens) in order to consolidate existing knowledge to describe the changing landscape of TV experiences. It's time to redefine what we think of when we say "television," and this workshop will engage participants in that process