Implementation of a Microcode-controlled State Machine and Simulator in AVR Microcontrollers (MICoSS)

This paper describes the design of a microcode-controlled state machine and its software implementation in Atmel AVR microcontrollers. In particular, ATmega103 and ATmega128 microcontrollers are used. This design is closely related to the software implementation of a simulator in AVR microcontrollers. This simulator communicates with the designed state machine and presents a complete design environment for microcode development and debugging. These two devices can be interconnected by a flat cable and linked to a computer through a serial or USB interface.Both devices share the control software that allows us to create and edit microprograms and to control the whole state machine. It is possible to start, cancel or step through the execution of the microprograms. The operator can also observe the current state of the state machine. The second part of the control software enables the operator to create and compile simulating programs. The control software communicates with both devices using commands. All the results of this communication are well arranged in dialog boxes and windows.

An overview of generalized entropic forms

The aim of this focus letter is to present a comprehensive classification of the main entropic forms introduced in the last fifty years in the framework of statistical physics and information theory. Most of them can be grouped into three families, characterized by two-deformation parameters, introduced respectively by Sharma, Taneja, and Mittal (entropies of degree $(\alpha,\,\beta$)), by Sharma and Mittal (entropies of order $(\alpha,\,\beta)$), and by Hanel and Thurner (entropies of class $(c,\,d)$). Many entropic forms examined will be characterized systematically by means of important concepts such as their axiomatic foundations {\em \`{a} la} Shannon-Khinchin and the consequent composability rule for statistically independent systems. Other critical aspects related to the Lesche stability of information measures and their consistency with the Shore-Johnson axioms will be briefly discussed on a general ground.Comment: 14 pages, 6 tables, no figures, to appear on EPL: Focus Issues "Progresses on Statistical Physics and Complexity

Separation of lepidolite from hard-rock pegmatite ore via dry processing and flotation

ABSTRACT: A mineralogical study of Goncalo lithium-bearing mica-rich pegmatite ore (Portugal) indicated that lepidolite occurs in coarse-grained textures, which allows an appreciable liberation of gangue minerals (quartz, k-feldspar, and albite) from lepidolite. However, the intergrowth of these gangue minerals results in uncomplicated liberation (i.e., inclusions). Taking advantage of this coarse gangue liberation, optical ore sorting through image analysis was attempted in order to predict the grades of different-sized fractions using a random comminution algorithm. The ore-sorting process allowed the production of a marketable Li pre-concentrate product for metallurgy. Moreover, this method also highlighted the possible valuation of the reject as low-Li-content quartz-feldspar mixtures for the ceramic industry (reduction in the temperature of porosity closing). Furthermore, a scaled approach of grinding and sieving allowed the formation of a lepidolite-rich fraction (>210 mu m), which was processed using an electrostatic separator by varying key process parameters. The lepidolite and muscovite were separated to obtain a Li pre-concentrate assaying 3.5 % Li2O from a feed grade containing 1.8 % Li2O. Nevertheless, according to the zeta-potential measurements, the flotation test performed with the finer-sized fraction (-210 + 63 mu m) showed that lepidolite flotation was optimised between pH 3 and 5. In this pH range, concentrates from the rougher stage assayed 4.2-4.5 % Li2O, corresponding to 87-95 % Li recovery. At pH > 5, the selectivity decreases, and SiO2 analysis suggests the flotation of quartz and other silicates rather than lepidolite. Feldspar/quartz flotation was also tested using lepidolite flotation rejects to promote the separation of feldspars from quartz and obtain products for ceramic applications.info:eu-repo/semantics/publishedVersio

A probabilistic model for gene content evolution with duplication, loss, and horizontal transfer

We introduce a Markov model for the evolution of a gene family along a phylogeny. The model includes parameters for the rates of horizontal gene transfer, gene duplication, and gene loss, in addition to branch lengths in the phylogeny. The likelihood for the changes in the size of a gene family across different organisms can be calculated in O(N+hM^2) time and O(N+M^2) space, where N is the number of organisms, $h$ is the height of the phylogeny, and M is the sum of family sizes. We apply the model to the evolution of gene content in Preoteobacteria using the gene families in the COG (Clusters of Orthologous Groups) database

Extensive Copy-Number Variation of Young Genes across Stickleback Populations

MM received funding from the Max Planck innovation funds for this project. PGDF was supported by a Marie Curie European Reintegration Grant (proposal nr 270891). CE was supported by German Science Foundation grants (DFG, EI 841/4-1 and EI 841/6-1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Integrating Sequencing Technologies in Personal Genomics: Optimal Low Cost Reconstruction of Structural Variants

The goal of human genome re-sequencing is obtaining an accurate assembly of an individual's genome. Recently, there has been great excitement in the development of many technologies for this (e.g. medium and short read sequencing from companies such as 454 and SOLiD, and high-density oligo-arrays from Affymetrix and NimbelGen), with even more expected to appear. The costs and sensitivities of these technologies differ considerably from each other. As an important goal of personal genomics is to reduce the cost of re-sequencing to an affordable point, it is worthwhile to consider optimally integrating technologies. Here, we build a simulation toolbox that will help us optimally combine different technologies for genome re-sequencing, especially in reconstructing large structural variants (SVs). SV reconstruction is considered the most challenging step in human genome re-sequencing. (It is sometimes even harder than de novo assembly of small genomes because of the duplications and repetitive sequences in the human genome.) To this end, we formulate canonical problems that are representative of issues in reconstruction and are of small enough scale to be computationally tractable and simulatable. Using semi-realistic simulations, we show how we can combine different technologies to optimally solve the assembly at low cost. With mapability maps, our simulations efficiently handle the inhomogeneous repeat-containing structure of the human genome and the computational complexity of practical assembly algorithms. They quantitatively show how combining different read lengths is more cost-effective than using one length, how an optimal mixed sequencing strategy for reconstructing large novel SVs usually also gives accurate detection of SNPs/indels, how paired-end reads can improve reconstruction efficiency, and how adding in arrays is more efficient than just sequencing for disentangling some complex SVs. Our strategy should facilitate the sequencing of human genomes at maximum accuracy and low cost

A Science4Peace initiative: Alleviating the consequences of sanctions in international scientific cooperation

The armed invasion of Ukraine by the Russian Federation has adversely affected the relations between Russia and Western countries. Among other aspects, it has put scientific cooperation and collaboration into question and changed the scientific landscape significantly. Cooperation between some Western institutions and their Russian and Belarusian partners were put on hold after February 24, 2022. The CERN Council decided at its meeting in December 2023 to terminate cooperation agreements with Russia and Belarus that date back a decade. CERN is an international institution with UN observer status, and has so far played a role in international cooperation which was independent of national political strategies. We argue that the Science4Peace idea still has a great value and scientific collaboration between scientists must continue, since fundamental science is by its nature an international discipline. A ban of scientists participating in international cooperation and collaboration is against the traditions, requirements and understanding of science. We call for measures to reactivate the peaceful cooperation of individual scientists on fundamental research in order to stimulate international cooperation for a more peaceful world in the future. Specifically, we plead for finding ways to continue this cooperation through international organizations, such as CERN and JINR

Search for Doubly-Charged Higgs Boson Production at HERA

A search for the single production of doubly-charged Higgs bosons H^{\pm \pm} in ep collisions is presented. The signal is searched for via the Higgs decays into a high mass pair of same charge leptons, one of them being an electron. The analysis uses up to 118 pb^{-1} of ep data collected by the H1 experiment at HERA. No evidence for doubly-charged Higgs production is observed and mass dependent upper limits are derived on the Yukawa couplings h_{el} of the Higgs boson to an electron-lepton pair. Assuming that the doubly-charged Higgs only decays into an electron and a muon via a coupling of electromagnetic strength h_{e \mu} = \sqrt{4 \pi \alpha_{em}} = 0.3, a lower limit of 141 GeV on the H^{\pm\pm} mass is obtained at the 95% confidence level. For a doubly-charged Higgs decaying only into an electron and a tau and a coupling h_{e\tau} = 0.3, masses below 112 GeV are ruled out.Comment: 15 pages, 3 figures, 1 tabl

Forward pi^0 Production and Associated Transverse Energy Flow in Deep-Inelastic Scattering at HERA

Deep-inelastic positron-proton interactions at low values of Bjorken-x down to x \approx 4.10^-5 which give rise to high transverse momentum pi^0 mesons are studied with the H1 experiment at HERA. The inclusive cross section for pi^0 mesons produced at small angles with respect to the proton remnant (the forward region) is presented as a function of the transverse momentum and energy of the pi^0 and of the four-momentum transfer Q^2 and Bjorken-x. Measurements are also presented of the transverse energy flow in events containing a forward pi^0 meson. Hadronic final state calculations based on QCD models implementing different parton evolution schemes are confronted with the data.Comment: 27 pages, 8 figures and 3 table

Deep-Inelastic Inclusive ep Scattering at Low x and a Determination of alpha_s

A precise measurement of the inclusive deep-inelastic e^+p scattering cross section is reported in the kinematic range 1.5<= Q^2 <=150 GeV^2 and 3*10^(-5)<= x <=0.2. The data were recorded with the H1 detector at HERA in 1996 and 1997, and correspond to an integrated luminosity of 20 pb^(-1). The double differential cross section, from which the proton structure function F_2(x,Q^2) and the longitudinal structure function F_L(x,Q^2) are extracted, is measured with typically 1% statistical and 3% systematic uncertainties. The measured partial derivative (dF_2(x,Q^2)/dln Q^2)_x is observed to rise continuously towards small x for fixed Q^2. The cross section data are combined with published H1 measurements at high Q^2 for a next-to-leading order DGLAP QCD analysis.The H1 data determine the gluon momentum distribution in the range 3*10^(-4)<= x <=0.1 to within an experimental accuracy of about 3% for Q^2 =20 GeV^2. A fit of the H1 measurements and the mu p data of the BCDMS collaboration allows the strong coupling constant alpha_s and the gluon distribution to be simultaneously determined. A value of alpha _s(M_Z^2)=0.1150+-0.0017 (exp) +0.0009-0.0005 (model) is obtained in NLO, with an additional theoretical uncertainty of about +-0.005, mainly due to the uncertainty of the renormalisation scale.Comment: 68 pages, 24 figures and 18 table