<Abstract of published report>Studies on anti-von Willebrand factor (vWF) monoclonal antibody NMC-4,which inhibits both restocetin- and botrocetin-induced vWF binding to platelet glycoprotein Ib.

Keluarga merupakan lingkungan sosial pertama yang dikenal oleh manusia. Dalam keluarga, manusia belajar untuk memulai berinteraksi dengan orang lain. Sekalipun keluarga merupakan lembaga sosial pertama yang ideal guna menumbuhkembangkan potensi yang ada pada setiap individu, dalam kenyataannya keluarga seringkali menjadi wadah munculnya penyimpangan atau aktifitas ilegal sehingga menimbulkan penderitaan yang dilakukan oleh salah seorang anggota keluarga kepada anggota keluarga yang lain, misalnya adanya suatu tindak kekerasan dalam rumah tangga. Tindak kekerasan dalam rumah tangga tentu akan melibatkan sedikitnya satu orang korban. Korban perlu mendapat perlindungan untuk menghindari dampak traumatis berkepanjangan. Dalam pemberian perlindungan terhadap korban kekerasan dalam rumah tangga, terdapat perlindungan sementara yang merupakan kewajiban bagi kepolisian atau lembaga sosial maupun pihak lain untuk segera diberikan kepada korban kekerasan dalam rumah tangga. Perlindungan sementara sangat penting diberikan kepada korban kekerasan dalam rumah tangga karena jika harus menunggu penetapan perintah perlindungan dari pengadilan prosesnya akan lama. Sedangkan korban perlu mendapat perlindungan sesegera mungkin, untuk menghindari terjadinya kekerasan lebih lanjut maupun dampak traumatis yang diderita korban.Kata kunci: kekerasan dalam rumah tangga, korban, perlindungan sementara

Comparison of Physical-chemical and Mechanical Properties of Chlorapatite and Hydroxyapatite Plasma Sprayed Coatings

Chlorapatite can be considered a potential biomaterial for orthopaedic applications. Its use as plasma-sprayed coating could be of interest considering its thermal properties and particularly its ability to melt without decomposition unlike hydroxyapatite. Chlorapatite (ClA) was synthesized by a high-temperature ion exchange reaction starting from commercial stoichiometric hydroxyapatites (HA). The ClA powder showed similar characteristics as the original industrial HA powder, and was obtained in the monoclinic form. The HA and ClA powders were plasma-sprayed using a low-energy plasma spraying system with identical processing parameters. The coatings were characterized by physical-chemical methods, i.e. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy, including distribution mapping of the main phases detected such as amorphous calcium phosphate (ACP), oxyapatite (OA), and HA or ClA. The unexpected formation of oxyapatite in ClA coatings was assigned to a side reaction with contaminating oxygenated species (O2, H2O). ClA coatings exhibited characteristics different from HA, showing a lower content of oxyapatite and amorphous phase. Although their adhesion strength was found to be lower than that of HA coatings, their application could be an interesting alternative, offering, in particular, a larger range of spraying conditions without formation of massive impurities.This study was carried out under a MNT ERA-Net Project named NANOMED. The authors gratefully thank the Midi-Pyrénées region (MNT ERA Net Midi-Pyrénées Région, NANOMED2 project) and the Institute National Polytechnique de Toulouse (BQR INPT 2011, BIOREVE project) for supporting this research work, especially the financial support for research carried out in the CIRIMAT and the LGP laboratories (France), and the Basque government and Tratamientos Superficiales Iontech, S.A. for their financial and technical support under the IG-2007/0000381 grant for the development of the LEPS device and deposition of the coatings carried out in Inasmet-Tecnalia. The French industrial collaborators (TEKNIMED SA and 2PS SA) were financed by the OSEO programs

Behaviour of a biocompatible titanium alloy during orthogonal micro-cutting employing green machining techniques

The sustainability of a process is the objective of modern industries aiming to reduce waste in production, since consumers require high quality and efficiency with fair price. Thus, a good understanding of the process should be its starting point. The manufacture of dental implants is an example in which waste reduction is important for the reduction of prices due to the demand for great quality and accuracy. This study observed the behaviour of sustainable micro-cutting applied to the Ti-6Al-7Nb titanium alloy, considering the ploughing effect on minimum quantity lubrication (MQL) and high-speed machining (HSM) conditions. When compared with dry condition and low-speed cutting in orthogonal micro-cutting, the use of HSM in dry cutting was more efficient than using MQL. The dry condition presented lower surface roughness, whilst the cooled/lubricated condition presented lower burr formation.publishe