80 research outputs found

    A grid synchronization PLL with accurate extraction technique of positive/negative sequences and DC-offset under frequency drift

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    This article proposes a delayed signal-based demodulation algorithm that enables a fast and accurate extraction of the positive/negative sequences and DC-offset in the grid voltage under a frequency drift. Moreover, a simplified mathematical formalism is proposed to reduce the computational burden for real-time implementation. The algorithm is incorporated with a third-order quasi-type-1 phase-locked loop (TQT1-PLL) to estimate the grid voltage instantaneous phase-angle and frequency. The performance of the proposed PLL referred to as delayed signal demodulation based TQT1-PLL (DSD-TQT1-PLL) is evaluated under highly disturbed grid voltage conditions including DC-offset, fundamental frequency negative sequence (FFNS), characteristic harmonics, and frequency variation. The obtained simulation and experimental results show that the proposed PLL can precisely estimate the frequency and the instantaneous phase-angle of the fundamental frequency positive sequence (FFPS) without any ripple. The results showed also its superiority over the conventional and adaptive QT1-PLLs, where a better dynamic response is obtained

    Prise en charge de l’atresie choanale

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    Introduction: L’atrĂ©sie choanale est une malformation congĂ©nitale rare mais non exceptionnelle. Le but de notre travail est d’étudier les caractĂ©ristiques Ă©pidĂ©miologiques, cliniques et radiologiques de cette pathologie, et de discuter les diffĂ©rentes modalitĂ©s thĂ©rapeutiques et leurs rĂ©sultats respectifs.MatĂ©riel et mĂ©thodes: Notre Ă©tude rĂ©trospective porte sur une sĂ©rie de 12 cas d’atrĂ©sie choanale opĂ©rĂ©s dans notre service entre 2002 et 2010. Tous les patients ont bĂ©nĂ©ficiĂ© d’un examen ORL et d’une tomodensitomĂ©trie du massif facial. Tous les patients ont Ă©tĂ© opĂ©rĂ©s sous anesthĂ©sie gĂ©nĂ©rale.RĂ©sultats: L’ñge moyen Ă©tait de 10,7 ans (3 jours - 31 ans) et le sex-ratio Ă©tait de 2. L’atteinte Ă©tait unilatĂ©rale dans 66,6% et bilatĂ©rale dans 33,3% des cas. Dans 16% des cas, l’atrĂ©sie rentrait dans le cadre d’un syndrome polymalformatif. La technique opĂ©ratoire utilisĂ©e Ă©tait la voie  endoscopique dans 10 cas et la voie transpalatine dans 2 cas. Le taux de succĂšs global Ă©tait de 75%. Trois cas de rĂ©cidive ont Ă©tĂ© notĂ©s. Ils ont Ă©tĂ© rĂ©opĂ©rĂ©s par voie endonasale.Conclusion: L’endoscopie nasale et la TDM permettent le diagnostic positif de l’atrĂ©sie choanale. Le traitement de rĂ©fĂ©rence actuellement est la chirurgie par voie endonasale.Mots-clĂ©s: atrĂ©sie choanale, malformation, obstruction nasale, endoscopie, tomodensitomĂ©trie, chirurgie endonasal

    Bioactive Secondary Metabolites from a New Terrestrial Streptomyces sp. TN262

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    During our search for Streptomyces spp. as new producers of bioactive secondary metabolites, the ethyl acetate extract of the new terrestrial Streptomyces isolate TN262 delivered eight antimicrobially active compounds. They were identified as 1-acetyl-ÎČ-carboline (1), tryptophol (2), cineromycin B (3), 2,3-dihydrocineromycin B (4), cyclo-(tyrosylprolyl) (5), 3-(hydroxyacetyl)-indole (6), brevianamide F (7), and cis-cyclo-(l-prolyl-l-leucyl) (8). Three further metabolites were detected in the unpolar fractions using GC–MS and tentatively assigned as benzophenone (9), N-butyl-benzenesulfonamide (10), and hexanedioic acid-bis-(2-ethylhexyl) ester (11). This last compound is known as plasticizer derivatives, but it has never been described from natural sources. In this article, we describe the identification of the new Streptomyces sp. isolate TN262 using its cultural characteristics, the nucleotide sequence of the corresponding 16S rRNA gene and the phylogenetic analysis, followed by optimization, large-scale fermentation, isolation of the bioactive constituents, and determination of their structures. The biological activity of compounds (2), (3), (4), and those of the unpolar fractions was addressed as well

    Oral HPV infection and MHC class II deficiency (A study of two cases with atypical outcome)

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    <p>Abstract</p> <p>Background</p> <p>Major histocompatibility complex class II deficiency, also referred to as bare lymphocyte syndrome is a rare primary Immunodeficiency disorder characterized by a profondly deficient human leukocyte antigen class II expression and a lack of cellular and humoral immune responses to foreign antigens. Clinical manifestations include extreme susceptibility to viral, bacterial, and fungal infections. The infections begin in the first year of life and involve usually the respiratory system and the gastrointestinal tract. Severe malabsorption with failure to thrive ensues, often leading to death in early childhood. Bone marrow transplantation is the curative treatment.</p> <p>Case reports</p> <p>Here we report two cases with a late outcome MHC class II deficiency. They had a long term history of recurrent bronchopulmonary and gastrointestinal infections. Bone marrow transplantation could not be performed because no compatible donor had been identified. At the age of 12 years, they developed oral papillomatous lesions related to HPV (human papillomavirus). The diagnosis of HPV infection was done by histological examination. HPV typing performed on the tissue obtained at biopsy showed HPV type 6. The lesions were partially removed after two months of laser treatment.</p> <p>Conclusions</p> <p>Viral infections are common in patients with MHC class II and remain the main cause of death. Besides warts caused by HPV infection do not exhibit a propensity for malignant transformation; they can cause great psychosocial morbidity.</p

    Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

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    Some issues on the coherence of min-based possibilistic causal Networks

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    Architecture d’agent hybride Ă  comportement tempĂ©ramental et Rationnel

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    International audienceLe présent ouvrage s'intéresse à la modélisation d'agent hybride doté d'un certain niveau d'intelligence et de sa mise en oeuvre dans un processus de négociation automatisée. Incorporant un modÚle paramétrable de comportement tempéramental approchant les postures telles que la conciliation, l'agressivité ou neutralité, et développant une aptitude rationnelle de collaboration, de partage des gains ou d'intransigeance, un tel agent offre le potentiel d'une prise en compte de l'impact de la personnalité dans un processus de négociation à travers une mise en oeuvre virtuelle de celle-ci. Les concepts régissant de tels agents hybrides amorcent les perspectives d'une négociation automatisée à base d'agents virtuels. L'ouvrage rapporte également une étude de cas simulant une négociation bilatérale portant sur la recherche d'un accord sur le prix d'une transaction (achat-vente) impliquant un agent conventionnel (à base du modÚle temporel de Faratin) et d'un agent hybride incorporant les concepts développés dans cet ouvrage
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