541 research outputs found
Biological Role of Cobalt(II), Copper(II) and Nickel(II) Metal Ions on the Antibacterial Properties of Some Nicotinoyl-Hydrazine Derived Compounds
Several cobalt(II), copper(II) and nickel(II) complexes of nicotinoylhydrazine-derived compounds were prepared and characterised by physical, spectral and analytical data. These compounds and their complexes have proven to be antibacterial. The screening data show the metal complexes to be more potential/bactericidal than the uncomplexed compounds against one or more bacterial species
Spectral, Magnetic and Biological Studie on Some Bivalent 3d Metal Complexes of Hydrazine Derived Schiff-Base Ligands
Metal(II) complexes of hydrazine derived Schiff-base ligands of the type M(L)2Cl2 where M = Co, Cu, Ni and Zn and L = L1 and L2 have been prepared and characterised by molar conductance, magnetic moment, elemental analysis and electronic, IR, H-NMR and 13C spectral data.The different modes of chelation of the ligands and their comparative biological properties against different bacterial species are reported
Synthesis, Characterization and Role of Anions (Nitrate, Sulphate, Oxalate and Acetate) \in the Biological Activity of Hydrazine Derived Compounds and Their Metal Chelates
Hydrazine derived compounds and its Co(II), Cu(II) and Ni(II) chelates having the same metal ion but different anions (e.g., nitrate, sulphate, oxalate and acetate) have been synthesised and
characterised by their physical, spectral and analytical data. In order to evaluate the participating role of anions in the antibacterial activity, these synthesised ligands and its metal chelates have been
screened against bacterial species such as Staphylococcus aureous, pseudomonas aeruginosa, Klebsiella pneumonae and Proteus vulgarus, and the results are reported
Studies on Some Biologically Cobalt(II), Copper(II) and Zinc(II) Complexes With ONO, NNO and SNO Donor Pyrazinoylhydrazine-Derived Ligands
Biologically active complexes of Co(II), Ni(II), Cu(II) and Zn(II) with novel ONO, NNO and
SNO donor pyrazinoylhydrazine-derived compounds have been prepared and characterized on the basis of
analytical data and various physicochemical studies. Distorted octahedral structures for all the complexes
have been proposed. The synthesized ligands and their complexes have been screened for their antibacterial
activity against bacterial species Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Klebsiella pneumonae. The activity data show the metal complexes to be more active than the parent free
ligands against one or more bacterial species
Synthesis, Ligational and Biological Properties of Cobalt(II), Copper(II), Nickel(II) and Zinc(II) Complexes With Pyrazinedicarboxaimide Derived Furanyl, Thienyl and Pyrrolyl Compounds
Preparation, ligational and biological properties of some pyrazinedicarboxaimide derived
furanyl, thienyl and pyrrolyl compounds with Co(ll), Cu(ll), Ni(ll) and Zn(ll) metals are
described. Magnetic moments, electronic, infrared, nuclear magnetic resonance spectra and
elemental analysis data indicate that co-ordination of the ligands with the metal ions take
place through the pyrazine ring nitrogen, azomethine nitrogen and heteroatom of
heterocyclic ring system. The compounds are all novel and are proposed to possess an
octahedral geometry for Co(ll) and Ni(ll), and a distorted octahedral geometry for Cu(ll) and
Zn(ll) complexes. The comparative biological properties of the title ligands and their metal
chelates against different bacterial species are also described
2-(4-Chlorophenyl)-1,5-diphenyl-3-tosylimidazolidin-4-one
In the title compound, C28H23ClN2O3S, the central imidazolidine ring adopts a twisted conformation and the S atom has distorted tetrahedral geometry. The crystal packing is stabilized by C—H⋯O, C—H⋯π and π–π interactions [centroid–centroid distance = 3.8302 (10) Å]
Prediction of Malaysian exchange rate using microstructure fundamental and commodities prices: a machine learning method
The key objective of this research is to investigate the short run dynamics of the exchange rate using commodity prices and microstructure market variables for developing economies, Malaysia. The analysis of the literature revealed different school of thought where one claims the strong correlation among the variables while other significantly reject the relationship. There is mixed results that support and reject the accurate forecasting of the exchange rate through different determinants. Therefore, in this study the machine learning approach is applied to perform the extensive experiments and investigate the relationship between the commodity prices, bid-ask spread and exchange rate. Three techniques were selected from the machine learning i.e. artificial neural network, RandomForest and support vector machine. The experimental results revealed that randomforest perform better than SVM and ANN, both in the performance and accuracy. Thus, the exchange rate can be predicted will reasonable accuracy using the commodity prices in the combination of the bid-ask spread. Thus, the policy maker can be utilized these results for strategies development, corporate planning and building investment plan
Emerging Pharmacologic Targets in Cerebral Cavernous Malformation and Potential Strategies to Alter the Natural History of a Difficult Disease: A Review
Adsorption site, orientation and alignment of NO adsorbed on Au(100) using 3D-velocity map imaging, X-ray photoelectron spectroscopy and density functional theory
Nitric oxide adsorption on a Au(100) single crystal has been investigated to identify the type of adsorption, the adsorption site, and the orientation and alignment of the adsorbed NO relative to the surface. This was done using a combination of 3D-surface velocity map imaging, near-ambient pressure X-ray photoelectron spectroscopy, and density functional theory. NO was observed to be molecularly adsorbed on gold at ∼200 K. Very narrow angular distributions and cold rotational distributions of photodesorbed NO indicate that NO adsorbs on high-symmetry sites on the Au crystal, with the N-O bond axis close to the surface normal. Our density functional theory calculations show that NO preferentially adsorbs on the symmetric bridge (2f) site, which ensures efficient overlap of the NO π* orbital with the orbitals on the two neighbouring Au atoms, and with the N-O bond axis aligned along the surface normal, in agreement with our conclusions from the rotational state distributions. The combination of XPS, which reveals the orientation of NO on gold, with 3D-surface velocity map imaging and density functional theory thus allowed us to determine the adsorption site, orientation and alignment of nitric oxide adsorbed on Au(100)
Chronic nonpuerperal uterine inversion and necrosis: a case report
<p>Abstract</p> <p><b>Introduction</b></p> <p>Inversion of the non-pregnant uterus is rare.</p> <p><b>Case presentation</b></p> <p>A 56-year-old African American woman presented to our emergency center with complaints of a mass protruding from her vagina. She subsequently underwent vaginal myomectomy, abdominal hysterectomy and bilateral salpingo-oophorectomy. Pathologic examination revealed a necrotic fibroid and endometrium. At the time of laparotomy an inverted uterus was diagnosed when a 3 cm dimple containing bilateral round ligaments, infundibulopelvic ligaments and bladder was observed.</p> <p>Conclusion</p> <p>Chronic nonpuerperal inversion of the uterus is rare. Infection should be suspected and appropriate broad spectrum antibiotics begun while planning surgery. An attempt at vaginal restoration and removal is difficult. Abdominal hysterectomy may be necessary taking care to locate the distal urinary collecting system.</p
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