A study on health profile of geriatric population in an urban slum of bijapur

Background: Advances in medical field have increased the longevity of people by reducing morbidity and mortality to a great extent. With the increase in longevity, problems related to old age have also increased. These problems are more confounded by social factors. Objective: To assess the various health problems faced by elderly people and suggest the remedial measures so that effective preventive and promotive measures can be implemented. Methodology: Community based cross-sectional study of the elderly persons residing in an urban slum of Bijapur. Results: Among acute health problems most common were arthritis (39%) and bronchitis (20.8%). Most common chronic illness observed was respiratory illness 19% (COPD and asthma) fallowed by visual impairment (11.5%), arthritis (11.1%), and hypertension (9.1%) Mini Mental State Examination (MMSE) showed that majority of respondents 297 (60%) were having the normal score. Conclusion: The pattern of geriatric health problems have different characteristics and hence require a specific type of screening programme based on the finding of various geriatric health studies

Mitochondrial DNA marker reveals shallow genetic structuring in Priacanthus hamrur (Forsskål, 1775) along the Indian coast

Priacanthus hamrur (Forsskål, 1775), a marine perch belonging to the family Priacanthidae commonly known as “bulls eye” has started emerging as an important fishery resource in the trawl landings along both the west and east coasts of India. In the present study, genetic stock structure of P. hamrur inhabiting Indian coastal waters was ascertained with mitochondrial DNA sequences from the cytochrome b (cyt-b) gene using samples of the species collected in two samplings from five different geographical locations, viz. Chennai and Visakhapatnam (east coast) and Cochin, Mumbai and Veraval (West coast). Partial sequence of cyt-b gene of P. hamrur from 5 representative regions along the coastal zones was amplified by PCR. The cyt- b marker revealed high haplotype diversity coupled with very low nucleotide diversity within each population, as well as low genetic distance, high gene flow, and high mitochondrial DNA similarity among all five populations. Phylogenetic trees and pairwise analyses demonstrated a very small divergence (0.43-0.64%) between the populations, suggesting the lack of population subdivisions. The overall lack of genetic subdivision among samples was also detected by the analysis of molecular variance, and pairwise FST values. Furthermore, the results of this study revealed a pattern of high nucleotide homology among the adjacent populations, and a small number of nucleotide changes among disjunct populations, leading us to conclude that there is a genetic connectivity among the populations of P.hamrur inhabiting the coastal waters of India

from pediococcus pentosaceus isolated from Kurdai

Kurdai is a traditional fermented whole wheat snack food, native to Maharashtra and parts of Gujarat. The microbes responsible for kurdai fermentation have been successfully isolated and identified as Leuconostoc lactis, Pedicoccus pentosaceus, Enterococcus faecium, Staphylococcus hominis, Klebsiella pneumonia and Lactobacillus plantarum. Pedicoccus pentosaceus one of microbes responsible for kurdai fermentation were identified. In the present work, Pedicoccus pentosaceus was explored for the production of pediocin which is a Class II bacteriocin produced by lactic acid bacteria, because they are heat stable and non-modified lantibiotics. Bacteriocins have been drawing the attention of the food industry because of their increased specificity and effectiveness at low concentrations in order to prevent the development of pathogens. The activity of pediocin was evaluated using various commercial strains as indicators such as Escherichia coli MTCC 40, Bacillus cereus MTCC 1272, Leuconostoc mesenteroides NCIM 2198, Lactobacillus fermentum NCIM 2165 and Lactobacillus helveticus NCIM 2733. It was shown that the highest pediocin activity was expressed against Lactobacillus helveticus NCIM 2733 with 4.89 + 0.13 Activity Units (AU)/mL being produced. Pediocin production was then optimized by controlling the incubation time, temperature seed age, inoculum density and initial pH of the growth media.Fil: Pavitra, Krishna Kumar. Institute of Chemical Technology. Food Engineering and Technology Department; IndiaFil: Deshmukh, Shrinivas R.. Institute of Chemical Technology. Food Engineering and Technology Department; IndiaFil: Sonawane, Sachin K.. Institute of Chemical Technology. Food Engineering and Technology Department; IndiaFil: Leblanc, Jean Guy Joseph. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucuman. Centro de Referencia Para Lactobacilos; Argentina. Universidad Nacional de Tucuman. Facultad de Medicina; ArgentinaFil: Arya, Shalini S.. Institute of Chemical Technology. Food Engineering and Technology Department; Indi

Morphometric and meristic variation of congeneric sciaenid fishes Otolithes cuvieri Trewavas, 1974 and Otolithes ruber (Schneider, 1801) from Maharashtra, west coast of India

Two closely related species Otolithes cuvieri, Trewavas, 1974 and Otolithes ruber, (Schneider, 1801) have been differentiated based on morphometric and meristic traits. A simple yet useful criterion based on a pair of canine teeth present on the upper and lower jaw as well as position of the mouth is currently used to differentiate two congeneric sciaenid fish species the O. cuvieri and O. ruber. Findings of the present study indicated that simply two morphometric and meristic characters are sufficient to differentiate these two species. MANOVA (Multivariate analysis of variance) and stepwise discriminant function were used to decide the morphometric traits, significant for differentiation of the species of family Sciaenidae. Discriminant function analysis revealed that 98 % of the species were correctly classified based on five morphometric characters namely Pre-pectoral fin length (PPFL), Pre-anal fin length (PAL), Post orbital head length (POHL), Post anal fin length (POAL) and Body depth (BD). The m-transformed morphometric traits were found to be useful tools in generating canonical variables in differentiating the species. The first canonical variables showed altogether 98 % variance. The scatter plots by first three canonical variables have well differentiated the species. Two meristic characters such as the number of gillrakers present on lower limb of first gill arch and figure of arborescent appendages on the swim bladder are important in differentiation of these species

Multipurpose Pedal Operated Power Generation and Water Pumping

Diversion is required for basically right success, for the traverse of endeavor ton of constrain is used by using human which is misused. This waste vitality is used for the workplace cycle and to run pump manhandle our attempt appear. We tend to waste gushing imperativeness into a fundamental power. With eco-pleasing methodology In this venture work an endeavor has been made to improvement of theoretical model of water pumping and battery charging cross mentor that is easy to use, easy to attempt and do work out, spare & stores the vitality of the clients muscle endeavors. Once the human works the pedal, the pump is propelled and consequently the water is wired from ground sump to the tank. Subsequently no extra water is squandered. In our venture a demo of this is frequently appeared. At indistinguishable time the associated generator (i.e., is mounted near the V-belt) works and subsequently the vitality is recover into current.This is often wont to charge the mobile exploitation mobile charging circuit. It additionally includes a separate unit known as generator, connected to back wheel of the cycle as just in case of pump through V-belt and simple machine affiliation. This generator additionally converts energy into associate current. The generated current is hold on in battery with the assistance of wires. The stored electrical energy is employed after we are required

An overview of health concerns among elderly population

Background: Urbanisation, nuclearisation of family, migration, and dual career families are making care of the elderly more and more of a personal and social problem in India. Objective: Assess the concerns about health issues among elderly people. Methodology: Community based cross-sectional study. Results: 64.4% of the elders were treated well and about 22.9% were treated very well during illness. 86.3% were consulted during illness. Son was the care taker in 55.6% of study subjects. 70.6% of elderly were consulted to allopathic practitioners / Govt Hospitals. Conclusion: It is the responsibility of family to look after elderly in respectful manner, especially during illness. The government should frame policies and provide social and economical security to elders

Preparation and Characterization of Solid Lipid Nanoparticles Loaded with Cisplatin

Cisplatin (Cis diaminedichloro platinum) was the first platinum drug to be used as an anticancer drug, and it is widely used in the treatment of testicular, head, neck, ovarian and lung cancer. The use of Cisplatin is limited due to its intrinsic and acquired resistance and severe side effects such as chronic neurotoxicity and nephrotoxicity. The colloidal carriers such as emulsion, liposomes, polymeric nanoparticles have been extensively studied to overcome above limitations. The solid lipid nanoparticles (SLNs), amongst other colloidal carriers, were found to be an ideal carrier for lipophillic drug for better stability and release retardation. Cisplatin loaded solid lipid nanoparticles was prepared by microemulsion technique. Stearic acid was used as lipid. The other excipients were used as DPPG, Soya lecithin and Poloxamer P407  and acidic buffer  PH4. Also used Probe sonication for 10 min at 79 Amplitude. Cisplatin SLNs Batch C13 showed particle size of 119.23±1.52 nm, Zeta potential of -37.33±2.47 mV, % Entrapment efficiency of  90.2 ± 2.1 %., % Drug loading capacity of 1.62 ± 1.34 %., The TEM study of optimized Cisplatin SLN illustrated the spherical shape of nanoparticles. Total release amount of Cisplatin was 82.62± 2.04 % after 48 hrs. The formulation performed kinetics study followed Peppas plot equation The SLNs of Cisplatin met all the requirements of a colloidal drug delivery system. They had particle size in nanosize; their size distribution was narrow and all the particles were in spherical shape and stable. Keywords: Cisplatin, Solid Lipid nanoparticles, zeta potential, Particle size, Transmission electron Microscopy

Evidence for an FU Orionis-like Outburst from a Classical T Tauri Star

We present pre- and post-outburst observations of the new FU Orionis-like young stellar object PTF 10qpf (also known as LkHa 188-G4 and HBC 722). Prior to this outburst, LkHa 188-G4 was classified as a classical T Tauri star on the basis of its optical emission-line spectrum superposed on a K8-type photosphere, and its photometric variability. The mid-infrared spectral index of LkHa 188-G4 indicates a Class II-type object. LkHa 188-G4 exhibited a steady rise by ~1 mag over ~11 months starting in Aug. 2009, before a subsequent more abrupt rise of > 3 mag on a time scale of ~2 months. Observations taken during the eruption exhibit the defining characteristics of FU Orionis variables: (i) an increase in brightness by > 4 mag, (ii) a bright optical/near-infrared reflection nebula appeared, (iii) optical spectra are consistent with a G supergiant and dominated by absorption lines, the only exception being Halpha which is characterized by a P Cygni profile, (iv) near-infrared spectra resemble those of late K--M giants/supergiants with enhanced absorption seen in the molecular bands of CO and H_2O, and (v) outflow signatures in H and He are seen in the form of blueshifted absorption profiles. LkHa 188-G4 is the first member of the FU Orionis-like class with a well-sampled optical to mid-infrared spectral energy distribution in the pre-outburst phase. The association of the PTF 10qpf outburst with the previously identified classical T Tauri star LkHa 188-G4 (HBC 722) provides strong evidence that FU Orionis-like eruptions represent periods of enhanced disk accretion and outflow, likely triggered by instabilities in the disk. The early identification of PTF 10qpf as an FU Orionis-like variable will enable detailed photometric and spectroscopic observations during its post-outburst evolution for comparison with other known outbursting objects.Comment: 14 pages, 11 figures, ApJ accepte

Real-Time Detection and Rapid Multiwavelength Follow-up Observations of a Highly Subluminous Type II-P Supernova from the Palomar Transient Factory Survey

The Palomar Transient Factory (PTF) is an optical wide-field variability survey carried out using a camera with a 7.8 square degree field of view mounted on the 48-in Oschin Schmidt telescope at Palomar Observatory. One of the key goals of this survey is to conduct high-cadence monitoring of the sky in order to detect optical transient sources shortly after they occur. Here, we describe the real-time capabilities of the PTF and our related rapid multiwavelength follow-up programs, extending from the radio to the gamma-ray bands. We present as a case study observations of the optical transient PTF10vdl (SN 2010id), revealed to be a very young core-collapse (Type II-P) supernova having a remarkably low luminosity. Our results demonstrate that the PTF now provides for optical transients the real-time discovery and rapid-response follow-up capabilities previously reserved only for high-energy transients like gamma-ray bursts.Comment: ApJ, in press; all spectroscopic data available from the Weizmann Institute of Science Experimental Astrophysics Spectroscopy System (WISEASS; http://www.weizmann.ac.il/astrophysics/wiseass/