81 research outputs found

    High Grade Phosphate from Syrian Phosphate at Eastern Mines

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    Syria is one of the major sedimentary rock phosphate producing countries in the Middle East from the Khneifiss, Eastern "A" and Eastern "B" mines. The phosphate rock of Syrian mines is being upgraded by increasing P205 content to higher values (>28%) suitable for fertilizers and other industries. But it is not always possible to do so due to interlocking of other contents such as the higher CaO/P,05 ratio, and the high chlorine and R,03 (Fe203+A1203) contents

    ENERGY MINIMIZATION FOR IDENTIFICATION OF BANDING PATTERN IN CHROMOSOMES USING OPTIMIZED GRAPH CUT ALGORITHM

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    Intensity inhomogeneity is a significant cause in reducing the accuracy of image segmentation. This paper proposes an algorithm for identification of bands in chromosomes using graph cut segmentation that uses global and local image statistics. The global energy is an estimate of the intensity distribution of the image and background and local energy provide the information related with neighboring pixels that eliminates the impact of intensity inhomogeneities. Efficient energy minimization helps in better pixel labeling and this is done by optimized Graph cut process. The shape prior of the band at each location of the image is considered with shape probability energy functions. The experimental results demonstrate that the approach is robust and efficient in detecting the band information in chromosomes to a larger extent

    Inclusion properties of certain subclasses of analytic functions defined by generalized Salagean operator

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    Let AA denote the class of analytic functions with the normalization f(0)=f′(0)−1=0f(0)=f^{\prime }(0)-1=0 in the open unit disc U=\{z:\left\vert z\right\vert <1\}.  Set fλn(z)=z+∑k=2∞[1+λ(k−1)]nzk(n∈N0; λ≥0; z∈U),f_{\lambda }^{n}(z)=z+\sum_{k=2}^{\infty }[1+\lambda (k-1)]^{n}z^{k}\quad(n\in N_{0};\ \lambda \geq 0;\ z\in U), and define fλ,μnf_{\lambda ,\mu }^{n} in terms of the Hadamard product f_{\lambda }^{n}(z)\ast f_{\lambda ,\mu }^{n}=\frac{z}{(1-z)^{\mu }}\quad (\mu >0;\ z\in U). In this paper, we introduce several subclasses of analytic functions defined by means of the operator Iλ,μn:A⟶AI_{\lambda ,\mu }^{n}:A\longrightarrow A, given by I_{\lambda ,\mu }^{n}f(z)=f_{\lambda ,\mu }^{n}(z)\ast f(z)\quad (f\in A;\ n\in N_{0;}\ \lambda \geq 0;\ \mu >0). Inclusion properties of these classes and the classes involving the generalized Libera integral operator are also considered

    THE EFFECT OF A PERIPHERAL NOREPINEPHRINE PROTOCOL ON CENTRAL LINE UTILIZATION IN A SURGICAL ICU

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    INTRODUCTION: Central venous catheters (CVC) are associated with various complications. In several studies, the use of vasopressors through peripheral venous catheters (PVC) obviated the need for CVC insertion in 34-87% of patients. Although evidence indicates that the peripheral administration of vasopressors is safe, most health systems currently use protocols that favor the use of CVC over PVC. We proposed a quality improvement study evaluating the use of a protocol for the peripheral administration of a dilute norepinephrine solution (16 mcg/ml) in the surgical intensive care unit (SICU). METHODS: This was a retrospective quality improvement study conducted at Henry Ford Hospital in Detroit, MI. We included 100 patients that were admitted to the SICU between June and December 2021 and received dilute norepinephrine for any cause through a PVC under our prespecified protocol. Guidelines for CVC insertion were present in the protocol to assist clinicians. An extravasation protocol was instituted which included application of 2% nitroglycerin ointment. The primary endpoint evaluated was the number of patients in which a CVC was placed, regardless of the cause, within 24 hours of discontinuation of norepinephrine through the PVC. Secondary endpoints included the indication for central line placement, dose of norepinephrine infused, duration of norepinephrine infusions, gauge and location of the PVC, frequency of extravasation events, and tissue injury. RESULTS: Out of the 100 included in the study 51 patients (51%) did not receive a CVC, and 60 patients (60%) did not receive a CVC within the first 24 hours of discontinuation of peripheral norepinephrine. Norepinephrine extravasation was noted in 6 patients (6%). These incidents were successfully managed with nitroglycerin (2%) ointment. CONCLUSIONS: We demonstrated that administration of diluted norepinephrine through a PVC following a protocol in the SICU was associated with a reduction in CVC placement. The incidence of extravasation of norepinephrine was rare. Careful assessment of the PVC allowed for early treatment with topical nitroglycerine and no harm was identified to any patient

    Analysis of protein carbonylation - pitfalls and promise in commonly used methods

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    Abstract Oxidation of proteins has received a lot of attention in the last decades due to the fact that they have been shown to accumulate and to be implicated in the progression and the patho-physiology of several diseases such as Alzheimer, coronary heart diseases, etc. This has also resulted in the fact that research scientist became more eager to be able to measure accurately the level of oxidized protein in biological materials, and to determine the precise site of the oxidative attack on the protein, in order to get insights into the molecular mechanisms involved in the progression of diseases. Several methods for measuring protein carbonylation have been implemented in different laboratories around the world. However, to date no methods prevail as the most accurate, reliable and robust. The present paper aims at giving an overview of the common methods used to determine protein carbonylation in biological material as well as to highlight the limitations and the potential. The ultimate goal is to give quick tips for a rapid decision making when a method has to be selected and taking into consideration the advantage and drawback of the methods

    The CHEMDNER corpus of chemicals and drugs and its annotation principles

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    The automatic extraction of chemical information from text requires the recognition of chemical entity mentions as one of its key steps. When developing supervised named entity recognition (NER) systems, the availability of a large, manually annotated text corpus is desirable. Furthermore, large corpora permit the robust evaluation and comparison of different approaches that detect chemicals in documents. We present the CHEMDNER corpus, a collection of 10,000 PubMed abstracts that contain a total of 84,355 chemical entity mentions labeled manually by expert chemistry literature curators, following annotation guidelines specifically defined for this task. The abstracts of the CHEMDNER corpus were selected to be representative for all major chemical disciplines. Each of the chemical entity mentions was manually labeled according to its structure-associated chemical entity mention (SACEM) class: abbreviation, family, formula, identifier, multiple, systematic and trivial. The difficulty and consistency of tagging chemicals in text was measured using an agreement study between annotators, obtaining a percentage agreement of 91. For a subset of the CHEMDNER corpus (the test set of 3,000 abstracts) we provide not only the Gold Standard manual annotations, but also mentions automatically detected by the 26 teams that participated in the BioCreative IV CHEMDNER chemical mention recognition task. In addition, we release the CHEMDNER silver standard corpus of automatically extracted mentions from 17,000 randomly selected PubMed abstracts. A version of the CHEMDNER corpus in the BioC format has been generated as well. We propose a standard for required minimum information about entity annotations for the construction of domain specific corpora on chemical and drug entities. The CHEMDNER corpus and annotation guidelines are available at: http://www.biocreative.org/resources/biocreative-iv/chemdner-corpus
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