Review: Purposeful Memoir as a Quest for a Thriving Future: Inspiration for Writers and Seekers by Jennifer Browdy

Book Review: Jennifer Browdy’s Purposeful Memoir as a Guest for a Thriving Future: Inspiration for Writers and Thinkers (Green Fire Press, 2021), a guidebook for writers seeking to heal through the study of the self. Browdy is Professor of Cmparative Literature and Media Arts at Bard College at Simon\u27s Rock

Editor\u27s Note

Editor\u27s Note, Early College Folio, Volume 1, Issue 2 (May 2022

The Portal Theory Supported by Venous Drainage–Selective Fat Transplantation

OBJECTIVE The "portal hypothesis" proposes that the liver is directly exposed to free fatty acids and cytokines increasingly released from visceral fat tissue into the portal vein of obese subjects, thus rendering visceral fat accumulation particularly hazardous for the development of hepatic insulin resistance and type 2 diabetes. In the present study, we used a fat transplantation paradigm to (artificially) increase intra-abdominal fat mass to test the hypothesis that venous drainage of fat tissue determines its impact on glucose homeostasis. RESEARCH DESIGN AND METHODS Epididymal fat pads of C57Bl6/J donor mice were transplanted into littermates, either to the parietal peritoneum (caval/systemic venous drainage) or, by using a novel approach, to the mesenterium, which confers portal venous drainage. RESULTS Only mice receiving the portal drained fat transplant developed impaired glucose tolerance and hepatic insulin resistance. mRNA expression of proinflammatory cytokines was increased in both portally and systemically transplanted fat pads. However, portal vein (but not systemic) plasma levels of interleukin (IL)-6 were elevated only in mice receiving a portal fat transplant. Intriguingly, mice receiving portal drained transplants from IL-6 knockout mice showed normal glucose tolerance. CONCLUSIONS These results demonstrate that the metabolic fate of intra-abdominal fat tissue transplantation is determined by the delivery of inflammatory cytokines to the liver specifically via the portal system, providing direct evidence in support of the portal hypothesis

Naturaleza analógica: obra en proceso

Somos cuatro artistas de la ciudad de Rosario, Santa Fe. Desde mediados del año 2014 estamos trabajando en una obra de danza/ performance llamada Naturaleza analógica con la cual ganamos el concurso Cosecha Escénica 2014 de la Municipalidad de nuestra ciudad, premio que nos posibilitó, entre otras cosas dedicarnos a trabajar intensamente junto a otras profesionales como Fabiana Capriotti, Marina Giancaspro y Ana Varela. Propuesta que se da en el marco de un devenir constante del presente, jugando con la luz y la oscuridad, proyecciones de imágenes aleatorias, cuerpos- movimiento y sonidos que se generan del mismo hacer y del contexto. Es una obra abierta, que danza entre lo íntimo y lo público, que está todo el tiempo a la expectativa de lo inesperado, que muta, que se mueve, que se alimenta. Específicamente, Naturaleza analógica es una obra / performance de danza en la cual la significación, el espacio escénico y los relatos dramáticos no preexisten, sino que se conforman y entretejen en la interacción de todos los elementos que intervienen en la propuesta.Eje 1: Investigaciones sobre procesos creativos. Talleres, obras y performancesFacultad de Humanidades y Ciencias de la Educació

Accumulation and toxicity of monoaromatic petroleum hydrocarbons in early life stages of cod and haddock

A multitude of recent studies have documented the detrimental effects of crude oil exposure on early life stages of fish, including larvae and embryos. While polycyclic aromatic hydrocarbons (PAHs), particularly alkyl PAHs, are often considered the main cause of observed toxic effects, other crude oil derived organic compounds are usually overlooked. In the current study, comprehensive two-dimensional gas chromatography coupled to mass spectrometry was applied to investigate the body burden of a wide range of petrogenic compounds in Atlantic haddock (Melanogrammus aeglefinus) and cod (Gadus morhua) embryos that had been exposed to sublethal doses of dispersed crude oil. Several groups of alkylated monoaromatic compounds (e.g. alkyl tetralins, indanes and alkyl benzenes), as well as highly alkylated PAHs, were found to accumulate in the fish embryos upon crude oil exposure. To investigate the toxicity of the monoaromatic compounds, two models (1-isopropyl-4-methyltetralin and 1-isopropyl-4-methylindane) were synthesized and shown to bioaccumulate and cause delayed hatching in developing embryos. Minor developmental effects, including craniofacial and jaw deformations and pericardial edemas, were also observed at the highest studied concentrations of the alkylindane.acceptedVersio

Nurses\u27 Alumnae Association Bulletin, June 1969

Alumnae President\u27s Message Officers and Chairmen Financial Report Progressive Changes at Jefferson School of Nursing Report Student Activities School of Practical Nursing Report Jefferson Expansion Report Clerk-Typist Report Committee Reports Resume of Alumnae Meetings Class News 1969 CLINIC Correspondence Notice

Many people in Scotland now benefit from anticipatory care before they die: an after death analysis and interviews with general practitioners

Background Key Information Summaries (KIS) were introduced throughout Scotland in 2013 so that anticipatory care plans written by general practitioners (GPs) could be routinely shared electronically and updated in real time, between GPs and providers of unscheduled and secondary care. Aims We aimed to describe the current reach of anticipatory and palliative care, and to explore GPs\u27 views on using KIS. Methods We studied the primary care records of all patients who died in 2014 in 9 diverse Lothian practices. We identified if anticipatory or palliative care had been started, and if so how many weeks before death and which aspects of care had been documented. We interviewed 10 GPs to understand barriers and facilitating factors. Results Overall, 60% of patients were identified for a KIS, a median of 18 weeks before death. The numbers identified were highest for patients with cancer, with 75% identified compared with 66% of those dying with dementia/frailty and only 41% dying from organ failure. Patients were more likely to die outside hospital if they had a KIS. GPs identified professional, patient and societal challenges in identifying patients for palliative care, especially those with non-cancer diagnoses. Conclusions GPs are identifying patients for anticipatory and palliative care more equitably across the different disease trajectories and earlier in the disease process than they were previously identifying patients specifically for palliative care. However, many patients still lack care planning, particularly those dying with organ failure