Stochastic models for atomic clocks

For the atomic clocks used in the National Bureau of Standards Time Scales, an adequate model is the superposition of white FM, random walk FM, and linear frequency drift for times longer than about one minute. The model was tested on several clocks using maximum likelihood techniques for parameter estimation and the residuals were acceptably random. Conventional diagnostics indicate that additional model elements contribute no significant improvement to the model even at the expense of the added model complexity

Analysis of Groundwater Level Changes, Surface Water Conditions, and Water Use in the Greater Barrington Region, 2014–2019

The Barrington area is dependent on shallow groundwater resources for water supply and is unusual in that much of the water demand required by its residents is met by private wells as opposed to centralized community water systems. The Barrington Area Council of Governments (BACOG) supports a groundwater and surface water monitoring program consisting of continuous and periodic water level measurements in local streams and in the shallow sand and gravel aquifer system (Henry Formation). BACOG also leads a yearly mass measurement of water levels at municipal wells within and surrounding the BACOG study area. We developed potentiometric surfaces (maps that represent aquifer water level elevations) for the sand and gravel aquifer system for the years 2014–2019 using geographic information system (GIS) interpolation tools, and from those developed potentiometric change maps. We also analyzed trends in baseflow conditions using United States Geological Survey (USGS) streamgage data and water use from the sand and gravel and shallow bedrock aquifers using Illinois Water Inventory Program (IWIP) data. The potentiometric surfaces show a consistent groundwater high in the western half of the BACOG study area due to the Henry Formation being at or near the land surface. Resultsfrom this study indicate that water levels in the sand and gravel aquifer within the BACOG study area have generally increased over the five-year study period. Water levels increased on average: 1) by around 5 feet at the continuously monitored USGS sites, 2) by 5.8 feet at the Illinois State Geological Survey monitoring wells, and 3) by over 5 feet at municipal wells. Baseflow alsotrended upward at the Fox River and Poplar Creek streamgaging sites. Regional municipal water use from the sand and gravel aquifer decreased from 16 million gallons per day in 2005 to around 13 million gallons per day in 2018. The increase in water levels may be due to a combination of less municipal water use, above average precipitation, and improved household water use efficiency. Because of the projected increases in precipitation intensity, flooding events, and climate variability, we recommend the continuation of BACOG’s groundwater monitoring program to understand long-term (decadal) trends in groundwater levels to support long-term regional planning of water supplies. Because of the predominance of private wells in the region and that a significant portion of the aquifer is susceptible to contamination, we also recommend that groundwater quality sampling be a focus of future BACOG studies.published or submitted for publicationis peer reviewedOpe

Assessing the potential of autonomous submarine gliders for ecosystem monitoring across multiple trophic levels (plankton to cetaceans) and pollutants in shallow shelf seas

A combination of scientific, economic, technological and policy drivers is behind a recent upsurge in the use of marine autonomous systems (and accompanying miniaturized sensors) for environmental mapping and monitoring. Increased spatial–temporal resolution and coverage of data, at reduced cost, is particularly vital for effective spatial management of highly dynamic and heterogeneous shelf environments. This proof-of-concept study involves integration of a novel combination of sensors onto buoyancy-driven submarine gliders, in order to assess their suitability for ecosystem monitoring in shelf waters at a variety of trophic levels. Two shallow-water Slocum gliders were equipped with CTD and fluorometer to measure physical properties and chlorophyll, respectively. One glider was also equipped with a single-frequency echosounder to collect information on zooplankton and fish distribution. The other glider carried a Passive Acoustic Monitoring system to detect and record cetacean vocalizations, and a passive sampler to detect chemical contaminants in the water column. The two gliders were deployed together off southwest UK in autumn 2013, and targeted a known tidal-mixing front west of the Isles of Scilly. The gliders’ mission took about 40 days, with each glider travelling distances of >1000 km and undertaking >2500 dives to depths of up to 100 m. Controlling glider flight and alignment of the two glider trajectories proved to be particularly challenging due to strong tidal flows. However, the gliders continued to collect data in poor weather when an accompanying research vessel was unable to operate. In addition, all glider sensors generated useful data, with particularly interesting initial results relating to subsurface chlorophyll maxima and numerous fish/cetacean detections within the water column. The broader implications of this study for marine ecosystem monitoring with submarine gliders are discussed

The importance of ship log data: reconstructing North Atlantic, European and Mediterranean sea level pressure fields back to 1750

Local to regional climate anomalies are to a large extent determined by the state of the atmospheric circulation. The knowledge of large-scale sea level pressure (SLP) variations in former times is therefore crucial when addressing past climate changes across Europe and the Mediterranean. However, currently available SLP reconstructions lack data from the ocean, particularly in the pre-1850 period. Here we present a new statistically-derived 5°×5° resolved gridded seasonal SLP dataset covering the eastern North Atlantic, Europe and the Mediterranean area (40°W-50°E; 20°N-70°N) back to 1750 using terrestrial instrumental pressure series and marine wind information from ship logbooks. For the period 1750-1850, the new SLP reconstruction provides a more accurate representation of the strength of the winter westerlies as well as the location and variability of the Azores High than currently available multiproxy pressure field reconstructions. These findings strongly support the potential of ship logbooks as an important source to determine past circulation variations especially for the pre-1850 period. This new dataset can be further used for dynamical studies relating large-scale atmospheric circulation to temperature and precipitation variability over the Mediterranean and Eurasia, for the comparison with outputs from GCMs as well as for detection and attribution studie

Common sleep disorders in pregnancy: a review

In this review, we provide a comprehensive overview of common sleep disorders during pregnancy, including their characterization, prevalence, risk factors, and possible contribution to maternal and fetal outcomes. We conducted a quasi-systematic literature search of the MEDLINE database and identified 744 studies from 1991 through 2021, inclusive, that met our inclusion criteria. We synthesized the existing literature on sleep disorders during pregnancy and highlighted controversies, research gaps, and needed clinical developments. Our review covers a range of sleep disorders, including insomnia, obstructive sleep apnea, restless legs syndrome, and circadian rhythm disorders. We discuss the prevalence of these disorders in pregnancy and their potential impact on maternal and fetal health outcomes. We also explore the relationship between sleep disorders, pre-pregnancy comorbidities such as obesity, and pregnancy-related conditions such as gestational diabetes mellitus and preeclampsia. In addition to summarizing the existing literature on sleep disorders during pregnancy, we also highlight opportunities for further research in this area. We suggest that future studies should strive to employ validated and objective measurement tools for sleep disorders and prioritize utilization of longitudinal methods with participant follow-up through postpartum, mid-life, menopause, and beyond. We also put forward investigation into the impact of circadian rhythm disruption on reproductive physiology and early pregnancy outcomes as an area of important work. Overall, our review provides valuable insights on sleep and reproduction and into common sleep disorders during pregnancy and their potential impact on maternal and fetal health outcomes

Mixture modeling with applications in schizophrenia research

Finite mixture modeling, together with the EM algorithm, have been widely used in clustering analysis. Under such methods, the unknown group membership is usually treated as missing data. When the "complete data" (log-)likelihood function does not have an explicit solution, the simplicity of the EM algorithm breaks down. Authors, including Rai and Matthews (1993), Lange (1995a) and Titterington (1984), developed modified algorithms therefore. As motivated by research in a large neurobiological project, we propose in this paper a new variant of such modifications and show that it is self-consistent. Moreover, simulations are conducted to demonstrate that the new variant converges faster than its predecessors. Originally published Computational Statistics and Data Analysis, Vol. 53, No. 7, May 200

Visual Tuning Properties of Genetically Identified Layer 2/3 Neuronal Types in the Primary Visual Cortex of Cre-Transgenic Mice

The putative excitatory and inhibitory cell classes within the mouse primary visual cortex V1 have different functional properties as studied using recording microelectrode. Excitatory neurons show high selectivity for the orientation angle of moving gratings while the putative inhibitory neurons show poor selectivity. However, the study of selectivity of the genetically identified interneurons and their subtypes remain controversial. Here we use novel Cre-driver and reporter mice to identify genetic subpopulations in vivo for two-photon calcium dye imaging: Wfs1(+)/Gad1(−) mice that labels layer 2/3 excitatory cell population and Pvalb(+)/Gad1(+) mice that labels a genetic subpopulation of inhibitory neurons. The cells in both mice were identically labeled with a tdTomato protein, visible in vivo, using a Cre-reporter line. We found that the Wfs1(+) cells exhibited visual tuning properties comparable to the excitatory population, i.e., high selectivity and tuning to the angle, direction, and spatial frequency of oriented moving gratings. The functional tuning of Pvalb(+) neurons was consistent with previously reported narrow-spiking interneurons in microelectrode studies, exhibiting poorer selectivity than the excitatory neurons. This study demonstrates the utility of Cre-transgenic mouse technology in selective targeting of subpopulations of neurons and makes them amenable to structural, functional, and connectivity studies

Overview of CFD Validation Experiments for Circulation Control Applications at NASA

Circulation control is a viable active flow control approach that can be used to meet the NASA Subsonic Fixed Wing project s Cruise Efficient Short Take Off and Landing goals. Currently, circulation control systems are primarily designed using empirical methods. However, large uncertainty in our ability to predict circulation control performance has led to the development of advanced CFD methods. This paper provides an overview of a systematic approach to developing CFD tools for basic and advanced circulation control applications. This four-step approach includes "Unit", "Benchmar", "Subsystem", and "Complete System" experiments. The paper emphasizes the ongoing and planned 2-D and 3-D physics orientated experiments with corresponding CFD efforts. Sample data are used to highlight the challenges involved in conducting circulation control computations and experiments