11,066 research outputs found
Robotic and automatic welding development at the Marshall Space Flight Center
Welding automation is the key to two major development programs to improve quality and reduce the cost of manufacturing space hardware currently undertaken by the Materials and Processes Laboratory of the NASA Marshall Space Flight Center. Variable polarity plasma arc welding has demonstrated its effectiveness on class 1 aluminum welding in external tank production. More than three miles of welds were completed without an internal defect. Much of this success can be credited to automation developments which stabilize the process. Robotic manipulation technology is under development for automation of welds on the Space Shuttle's main engines utilizing pathfinder systems in development of tooling and sensors for the production applications. The overall approach to welding automation development undertaken is outlined. Advanced sensors and control systems methodologies are described that combine to make aerospace quality welds with a minimum of dependence on operator skill
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Facing up to the challenge of behavioural observation in infant hearing assessment
The ability to assess detection and discrimination of speech by infants has proved elusive. Dr Iain Jackson and colleagues discuss how new technologies and fresh approaches might offer valuable insight into young infants’ behavioural responses to sound
Deducing radiation pressure on a submerged mirror from the Doppler shift
Radiation pressure on a flat mirror submerged in a transparent liquid,
depends not only on the refractive index n of the liquid, but also on the phase
angle psi_0 of the Fresnel reflection coefficient of the mirror, which could be
anywhere between 0^{\circ} and 180^{\circ}. Depending on the value of psi_0,
the momentum per incident photon picked up by the mirror covers the range
between the Abraham and Minkowski values, i.e., the interval
(2\hbarw_0/nc,2n\hbarw_0/c). Here \hbar is the reduced Planck constant, w_0 is
the frequency of the incident photon, and c is the speed of light in vacuum. We
argue that a simple experimental setup involving a dielectric slab of
refractive index n, a vibrating mirror placed a short distance behind the slab,
a collimated, monochromatic light beam illuminating the mirror through the
slab, and an interferometer to measure the phase of the reflected beam, is all
that is needed to deduce the precise magnitude of the radiation pressure on a
submerged mirror. In the proposed experiment, the transparent slab plays the
role of the submerging liquid (even though it remains detached from the mirror
at all times), and the adjustable gap between the mirror and the slab simulates
the variable phase-angle psi_0. The phase of the reflected beam, measured as a
function of time during one oscillation period of the mirror, then provides the
information needed to determine the gap-dependence of the reflected beam's
Doppler shift and, consequently, the radiation pressure experienced by the
mirror.Comment: 9 pages, 2 figures, 13 equation
Chronicity and Mental Health Service Utilization for Anxiety, Mood, and Substance Use Disorders among Black Men in the United States; Ethnicity and Nativity Differences.
This study investigated ethnic and nativity differences in the chronicity and treatment of psychiatric disorders of African American and Caribbean Black men in the U.S. Data were analyzed from the National Survey of American Life, a population-based study which included 1859 self-identified Black men (1222 African American, 176 Caribbean Black men born within the U.S., and 461 Caribbean Black men born outside the U.S.). Lifetime and twelve-month prevalence of DSM-IV mood, anxiety, and substance use disorders (including Bipolar I and Dysthmia), disorder chronicity, and rate of mental health services use among those meeting criteria for a lifetime psychiatric disorder were examined. Logistic regression models were employed to determine ethnic differences in chronicity, and treatment utilization for disorders. While rates of DSM-IV disorders were generally low in this community sample of Black men, their disorders were chronic and remained untreated. Caribbean Black men born in the U.S. had higher prevalence of Post-Traumatic Stress Disorder, Major Depressive Disorder, and Alcohol Abuse Disorder compared with African American men. Foreign born Caribbean Black men experienced greater chronicity in Social Phobia and Generalized Anxiety Disorder compared to other Black Men. Utilization of mental health service was low for all groups of Black Men, but lowest for the foreign born Caribbean Black men. Results underscore the large unmet needs of both African American and Caribbean Black men in the United States. Results also highlight the role of ethnicity and nativity in mental disorder chronicity and mental health service utilization patterns of Black men
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HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs.
Maintenance of high-turnover tissues such as the epidermis requires a balance between stem cell proliferation and differentiation. The molecular mechanisms governing this process are an area of investigation. Here we show that HNRNPK, a multifunctional protein, is necessary to prevent premature differentiation and sustains the proliferative capacity of epidermal stem and progenitor cells. To prevent premature differentiation of progenitor cells, HNRNPK is necessary for DDX6 to bind a subset of mRNAs that code for transcription factors that promote differentiation. Upon binding, these mRNAs such as GRHL3, KLF4, and ZNF750 are degraded through the mRNA degradation pathway, which prevents premature differentiation. To sustain the proliferative capacity of the epidermis, HNRNPK is necessary for RNA Polymerase II binding to proliferation/self-renewal genes such as MYC, CYR61, FGFBP1, EGFR, and cyclins to promote their expression. Our study establishes a prominent role for HNRNPK in maintaining adult tissue self-renewal through both transcriptional and post-transcriptional mechanisms
Deformed quantum mechanics and q-Hermitian operators
Starting on the basis of the non-commutative q-differential calculus, we
introduce a generalized q-deformed Schr\"odinger equation. It can be viewed as
the quantum stochastic counterpart of a generalized classical kinetic equation,
which reproduces at the equilibrium the well-known q-deformed exponential
stationary distribution. In this framework, q-deformed adjoint of an operator
and q-hermitian operator properties occur in a natural way in order to satisfy
the basic quantum mechanics assumptions.Comment: 10 page
Gravitational Wave Bursts from Cosmic Superstring Reconnections
We compute the gravitational waveform produced by cosmic superstring
reconnections. This is done by first constructing the superstring reconnection
trajectory, which closely resembles that of classical, instantaneous
reconnection but with the singularities smoothed out due to the string path
integral. We then evaluate the graviton vertex operator in this background to
obtain the burst amplitude. The result is compared to the detection threshold
for current and future gravitational wave detectors, finding that neither
bursts nor the stochastic background would be detectable by Advanced LIGO. This
disappointing but anticipated conclusion holds even for the most optimistic
values of the reconnection probability and loop sizes.Comment: 26 pages, 6 figures; v2: references added and typos correcte
<i>‘What retention’ means to me</i>: the position of the adult learner in student retention
Studies of student retention and progression overwhelmingly appear adopt definitions that place the institution, rather than the student, at the centre. Retention is most often conceived in terms of linear and continuous progress between institutionally identified start and end points.
This paper reports on research that considered data from 38 in-depth interviews conducted with individuals who had characteristics often associated with non-traditional engagement in higher education who between 2006 and 2010 had studied an ‘Introduction to HE’ module at one distance higher education institution, some of whom had progressed to further study at that institution, some of whom had not. The research deployed a life histories approach to seek a finer grained understanding of how individuals conceptualise their own learning journey and experience, in order to reflect on institutional conceptions of student retention.
The findings highlight potential anomalies hidden within institutional retention rates – large proportions of the interview participants who were not ‘retained’ by the institution reported successful progression to and in other learning institutions and environments, both formal and informal. Nearly all described positive perspectives on lifelong learning which were either engendered or improved by the learning undertaken. This attests to the complexity of individuals’ lives and provides clear evidence that institution-centric definitions of retention and progression are insufficient to create truly meaningful understanding of successful individual learning journeys and experiences. It is argued that only through careful consideration of the lived experience of students and a re-conception of measures of retention, will we be able to offer real insight into improving student retention
Acidification effects on biofouling communities: winners and losers
How ocean acidification affects marine life is a major concern for science and society. However, its impacts on encrusting biofouling communities, that are both the initial colonizers of hard substrata and of great economic importance, are almost unknown. We showed that community composition changed significantly, from 92% spirorbids, 3% ascidians and 4% sponges initially to 47% spirorbids, 23% ascidians and 29% sponges after 100days in acidified conditions (pH 7.7). In low pH, numbers of the spirorbid Neodexiospira pseudocorrugata were reduced x5 compared to controls. The two ascidians present behaved differently with Aplidium sp. decreasing x10 in pH 7.7, whereas Molgula sp. numbers were x4 higher in low pH than controls. Calcareous sponge (Leucosolenia sp.) numbers increased x2.5 in pH 7.7 over controls. The diatom and filamentous algal community was also more poorly developed in the low pH treatments compared to controls. Colonization of new surfaces likewise showed large decreases in spirorbid numbers, but numbers of sponges and Molgula sp. increased. Spirorbid losses appeared due to both recruitment failure and loss of existing tubes. Spirorbid tubes are comprised of a loose prismatic fabric of calcite crystals. Loss of tube materials appeared due to changes in the binding matrix and not crystal dissolution, as SEM analyses showed crystal surfaces were not pitted or dissolved in low pH conditions. Biofouling communities face dramatic future changes with reductions in groups with hard exposed exoskeletons and domination by soft-bodied ascidians and sponges.EU [227799, 00415/2010]; Natural Environment Research Council [bas0100036, bas0100025
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