Bifurcations and bistability in cavity assisted photoassociation of Bose-Einstein condensed molecules

We study the photo-association of Bose-Einstein condensed atoms into molecules using an optical cavity field. The driven cavity field introduces a new dynamical degree of freedom into the photoassociation process, whose role in determining the stationary behavior has not previously been considered. The semiclassical stationary solutions for the atom and molecules as well as the intracavity field are found and their stability and scaling properties are determined in terms of experimentally controllable parameters including driving amplitude of the cavity and the nonlinear interactions between atoms and molecules. For weak cavity driving, we find a bifurcation in the atom and molecule number occurs that signals a transition from a stable steady state to nonlinear Rabi oscillations. For a strongly driven cavity, there exists bistability in the atom and molecule number

Redesigning and teaching veterinary microbiology laboratory exercises with combined on-site and online participation during the COVID-19 pandemic

The COVID-19 (coronavirus disease 2019) pandemic has forced universities to find new ways to conduct learning and teaching, as traditional face-to-face teaching has been prevented or restricted to an absolute minimum in many instances. Therefore, we redesigned and taught second-year veterinary student microbiology laboratory exercises (labs) with a hybrid learning approach. For this, a novel 'remote partner' model was implemented in which students present on-site in the laboratory worked synchronously pairwise with their remote partner present online. A student feedback survey revealed that in this remote partner model, both on-site and online participation in the labs were experienced as being useful in improving their laboratory skills. The students' overall performance in hands-on microbiological laboratory skills and safe working practices was similar in the hybrid learning approach (the 2021 class) and in the traditional on-site participation approach (the 2018-20 classes). This study suggests that the remote partner model is an effective way to acquire microbiological laboratory skills. This learning approach can be used in the non-pandemic future and/or also be applied to other fields.Microbiological laboratory skills can be developed using a hybrid model combining synchronous on-site and online learning for students working in pairs.Peer reviewe

Nonlocal Multiscale Single Image Statistics From Sentinel-1 SAR Data for High Resolution Bitemporal Forest Wind Damage Detection

Change detection of synthetic aperture radar (SAR) data is a challenge for high-resolution applications. This study presents a new nonlocal averaging approach (STAl'SAR) to reduce the speckle of single Sentinel-1 SAR images and statistical parameters derived from the image. The similarity of SAR pixels is based on the statistics of 3 x 3 window as represented by the mean, standard deviation, median, minimum, and maximum. K-means clustering is used to divide the SAR image in 30 similarity clusters. The nonlocal averaging is carried out within each cluster separately in magnitude order of the 3 x 3 window averages. The nonlocal filtering is applicable not only to the original pixel backscattering values but also to statistical parameters, such as standard deviation. The statistical parameters to be filtered can represent any window size, according to the need of the application. The nonlocally averaged standard deviation derived in two spatial resolutions, 3 x 3 and 7 x 7 windows, are demonstrated here for improving the resolution in which the forest damages can be detected using the VH polarized backscattering spatial variation change.Peer reviewe

Brain mechanisms underlying cue-based memorizing during free viewing of movie Memento

How does the human brain recall and connect relevant memories with unfolding events? To study this, we presented 25 healthy subjects, during functional magnetic resonance imaging, the movie 'Memento' (director C. Nolan). In this movie, scenes are presented in chronologically reverse order with certain scenes briefly overlapping previously presented scenes. Such overlapping "key-frames" serve as effective memory cues for the viewers, prompting recall of relevant memories of the previously seen scene and connecting them with the concurrent scene. We hypothesized that these repeating key-frames serve as immediate recall cues and would facilitate reconstruction of the story piece-by-piece. The chronological version of Memento, shown in a separate experiment for another group of subjects, served as a control condition. Using multivariate event-related pattern analysis method and representational similarity analysis, focal fingerprint patterns of hemodynamic activity were found to emerge during presentation of key-frame scenes. This effect was present in higher-order cortical network with regions including precuneus, angular gyrus, cingulate gyrus, as well as lateral, superior, and middle frontal gyri within frontal poles. This network was right hemispheric dominant. These distributed patterns of brain activity appear to underlie ability to recall relevant memories and connect them with ongoing events, i.e., "what goes with what" in a complex story. Given the real-life likeness of cinematic experience, these results provide new insight into how the human brain recalls, given proper cues, relevant memories to facilitate understanding and prediction of everyday life events.Peer reviewe

Fatal Tick-Borne Encephalitis Virus Infections Caused by Siberian and European Subtypes, Finland, 2015

In most locations except for Russia, tick-borne encephalitis is mainly caused by the European virus subtype. In 2015, fatal infections caused by European and Siberian tick-borne encephalitis virus subtypes in the same Ixodes ricinus tick focus in Finland raised concern over further spread of the Siberian subtype among widespread tick species.Peer reviewe

On-chip Phase Locked Loop (PLL) design for clock multiplier in CMOS Monolithic Active Pixel Sensors (MAPS)

In a detector system, clock distribution to sensors must be controlled at a level allowing proper synchronisation. In order to reach theses requirements for the HFT (Heavy Flavor Tracker) upgrade at STAR (Solenoidal Tracker at RHIC), we have proposed to distribute a low frequency clock at 10 MHz which will be multiplied to 160 MHz in each sensor by a PLL. A PLL has been designed for period jitter less than 20 ps rms, low power consumption and manufactured in a 0.35 μm CMOS process

Lipreading and Covert Speech Production Similarly Modulate Human Auditory-Cortex Responses to Pure Tones

Watching the lips of a speaker enhances speech perception. At the same time, the 100 ms response to speech sounds is suppressed in the observer's auditory cortex. Here, we used whole-scalp 306-channel magnetoencephalography (MEG) to study whether lipreading modulates human auditory processing already at the level of the most elementary sound features, i.e., pure tones. We further envisioned the temporal dynamics of the suppression to tell whether the effect is driven by top-down influences. Nineteen subjects were presented with 50 ms tones spanning six octaves (125–8000 Hz) (1) during “lipreading,” i.e., when they watched video clips of silent articulations of Finnish vowels /a/, /i/, /o/, and /y/, and reacted to vowels presented twice in a row; (2) during a visual control task; (3) during a still-face passive control condition; and (4) in a separate experiment with a subset of nine subjects, during covert production of the same vowels. Auditory-cortex 100 ms responses (N100m) were equally suppressed in the lipreading and covert-speech-production tasks compared with the visual control and baseline tasks; the effects involved all frequencies and were most prominent in the left hemisphere. Responses to tones presented at different times with respect to the onset of the visual articulation showed significantly increased N100m suppression immediately after the articulatory gesture. These findings suggest that the lipreading-related suppression in the auditory cortex is caused by top-down influences, possibly by an efference copy from the speech-production system, generated during both own speech and lipreading.Peer reviewe

Marination increased tyramine levels in rainbow trout fillet strips packaged under modified atmosphere

Marinades are increasingly used to manufacture raw fish products. In corresponding meats, marinating is known to have a major effect on the composition of the microbiome, but the effect of marinating on fish is not known as well. This knowledge gap prompted our study of the microbial ecology and amine formation in marinated and unmarinated modified atmosphere commercially packaged rainbow trout fillet strips. According to our findings, marination increased the maximum concentrations (7-8 log CFU/g) of psychrotrophic bacteria by one loga-rithmic unit and led to 5 times higher average tyramine concentrations than the corresponding unmarinated product. Instead, trimethylamine concentrations were 30 times higher in the unmarinated product than those in the marinated one. According to the 16 S rRNA sequence analyses, lactic acid bacteria (LAB) predominated in the marinated strips one day after the use-by date, whereas in the unmarinated strips Fusobacteriaceae and LAB were the dominating taxa. Based on the culture-dependent analysis, Latilactobacillus fuchuensis was the prevailing LAB in both products. Since the subset of L. fuchuensis strains tested was able to produce tyramine in vitro, we hypothesise that the use of the acidic marinade activated the production of tyrosine-decarboxylating enzymes in L. fuchuensis and led to the increased tyramine concentrations.Peer reviewe

Cancer Patients' Symptom Burden and Health-related Quality of Life (HRQoL) at Tertiary Cancer Center from 2006 to 2013 : A Cross-sectional Study

Background/Aim: To observe changes in symptoms and health-related quality of life (HRQoL) over 7 years among cancer patients at different stages of the disease. Patients and Methods: This prospective cross-sectional study at the Helsinki University Hospital Cancer Center, was carried out in 2006 and repeated in 2013. All participants filled in the EORTC-QLQ-C30 questionnaire. Results: Altogether, 581 patients responded (49% in 2006 and 54% in 2013). The disease was local in 51% and advanced in 49% of patients. The HRQoL was significantly lower, except for emotional and cognitive functions, and the symptom burden more severe in advanced cancer. The most prevalent symptoms were fatigue (93% and 85%; moderate/severe 22% and 9%), pain (65% and 47%; moderate/severe 16% and 5%), and insomnia (64% and 60%; moderate/severe 20 and 21%), respectively. No changes in HRQoL or symptoms were found at 7 years. Conclusion: There is a need for early integrated palliative care to improve HRQoL during cancer treatments.Peer reviewe