A review of research on the growth of multinational enterprises: a Penrosean lens

We provide a comprehensive review of the growth of multinational enterprises (MNEs) based on a quarter-century (25 years) of scholarly international business publications. We synthesize research insights on the determinants of the growth of MNEs through the lens of Penrose’s theory of firm growth, which is the most influential theoretical perspective on firm growth. The review takes stock of the research findings on the facilitators, constraints, and the trajectory of growth of MNEs, and elaborates on the commonalities and differences between research on the growth of MNEs that draws on Penrose’s theory and research that does not. This comparison highlights the opportunity to build an internally coherent theory of the growth of MNEs, that is, a theory that connects ‘what an MNE is’ to ‘what determines an MNE’s growth.’ It also indicates that past research placed a strong emphasis on exogenous factors (e.g., cross-country distances) as key constraints on growth even though the Penrosean lens suggests a close consideration of endogenous factors that drive international growth, as well as endogenizing the ostensibly exogenous growth determinants. The review highlights the importance of firm-specific managerial knowledge and learning, which shapes the direction of the growth of MNEs and ensures its administrative coherence

Penrose's The Theory of the Growth of the Firm: an exemplar of engaged scholarship

Edith Penrose's (1959) classic book, The Theory of the Growth of the Firm, made a substantial impact on strategic management research, especially in the context of the resource-based view of the firm, and the ripple effects of her impact continue to unfold today in various disciplines. The book serves as a remarkably rich source of inspiration for scholarly research and a generative source of ideas, which are waiting to be further developed. In this paper, we examine Penrose's (1959) classic and provide: (1) the process by which this book came about; (2) a summary of its key ideas; (3) the subsequent impact of the book, in which we focus on mathematical models; and (4) a discussion of some of the research lessons learned from this exemplar of engaged scholarship. We invite management science and operations scholars to discover the rich scientific world of Edith Penrose and experience the product and process of her research creativit

Suicide among the American Indians; two workshops: Aberdeen, South Dakota, September 1967; Lewistown, Montana, November 1967.

This publication contains seven workshop papers discussing suicide and American Indians in South Dakota and Montana

Digital Transformation Business Landscape

Chapter 3 is based on an approach to the background and basic understanding of digital transformation; its benefits, the two perspectives of digital transformation, the four dimensions of digital transformation strategies and the procedural aspects of digital transformation strategies are discussed. Following that, there is an explanation on how to integrate digital transformation into firms and some challenges and strategic paths in order to do this effectively.2019-2

Photoswitchable diacylglycerols enable optical control of protein kinase C.

Increased levels of the second messenger lipid diacylglycerol (DAG) induce downstream signaling events including the translocation of C1-domain-containing proteins toward the plasma membrane. Here, we introduce three light-sensitive DAGs, termed PhoDAGs, which feature a photoswitchable acyl chain. The PhoDAGs are inactive in the dark and promote the translocation of proteins that feature C1 domains toward the plasma membrane upon a flash of UV-A light. This effect is quickly reversed after the termination of photostimulation or by irradiation with blue light, permitting the generation of oscillation patterns. Both protein kinase C and Munc13 can thus be put under optical control. PhoDAGs control vesicle release in excitable cells, such as mouse pancreatic islets and hippocampal neurons, and modulate synaptic transmission in Caenorhabditis elegans. As such, the PhoDAGs afford an unprecedented degree of spatiotemporal control and are broadly applicable tools to study DAG signaling

Don't lose sight of the importance of the individual in effective falls prevention interventions

Falls remain a major public health problem, despite strong growth in the research evidence of effective single and multifactorial interventions, particularly in the community setting. A number of aspects of falls prevention require individual tailoring, despite limitations being reported regarding some of these, including questions being raised regarding the role of falls risk screening and falls risk assessment. Being able to personalise an individual's specific risk and risk factors, increase their understanding of what interventions are likely to be effective, and exploring options of choice and preference, can all impact upon whether or not an individual undertakes and sustains participation in one or more recommendations, which will ultimately influence outcomes. On all of these fronts, the individual patient receiving appropriate and targeted interventions that are meaningful, feasible and that they are motivated to implement, remains central to effective translation of falls prevention research evidence into practice

An unusual presentation of Castleman's Disease:a case report

BACKGROUND: Castleman's disease (CD), a rare condition of uncertain etiology, involves a massive proliferation of lymphoid tissues and typically presents as mediastinal masses. We describe a patient with CD who presented with diffuse adenopathy involving the inguinal, paratracheal, retroperitoneal, axillary, and pelvic regions. CASE PRESENTATION: Case report describing presentation, work-up, management and clinical course of a patient with Castleman's disease in the setting of a county hospital in metropolitan area. Patient was treated with chemotherapeutic agents. CONCLUSIONS: To our knowledge, this represents the first case of CD involving an HIV-positive patient with a negative Human Herpes Virus (HHV-8) viral panel. Because patients with similar clinical histories are at high risk for the development of non-Hodgkin's lymphoma and Kaposi sarcoma, regular medical surveillance is recommended