Perilaku Seksual Pranikah pada Mahasiswa

Meningkatnya perilaku seksual pranikah berdampak pada kehamilan di luar nikah. Masalahpenelitian adalah faktor apakah yang berhubungan dengan perilaku seksual pranikahmahasiswa siswa di STIKes Medistra Indonesia Jakarta pada tahun 2011. Tujuan penelitianuntuk melihat pengaruh faktor predisposisi (karakter, konsep diri, pengetahuan, sikap, danreligiusitas), faktor reinforcing (peran teman sebaya, peran keluarga dan sikap PA dalamsiswa mentoring pribadi tentang kesehatan reproduksi remaja) dan faktor pemungkin(tinggal siswa) perilaku seksual pranikah mahasiswa. Metode penelitian kuantitatif dengandesain cross sectional. Subyek penelitian adalah siswa berusia ≤ 24 tahun dan belum menikahdi STIKes Medistra Indonesia Jakarta pada tahun 2011, berjumlah 582 responden. Tekniktotal sampling menggunakan analisis korelasi dan regresi dengan α = 0,05. Hasil penelitianmenunjukkan ada tiga variabel dalam faktor predisposisi memiliki pengaruh yang signifi kanterhadap perilaku seksual pranikah siswa yaitu karakter, konsep diri dan sikap. Kekuatankarakter 2%, konsep diri 2%, dan sikap 15% terhadap perilaku seksual pranikah siswa.Simpulan penelitian, faktor yang mempengaruhi perilaku seksual pranikah siswa di STIKesMedistra Indonesia termasuk karakter, konsep diri dan sikap. The increasing premarital sexual behavior impact on pregnancy outside marriage. Researchproblem was whether factors associated with premarital sexual behavior of college studentsSTIKes Medistra Indonesian in Jakarta in 2011. Research purpose to know the eff ect ofpredisposing factors (personality, self-concept, knowledge, attitudes, and religiosity), reinforcingfactors (the role of peers, family roles, and attitudes of students' teacher to personal mentoringon adolescent reproductive health) and enabling factors (student residence) behavior premaritalsexual students. Quantitative research methods with cross sectional design. Subjects were studentsaged ≤ 24 years old and not married in STIKes Medistra Indonesia Jakarta in 2011, totaling 582respondents. Total sampling technique using correlation and regression analysis with α=0.05.Th e results showed there were three variables in predisposing factors have a signifi cant infl uenceon premarital sexual behavior of students that character, self-concept, and attitude. 2% strengthcharacter, 2% self-concept, and 15% attitude toward students premarital sexual behavior. Th econclusions, the factors aff ecting premarital sexual behavior of students were character, selfconcept,and attitude

Ocimum Basilicum as Alternative Natural Cancer Care

Cancer is the most dreadful disease worldwide in terms of morbidity and mortality. The exact cause of cancer development and progression is not fully known. Ocimum Basilicum (OB) or basil contains citric acid, essential oils, 1-8 sineol, arigin, anetol, flavonoid, boron, stigmasterol, eugenol, beta-carotene, magnesium and tryptophan. Works as an anticancer through phenolic compounds (caffeine acid, p-kumarat acid) which is an antiproliferative agent, which will increase the number of non-apoptotic cells in the synthesis phase in the cell cycle and decrease the number of non-apoptotic cells in the G2/M phase. While caffeine acid may cause an increase in FasL, which is a receptor of death (Fas). The existence of a complex between FasL and Fas can induce signaling that induces cell death. Phenolics have also been shown to decrease the Bcl2 antiapoptotic protein, so apoptosis does not work. Increased Bcl2 expression will be followed by an increase in Bax, which is produced because cancer cells may mutate in the p53 protein, triggering a dimer between the two and triggering apoptosis through Fas. OB extract, containing flavonoids that have an effect as a chemopreventive agent by protecting lymphocytes from cancer induction. Another compound is the essential oil (terpenoid) that can inhibit tumor by improving the performance of Human Natural Killer in immune system (immunostimulan), so as to destroy tumor cells and increase macrophage cells that act as the phagocytes of damaged cells. In this review will be discussed about the role of OB in the natural treatment of cancer and the working mechanisms involved in it

A MINI REVIEW OF INDONESIAN MEDICINAL PLANTS FOR VULVOVAGINAL CANDIDIASIS

Vulvovaginal candidiasis (VVC) is the second normal of vaginal mucosal infection after bacterial that influencing right around 70%-75% of women once in a lifetime. Azoles antibiotics are used in treatment for VVC but limited because cause drug resistance in patients. Therefore, today need for new antifungal agents for Candida albicans infection that safe and without side effect. This article reviews Indonesian medicinal plants related to the antifungal activity and mechanisms of action against C. albicans. The searches for this review were conducted via the databases PubMed, Google Scholar, online Science Direct, Science and Technology Index. The document relevant analyzed and included in the study. Almost 34 medicinal plants used for anti-Candida in Indonesia were reported. About 5.88% and 94.12% of Indonesian medicinal plants were significant and weak as an anti-Candida activity, respectively. The plants with the greatest anti-Candida activity were Curcuma xanthorrhiza and Syzygium aromaticum. The anti-Candida action involved disruption of hyphae production, membrane permeabilization, cell wall, biofilm formation, envelope, and filament formation. These results contribute to the drug discovering of the anti-Candida from Indonesian medicinal plants

Analysis Concentration of Toxoplasma gondii on Anti-Toxoplasma IgG-IgM Antibody Levels, and the Outcomes of Pregnancy in Mice Balb/c

Introduction: Toxoplasma gondii is an obligate intracellular protozoan para-site that can infect any warm blood vertebrae, and if first trimester pregnant woman infected, it may cause abortion. The objective is to prove the effect of the Toxoplasma gondii concentration in anti-toxoplasma IgG-IgM antibody levels, and the outcomes of Balb/c mice pregnancies. Materials and Methods: The study was conducted in Balb/c mice with inclusion criteria, and was con-ditioned pregnant. The pathogen strains of Toxoplasma gondii tachyzoite in-jected intraperitoneally. The blood samples were taken serially to be tested for anti-toxoplasma IgG-IgM antibody levels. After the mice were injected with tachyzoite, they are assessed every day to observe their body weight, vaginal bleeding, and labor. Anti-toxoplasma IgG-IgM antibody levels examined us-ing qualitative mouse IgG-IgM antibody ELISA KIT. Results: Anti-toxoplasma IgM antibody levels increased significantly after 24 hours of injection tachy-zoites in all dose groups, and remained high through day 21. Anti-toxoplasma antibody IgG levels increased significantly after 72 hours post injection and remained elevated until day 21. The incidence of abortion is 100% in mice which injected tachyzoite levels 1 × 103 and 1 × 104, and the incidence of abor-tion approximately 2 - 4 days post injection. 100% of mice that were injected with tachyzoites 1 × 101 and 1 × 102 have labor at term. Physical anomaly was found in baby mice from mice that were injected with tachyzoite 1 × 102. Conclusion: There is a significant correlation between the concentrations of Toxoplasma gondii tachyzoite with anti-toxoplasma IgG-IgM antibody levels

Animal Modeling Try Strain Balb/c Mice With Gardnerella Vaginalis

Gardnerella vaginalis is the causative agent of sexually transmitted infections (STIs) of the bacterial class and is the main species of bacterial vaginosis (BV), classified as gram-negative bacteria, and is anaerobic facultative. The incidence of bacterial vaginosis increased rapidly in Indonesia with a prevalence of approximately 20-30% of women of childbearing age suffering from sexually transmitted infections diagnosed BV and an increase of 50-60%. BV is the leading cause of vaginal infection in women of childbearing age and is one of the most common infectious diseases in the gynecological obstetrics. Balb-C is a trying animal with a human-like cervical vagina. Objective: To identify the dose of Gardnerella vaginalis bacteria that has the potential to live on the vagina of experimental animals. Methods: Balb/c female strain, adult age 8-12 weeks, weight 20-25 g. Using the patient's urine specimen suspect Bacterial vaginosis was inoculated on intravaginal Balb-c each of 10 ?l doses of 3 x 106, 3 x 105, and 3 x 104. Prior to inoculation (H0), a vaginal swab was taken and continued at H

The Role of FSH, LH, Estradiol and Progesterone Hormone on Estrus Cycle of Female Rats

The estrous cycle is a recurrent process that describes changes in reproductive hormone levels caused by ovarian activity under the influence of pituitary hormones. Estrous cycles are characterized by morphological changes in ovaries, the uterus and the vaginal cells. The length of the estrous cycle and the frequency of the reproductive cycle in each organism are different. In mice, lasts for about 4-5 days. The estrus cycle consists of four phases, namely proestrus, estrus, metestrus and diestrus. During this period, the vaginal mucosa undergoes tremendous structural change

Postpartum Anxiety and Stress during the Covid-19 Pandemic

This study aims to obtain information about the anxiety and stress of postpartum mothers during the COVID-19 pandemic. This study used a descriptive survey method on a sample of pregnant women and women giving birth by purposive sampling, namely those who visited the Independent Practice Midwife (BPM) clinic in Bekasi City from April to July 2020, totaling 78 people. Data were collected using the DASS-21 questionnaire which was packaged in a google form and distributed online via WhatsApp social media. The data collected was then analyzed descriptively to be presented as a result of the research. The results showed that the psychological response to anxiety was normal 50 (64.10%), mild 14 (17.95%), moderate 11 (14.10%), severe 2 (2.56%), and very heavy 1 (1.28 %) of respondents. While the psychological response to normal stress was 59 (75.64%), mild 11 (14.10%), moderate 6 (7.69%), and severe 2 (2.56%) experienced psychologically normal but some experienced anxiety and stress. Most of the psychological responses to normal anxiety, but there are mild, moderate, severe, and very severe anxiety, as well as psychological responses to stress, although most normal, there is also mild, moderate, and severe stress. &nbsp