3,677 research outputs found
Intersections: Diving into the FRA LGBTI II survey data - Lesbians Briefing
Disaggregated data, which can look deeply into the lived experiences of marginalised people, is a key demand of LGBTI and other human rights groups. With this in mind, over the last year ILGA-Europe have been partnering with a variety of NGOs in the region to analyse the FRA 2019 LGBTI Survey II data and pull out experiences of those experiencing intersectional marginalisation. This work is based on analysis co-commissioned by ILGA-Europe and TGEU.Over the coming months, watch this space for in-depth briefings on youth, intersex people, religious and ethnic minorities, older LGBTI people, trans people, and others.This, our briefing on Lesbians was carried out alongside the EuroCentralAsian Lesbian Community EL*C
Models of collaboration between general practice and mental health services in Italy.
Background and objectives: Anxiety and Depressive disorders represent an important public health problem, which involves not only the mental health services, but the General Practice as well. This paper examines models of Collaboration between General Practice and Community Mental Health Services developed in Italy. Methods: Different Consultation -Liaison activities are presented. For every Collaboration model advantages and disadvantage are discussed. Results: The structured Consultation Liaison Service is based on supplying diagnostic consultation and therapeutic interventions in support of General Practitioners (GPs). The service could be based in either a Community Mental Health Centre (CMHC) or externally. Diagnostic evaluation can be followed by brief and focal therapeutic interventions, in support of the GP's therapeutic plan. The spontaneous collaboration in small centres are frequent in rural areas where the contained dimensions of the services and the direct acquaintance between psychiatrists and GPs encourage the personalization of the collaboration. The model of Liaison and Group-Training focuses on direct contact between consultant and GPs. In the course of regular meetings, the consultant gives the GPs supervision and education, and they can discuss the therapeutic plans for patients requiring specialist intervention. Conclusion: The empiric classification presented should be considered an attempt to represent a complex reality. Every service, in fact, carries out activities that are necessarily wider than abstract typologies and that overlap with other models' activities
Defining the Anti-Cancer Activity of Tricarbonyl Rhenium Complexes: Induction of G2/M Cell Cycle Arrest and Blockade of Aurora-A Kinase Phosphorylation
Rhenium and ruthenium complexes containing N-heterocylic carbene (NHC) ligands and conjugated to indomethacin were prepared. The anticancer properties were probed against pancreatic cell lines, revealing a remarkable activity of the rhenium fragment as anticancer agent. The ruthenium complexes were found to be inactive against the same pancreatic cancer cell lines, either alone or in conjugation with indomethacin. An in-depth biological study revealed the origin of the anticancer properties of the rhenium tricarbonyl fragment, of which a complete elucidation had yet to be achieved. It was found that the rhenium complexes induce cell cycle arrest at the G2/M phase by inhibiting the phosphorylation of Aurora-A kinase. A preliminary study on the structure-activity relationship on a large family of these complexes revealed that the anticancer properties are mainly associated with the lability of the ancillary ligand, with inert complexes showing limited to no anticancer properties
Hints for a Turnover at the Snow Line in the Giant Planet Occurrence Rate
The orbital distribution of giant planets is crucial for understanding how
terrestrial planets form and predicting yields of exoplanet surveys. Here, we
derive giant planets occurrence rates as a function of orbital period by taking
into account the detection efficiency of the Kepler and radial velocity (RV)
surveys. The giant planet occurrence rates for Kepler and RV show the same
rising trend with increasing distance from the star. We identify a break in the
RV giant planet distribution between ~2-3 au -- close to the location of the
snow line in the Solar System -- after which the occurrence rate decreases with
distance from the star. Extrapolating a broken power-law distribution to larger
semi-major axes, we find good agreement with the ~ 1% planet occurrence rates
from direct imaging surveys. Assuming a symmetric power law, we also estimate
that the occurrence of giant planets between 0.1-100 au is 26.6 +7.5 -5.4% for
planets with masses 0.1-20MJ and decreases to 6.2 +1.5 -1.2% for planets more
massive than Jupiter. This implies that only a fraction of the structures
detected in disks around young stars can be attributed to giant planets.
Various planet population synthesis models show good agreement with the
observed distribution, and we show how a quantitative comparison between model
and data can be used to constrain planet formation and migration mechanisms.Comment: 16 pages, 10 figure
The VLTI/MIDI survey of massive young stellar objects - Sounding the inner regions around intermediate- and high-mass young stars using mid-infrared interferometry
We aim to characterize the distribution and composition of circumstellar
material around young massive stars, and to investigate exactly which physical
structures in these objects are probed by long-baseline mid-infrared
interferometric observations. We used the two-telescope interferometric
instrument MIDI of the Very Large Telescope Interferometer of the European
Southern Observatory to observe a sample of 24 intermediate- and high-mass
young stellar objects in the N band (8-13 micron). We had successful fringe
detections for 20 objects, and present spectrally-resolved correlated fluxes
and visibility levels for projected baselines of up to 128 m. We fit the
visibilities with geometric models to derive the sizes of the emitting regions,
as well as the orientation and elongation of the circumstellar material.
Fourteen objects in the sample show the 10 micron silicate feature in
absorption in the total and correlated flux spectra. For 13 of these objects,
we were able to fit the correlated flux spectra with a simple absorption model,
allowing us to constrain the composition and absorptive properties of the
circumstellar material. Nearly all of the massive young stellar objects
observed show significant deviations from spherical symmetry at mid-infrared
wavelengths. In general, the mid-infrared emission can trace both disks and
outflows, and in many cases it may be difficult to disentangle these components
on the basis of interferometric data alone, because of the sparse spatial
frequency coverage normally provided by current long-baseline interferometers.
For the majority of the objects in this sample, the absorption occurs on
spatial scales larger than those probed by MIDI. Finally, the physical extent
of the mid-infrared emission around these sources is correlated with the total
luminosity, albeit with significant scatter.Comment: 36 pages, 22 figures. Accepted to Astronomy and Astrophysic
Validation of the italian translation of the affective neuroscience personality scales
Summary.-The theoretical perspective on affective neuroscience advanced by Panksepp, identified six basic innate affective systems: the SEEK, FEAR, ANGER, SADNESS, PLAY, and CARE systems. (3) It has been proposed that the fundamental elements of human personality and its variants may be based on the different expressions of these basic emotional systems and their combinations. A self-report inventory, the Affective Neuroscience Personality Scales (ANPS), has been devised with the aim of studying and evaluating personality from this perspective. This study reports data on the initial validation of ANPS Italian translation on a sample of 418 adult participants. Descriptive statistics for each scale were calculated, assessing also their internal consistency, as a measure of reliability and factorial validity. Acceptable internal consistency was found in all but one scale (SADNESS), and a second-order factor analysis identified a more general affective feature of personality hinging on relational characteristics, independent of the dimensions of general positive and negative affect
A Medium Survey of the Hard X-Ray Sky with ASCA. II.: The Source's Broad Band X-Ray Spectral Properties
A complete sample of 60 serendipitous hard X-ray sources with flux in the
range \ecs to \ecs (2 - 10
keV), detected in 87 ASCA GIS2 images, was recently presented in literature.
Using this sample it was possible to extend the description of the 2-10 keV
LogN(>S)-LogS down to a flux limit of \ecs (the
faintest detectable flux), resolving about a quarter of the Cosmic X-ray
Background. In this paper we have combined the ASCA GIS2 and GIS3 data of these
sources to investigate their X-ray spectral properties using the "hardness"
ratios and the "stacked" spectra method. Because of the sample statistical
representativeness, the results presented here, that refer to the faintest hard
X-ray sources that can be studied with the current instrumentation, are
relevant to the understanding of the CXB and of the AGN unification scheme.Comment: 28 pages plus 6 figures, LaTex manuscript, Accepted for publication
in the Astrophysical Journal, Figure 5 can retrieved via anonymous ftp at
ftp://ftp.brera.mi.astro.it/pub/ASCA/paper2/fig5.ps.g
Resource use of crucian carp along a lake productivity gradient is related to body size, predation risk, and resource competition
Generalist fish species can feed on a wide resource spectrum and across trophic levels depending on resource availability and trophic interactions. Crucian carp (Carassius carassius) represents a good candidate species to investigate variation in the trophic ecology of generalist fish as it can be found in highly variable fish communities and its resource use is well documented. In this study, we explored the trophic ecology of crucian carp at the individual and population levels using stable isotope and gut content analysis. We tested if trophic resource use varied according to lake productivity, predation risk, intra- and interspecific competition, or individual fish size. We found that crucian carp resource preference was highly variable among and within lakes. In predator-free lakes, small crucian carp occurred in high densities, showed increased interindividual specialisation, and relied mainly on pelagic zooplankton. In presence of predators, large crucian carp occurred in low densities and included greater proportions of benthic macroinvertebrates in their diet. This shift in resource use was further favoured in productive, shallow lakes where littoral prey were probably abundant. Resource partitioning was an important factor determining crucian carp niche use, as fish had higher trophic position in absence of other cyprinids. Crucian carp showed highly dynamic resource use and food preferences in response to variable environmental conditions. Overlooking complex diet preferences of generalist fish may lead to an oversimplification of freshwater community dynamics.Peer reviewe
Resource use of crucian carp along a lake productivity gradient is related to body size, predation risk, and resource competition
Generalist fish species can feed on a wide resource spectrum and across trophic levels depending on resource availability and trophic interactions. Crucian carp (Carassius carassius) represents a good candidate species to investigate variation in the trophic ecology of generalist fish as it can be found in highly variable fish communities and its resource use is well documented. In this study, we explored the trophic ecology of crucian carp at the individual and population levels using stable isotope and gut content analysis. We tested if trophic resource use varied according to lake productivity, predation risk, intra- and interspecific competition, or individual fish size. We found that crucian carp resource preference was highly variable among and within lakes. In predator-free lakes, small crucian carp occurred in high densities, showed increased interindividual specialisation, and relied mainly on pelagic zooplankton. In presence of predators, large crucian carp occurred in low densities and included greater proportions of benthic macroinvertebrates in their diet. This shift in resource use was further favoured in productive, shallow lakes where littoral prey was probably abundant. Resource partitioning was an important factor determining crucian carp niche use, as fish had higher trophic position in absence of other cyprinids. Crucian carp showed highly dynamic resource use and food preferences in response to variable environmental conditions. Overlooking complex diet preferences of generalist fish may lead to an oversimplification of freshwater community dynamics.publishedVersio
Phase field approach to optimal packing problems and related Cheeger clusters
In a fixed domain of we study the asymptotic behaviour of optimal
clusters associated to -Cheeger constants and natural energies like the
sum or maximum: we prove that, as the parameter converges to the
"critical" value , optimal Cheeger clusters
converge to solutions of different packing problems for balls, depending on the
energy under consideration. As well, we propose an efficient phase field
approach based on a multiphase Gamma convergence result of Modica-Mortola type,
in order to compute -Cheeger constants, optimal clusters and, as a
consequence of the asymptotic result, optimal packings. Numerical experiments
are carried over in two and three space dimensions
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