米飯, 食パン, レトルト米飯のレジスタントスターチの定量

In order to examine and compare the content of resistant starch (RS) under different conditions, the amount of non-starch polysaccharides (NSP) in boiled rice (A. boiled, B. boiled and frozen and defrosted), purchased bread (A. just after purchase, B. frozen and defrosted), and retort rice (A. microwaved, B. microwaved and frozen and defrosted) were measured using the Englyst method. The results were as follows: There was no difference in the content of NSP in the boiled rice A and B. The amount of NSP content in the purchased bread A was lower than that in the purchased bread B. Therefore, we could not calculate the amount of RS. The NSP content of the retort rice B was higher than that of the retort rice A. The RS content of the retort rice was 1.0±0.8 (g/100 g). The NSP content of the purchased bread was significantly higher than that of the boiled rice and retort rice

米飯, 食パンの摂取が便性に与える影響について : レジスタントスターチの作用解明へのステップ

As a step toward detecting the role of resistant starch (RS), the effects of boiled rice or bread intake on evacuation were examined. Ten subjects aged 21-22 were fed two types of prescribed diets of 3 meals per day for 7 successive days. Each type consisted of a different staple food; boiled rice or bread. The subjects were fed the same type of meal for 7 days and the frequency and amount of evacuation was recorded by the subjects. Analyzing the data showed the following results. The estimated total fiber contained in the bread each subject consumed was 6.3 g/day, and the estimated total fiber contained in boiled rice was 1.4 g/day. That is, there was 4.5 times more total fiber in bread than in rice. The frequency and amount of the evacuation tended to increase when boiled rice was ingested compared with the period when bread was ingested. Based on these results, we suggest that the fibers in the boiled rice lead to an increase in the frequency and amount of stools as compared with the fiber found in bread. We speculate that more RS is contained in the boiled rice than in the bread

PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover

The essential involvement of phosphoinositides in synaptic plasticity is well-established, but incomplete knowledge of the downstream molecular entities prevents us from understanding their signalling cascades completely. Here, we determined that Phldb2, of which pleckstrin-homology domain is highly sensitive to PIP3, functions as a phosphoinositide-signalling mediator for synaptic plasticity. BDNF application caused Phldb2 recruitment toward postsynaptic membrane in dendritic spines, whereas PI3K inhibition resulted in its reduced accumulation. Phldb2 bound to postsynaptic scaffolding molecule PSD-95 and was crucial for localization and turnover of PSD-95 in the spine. Phldb2 also bound to GluA1 and GluA2. Phldb2 was indispensable for the interaction between NMDA receptors and CaMKII, and the synaptic density of AMPA receptors. Therefore, PIP3-responsive Phldb2 is pivotal for induction and maintenance of LTP. Memory formation was impaired in our Phldb2−/− mice

ICT による気象情報の農業への活用 －宮城県産オリーブ葉のポリフェノール含量に及ぼす気象条件の影響－

本研究では先に報告している石巻市網地島、仙台市国見ケ丘、感性福祉研究所中庭において採取されたオリーブ葉ポリフェノールの含量の違いを気候データに着目して検討を行った。具体的には、各気候データを説明変数、オリーブ葉ポリフェノール含量を目的変数として回帰分析を実施し、得られた決定係数を比較した。その結果、ポリフェノール含量には気温が影響することが明らかとなった。journal articl

Dry swing training with a light bat increases bat speed

Baseball training usually includes dry swing training to improve batting ability. However, no consensus has been reached on the relationship between bat weight and the increase in post-dry swing training bat speed. We hypothesized that dry swing training with a light bat would increase post dry swing training bat speed. Therefore, the purpose of this study was to examine the effect of dry swing training with a light bat on post dry swing training bat speed by comparing a light bat group with a heavy bat group. A total of 34 healthy male students from a university baseball team were randomly divided into a light bat group (n = 17) and a heavy bat group (n = 17). Subjects performed 100 dry swings per day, twice a week for eight weeks. The light bat group performed dry swing training with a 10.6 oz bat and the heavy bat group with a 38.8 oz bat. Bat speed and muscle power were measured before and after the intervention. There was no interaction between the intervention and post dry swing training bat speed, knee extension strength, shoulder horizontal flexion, or hand grip strength. There was a main effect of the intervention on post dry swing training bat speed and shoulder horizontal flexion. Bat speed increased in both groups, but without significant group differences in intervention effects. Since light bat loads in this study were very low, dry swing training with a light bat may be more effective and less strenuous

Long-Term Outcome of Proton Therapy and Carbon-Ion Therapy for Large (T2a–T2bN0M0) Non–Small-Cell Lung Cancer

IntroductionAlthough many reports have shown the safety and efficacy of stereotactic body radiotherapy (SBRT) for T1N0M0 non–small-cell lung cancer (NSCLC), it is rather difficult to treat T2N0M0 NSCLC, especially T2b (>5 cm) tumor, with SBRT. Our hypothesis was that particle therapy might be superior to SBRT in T2 patients. We evaluated the clinical outcome of particle therapy for T2a/bN0M0 NSCLC staged according to the 7th edition of the International Union Against Cancer (UICC) tumor, node, metastasis classification.MethodsFrom April 2003 to December 2009, 70 histologically confirmed patients were treated with proton (n = 43) or carbon-ion (n = 27) therapy according to institutional protocols. Forty-seven patients had a T2a tumor and 23 had a T2b tumor. The total dose and fraction (fr) number were 60 (Gray equivalent) GyE/10 fr in 20 patients, 52.8 GyE/4 fr in 16, 66 GyE/10 fr in 16, 80 GyE/20 fr in 14, and other in four patients, respectively. Toxicities were scored according to the Common Terminology Criteria for Adverse Events, Version 4.0.ResultsThe median follow-up period for living patients was 51 months (range, 24–103). For all 70 patients, the 4-year overall survival, local control, and progression-free survival rates were 58% (T2a, 53%; T2b, 67%), 75% (T2a, 70%; T2b, 84%), and 46% (T2a, 43%; T2b, 52%), respectively, with no significant differences between the two groups. The 4-year regional recurrence rate was 17%. Grade 3 pulmonary toxicity was observed in only two patients.ConclusionParticle therapy is well tolerated and effective for T2a/bN0M0 NSCLC. To further improve treatment outcome, adjuvant chemotherapy seems a reasonable option, whenever possible

A Study on In-Service Training for Improving the Professional Development of Teaching Physical Education in Elementary Schools

First this study aims to clarify how elementary school teachers of B Prefecture informed their learning outcomes by in-service training of physical activities to their school colleagues. Secondary this study aims to clarify how in-service training of physical activities at D Elementary School in C City influenced improving school teachers' teaching in physical education. The results are summarized as following points. 1. Elementary school teachers of B Prefecture informed their learning outcomes to their school colleagues through 'in-service training meetings within their schools' or 'their daily job'. 2. D Elementary School Teachers have taught new teaching materials as learning outcomes from ‘in-service training meetings of physical activities'. 3. Teacher X and Teacher Y learned teaching method and subject knowledge of physical education by team teaching experiences with PE coordinators as 'their daily job'. Teacher L learned the way of making unit plan, modification of activities and management of his class from his elder colleague K by dialogues about teaching in physical education as 'their daily job'. 4. It seems that it is important we make mentors' daily supports to mentees between PE coordinators and other school teachers.本研究の一部は,科学研究費補助金(基盤B)課題研究番号24300212の補助によ

Magnetized Fast Isochoric Laser Heating for Efficient Creation of Ultra-High-Energy-Density States

The quest for the inertial confinement fusion (ICF) ignition is a grand challenge, as exemplified by extraordinary large laser facilities. Fast isochoric heating of a pre-compressed plasma core with a high-intensity short-pulse laser is an attractive and alternative approach to create ultra-high-energy-density states like those found in ICF ignition sparks. This avoids the ignition quench caused by the hot spark mixing with the surrounding cold fuel, which is the crucial problem of the currently pursued ignition scheme. High-intensity lasers efficiently produce relativistic electron beams (REB). A part of the REB kinetic energy is deposited in the core, and then the heated region becomes the hot spark to trigger the ignition. However, only a small portion of the REB collides with the core because of its large divergence. Here we have demonstrated enhanced laser-to-core energy coupling with the magnetized fast isochoric heating. The method employs a kilo-tesla-level magnetic field that is applied to the transport region from the REB generation point to the core which results in guiding the REB along the magnetic field lines to the core. 7.7 $\pm$ 1.3 % of the maximum coupling was achieved even with a relatively small radial area density core ($\rho R$ $\sim$ 0.1 g/cm$^2$). The guided REB transport was clearly visualized in a pre-compressed core by using Cu-$K_\alpha$ imaging technique. A simplified model coupled with the comprehensive diagnostics yields 6.2\% of the coupling that agrees fairly with the measured coupling. This model also reveals that an ignition-scale areal density core ($\rho R$ $\sim$ 0.4 g/cm$^2$) leads to much higher laser-to-core coupling ($>$ 15%), this is much higher than that achieved by the current scheme

イガン ニ タイスル da Vinci シュジュツ ノ ケイケン

The da Vinci Surgical System is a telerobotic system consisting of４components, including the Insite vision system with a true３‐dimensional endoscope providing a high-resolution binocular view of the surgical field, and the Endo Wrist instrument system, which is capable of７degrees of freedom and２degrees of axial rotation to replicate human wrist-like movements. Distal gastrectomy and D１＋lymphnode dissection was performed in a７３-year-old man with cT１bN０N０StageIA gastric cancer. Preoperative abdominal CT findings were showed that celiac artery branching patterns was Adachi VI type２６groups. The operating time was４３３minutes, and the blood loss was２８４g. The da Vinci Surgical System has useful advantages over conventional Laproscopic Assisted gastrectomy（LAG）surgery concerning the precise lymphnodes dissection. With further innovations in the future, the da Vinci Surgical System has the potential to facilitate technically difficult surgery employing conventional LAG techniques