1-(4-Chloro­phen­yl)-3-(2-nitro­phenyl)propane-1,2-dione

The title compound, C15H10ClNO4, belongs to the class of 1,2-diketones, which have important applications in both synthetic organic chemistry and supra­molecular chemistry. A dihedral angle of 9.03 (1)° is found between the mean planes of the two benzene rings. C—H⋯O inter­actions help to stabilize the crystal structure

2,2′-(3,3′-Dihexyl-2,2′-bithio­phene-5,5′-di­yl)bis­(4,4,5,5-tetra­methyl-1,3,2-dioxaborolane)

In the title mol­ecule, C32H52B2O4S2, the two thio­phene rings are twisted by 67.34 (2)°. In the crystal, weak C—H⋯O hydrogen bonds link mol­ecules related by translation along the a axis into chains

Robust Adaptive Control of STATCOMs to Mitigate Inverter-Based-Resource (IBR)-Induced Oscillations

The interaction among inverter-based resources (IBRs) and power network may cause small-signal stability issues, especially in low short-circuit grids. Besides, the integration of static synchronous compensators (STATCOMs) in a multi-IBR system for voltage support can deteriorate small-signal stability. However, it is still challenging to understand the impact mechanism of STATCOMs on IBR-induced oscillation issues and to design STATCOMs' control for damping these oscillation issues in a multi-IBR system, due to complex system dynamics and varying operating conditions. To tackle these challenges, this paper proposes a novel method to reveal how STATCOMs influence IBR-induced oscillation issues in a multi-IBR system from the viewpoint of grid strength, which can consider varying operating conditions. Based on this proposed method, we find critical operating conditions, wherein the system tends to be most unstable; moreover, we demonstrate that robust small-signal stability issues of the multi-IBR system with STATCOMs can be simplified as that of multiple subsystems under critical operating conditions, which avoids traversing all operating conditions and establishing system's detailed models. On this basis, an adaptive control-parameter design method is proposed for STATCOMs to ensure system's robust small-signal stability under varying operating conditions. The efficacy of proposed methods is validated by a 39-node test system

Robust stability for stochastic Hopfield neural networks with time delays

This is the post print version of the article. The official published version can be obtained from the link below - Copyright 2006 Elsevier Ltd.In this paper, the asymptotic stability analysis problem is considered for a class of uncertain stochastic neural networks with time delays and parameter uncertainties. The delays are time-invariant, and the uncertainties are norm-bounded that enter into all the network parameters. The aim of this paper is to establish easily verifiable conditions under which the delayed neural network is robustly asymptotically stable in the mean square for all admissible parameter uncertainties. By employing a Lyapunov–Krasovskii functional and conducting the stochastic analysis, a linear matrix inequality (LMI) approach is developed to derive the stability criteria. The proposed criteria can be checked readily by using some standard numerical packages, and no tuning of parameters is required. Examples are provided to demonstrate the effectiveness and applicability of the proposed criteria.This work was supported in part by the Engineering and Physical Sciences Research Council (EPSRC) of the UK under Grant GR/S27658/01, the Nuffield Foundation of the UK under Grant NAL/00630/G, and the Alexander von Humboldt Foundation of German

Almost sure state estimation with H2-type performance constraints for nonlinear hybrid stochastic systems

This paper is concerned with the problem of almost sure state estimation for general nonlinear hybrid stochastic systems whose coefficients only satisfy local Lipschitz conditions. By utilizing the stopping time method combined with martingale inequalities, a theoretical framework is established for analyzing the so-called almost surely asymptotic stability of the addressed system. Within such a theoretical framework, some sufficient conditions are derived under which the estimation dynamics is almost sure asymptotically stable and the upper bound of estimation error is also determined. Furthermore, a suboptimal state estimator is obtained by solving an optimization problem in the H2 sense. According to the obtained results, for a class of special nonlinear hybrid stochastic systems, the corresponding conditions reduce to a set of matrix inequalities for the purpose of easy implementation. Finally, two numerical simulation examples are used to demonstrate the effectiveness of the results derived.This work was supported in part by the National Natural Science Foundation of China under Grants 61134009 and 61329301, the Royal Society of the UK, and the Alexander von Humboldt Foundation of Germany

Almost sure H∞ sliding mode control for nonlinear stochastic systems with Markovian switching and time-delays

This paperinvestigatesthealmostsure H1 sliding mode control (SMC) problem for non linear stochastic systems with Markovian switching and time-delays. An integral sliding surface is first constructed for the addressed system. Then, by employing the topping time method combined with martingale in equalities, sufficient conditions are established to ensure the almost surely exponential stability and the H 1 performance of the system dynamics in the specified sliding surface. ASMC law is designed to guarantee the reach ability of the specified sliding surface almost surely. Furthermore, the obtained results are applied to a class of special nonlinear stochastic systems with Markovian switching and time-delays, where the desired SMC law is obtained in terms of the solutions to a set of matrix in equalities. Finally, a numerical example is given to show the effectiveness of the proposed SMC scheme

Co-infusion of haplo-identical CD19-chimeric antigen receptor T cells and stem cells achieved full donor engraftment in refractory acute lymphoblastic leukemia

Abstract Background Elderly patients with relapsed and refractory acute lymphoblastic leukemia (ALL) have poor prognosis. Autologous CD19 chimeric antigen receptor-modified T (CAR-T) cells have potentials to cure patients with B cell ALL; however, safety and efficacy of allogeneic CD19 CAR-T cells are still undetermined. Case presentation We treated a 71-year-old female with relapsed and refractory ALL who received co-infusion of haplo-identical donor-derived CD19-directed CAR-T cells and mobilized peripheral blood stem cells (PBSC) following induction chemotherapy. Undetectable minimal residual disease by flow cytometry was achieved, and full donor cell engraftment was established. The transient release of cytokines and mild fever were detected. Significantly elevated serum lactate dehydrogenase, alanine transaminase, bilirubin and glutamic-oxalacetic transaminase were observed from days 14 to 18, all of which were reversible after immunosuppressive therapy. Conclusions Our preliminary results suggest that co-infusion of haplo-identical donor-derived CAR-T cells and mobilized PBSCs may induce full donor engraftment in relapsed and refractory ALL including elderly patients, but complications related to donor cell infusions should still be cautioned. Trial registration Allogeneic CART-19 for Elderly Relapsed/Refractory CD19+ ALL. NCT0279955

A Comprehensive Study of the Electrostatic Discharge Sensitivity and Chargeability of Tris(carbohydrazide)zinc Perchlorate

Abstract: Most primary explosives are non-conductors, easily accumulate charge when contacting with and separating from other materials, and are sensitive to electrostatic discharge (ESD). In order to reduce the number of accidents caused by ESD initiation of primary explosives, studies on their electrostatic hazards are necessary. This work presents comprehensive experimental results of electrostatic discharge sensitivity and chargeability of tris(carbohydrazide)zinc perchlorate (ZnCP) under different conditions. The influences of the testing conditions, of devices, particle size, ambient temperature and relative humidity on the electrostatic discharge sensitivity and chargeability have been investigated in detail, and the quantitative regression equations obtained