A feasibility study of auricular therapy and self-administered acupressure for insomnia following cancer treatment

Introduction: Many cancer patients experience sleeping difficulties which can persist several years after the completion of cancer treatment. Previous research suggests that acupuncture, and variants of acupuncture (acupressure, auricular therapy) may be effective treatment options for sleep disturbance. However, current evidence is limited for cancer patients. Methods: Feasibility study with 3 arms. Seven cancer patients with insomnia randomised to receive either auricular therapy (attaching semen vaccariae seeds to ear acupoints) (n = 4), self-acupressure (n= 1) or no treatment (n= 2). Participants assigned to receive auricular therapy or self-acupressure stimulated the acupoints each night an hour before retiring to bed. The duration of participant involvement was 5 weeks. Subjective sleep quality was measured at baseline and post-treatment using the Pittsburgh sleep quality index (PSQI). The impact of treatment on concerns of importance to the participants themselves was measured using the measure yourself concerns and wellbeing (MYCaW). Each participant also completed a treatment log book. Results: All participants completed their treatment. All auricular therapy and self-acupressure participants recorded clinically significant improvements in global PSQI scores. In the auricular therapy arm mean global PSQI reduced from 12.5 at baseline to 8 following completion of treatment. In the self-acupressure arm PSQI reduced from 15 to 11. While in the no treatment arm the mean PSQI score was 14.5 at both baseline and follow up. Conclusions: Despite the limited sample size, both auricular therapy and self-acupressure may represent potentially effective treatments for cancer patients with insomnia. The positive findings suggest further research is warranted into both treatment modalities.School of Nursin

Stabilized finite element methods : I. application to the advective-diffusive model

Projet MODULE

In search of hair damage using metabolomics?

YesHair fibres are extraordinary materials, not least because they are exquisitely formed by each of the 5 million or so hair follicles on our bodies and have functions that cross from physiology to psychology, but also because they have well known resistance to degradation as seen in hair surviving from archaeological and historical samples [1]. Hair fibres on the head grow at around 1cm each month, together totalling approximately 12km of growth per person per year. Each fibre is incredibly strong for its small diameter; with one fibre typically holding 100g and together a well-formed ponytail [allegedly] has the collective strength to support the weight of a small elephant! Hair – and from here I mean scalp hair – is under constant scrutiny by each of us; whether it be style, split ends, the first few grey hairs or the collection of hairs in the shower that should be firmly attached - leading to the fear that is hair loss

Higher spins dynamics in the closed string theory

The general $\sigma$-model-type string action including both massless and massive higher spins background fields is suggested. Field equations for background fields are followed from the requirement of quantum Weyl invariance. It is shown that renormalization of the theory can be produced level by level. The detailed consideration of background fields structure and corresponding fields equations is given for the first massive level of the closed bosonic string.Comment: 11 pages, report TSU/QFTD-36/9

A New Transport Regime in the Quantum Hall Effect

This paper describes an experimental identification and characterization of a new low temperature transport regime near the quantum Hall-to-insulator transition. In this regime, a wide range of transport data are compactly described by a simple phenomenological form which, on the one hand, is inconsistent with either quantum Hall or insulating behavior and, on the other hand, is also clearly at odds with a quantum-critical, or scaling, description. We are unable to determine whether this new regime represents a clearly defined state or is a consequence of finite temperature and sample-size measurements.Comment: Revtex, 3 pages, 2 figure

Effects of finite arm-length of LISA on analysis of gravitational waves from MBH binaries

Response of an interferometer becomes complicated for gravitational wave shorter than the arm-length of the detector, as nature of wave appears strongly. We have studied how parameter estimation for merging massive black hole binaries are affected by this complicated effect in the case of LISA. It is shown that three dimensional positions of some binaries might be determined much better than the past estimations that use the long wave approximation. For equal mass binaries this improvement is most prominent at \sim 10^5\sol.Comment: 10 pages, 3 figures, to appear in Phys.Rev.

The Nature of the Hall Insulator

We have conducted an experimental study of the linear transport properties of the magnetic-field induced insulating phase which terminates the quantum Hall (QH) series in two dimensional electron systems. We found that a direct and simple relation exists between measurements of the longitudinal resistivity, $\rho_{xx}$, in this insulating phase and in the neighboring QH phase. In addition, we find that the Hall resistivity, $\rho_{xy}$, can be quantized in the insulating phase. Our results indicate that a close relation exists between the conduction mechanism in the insulator and in the QH liquid.Comment: RevTeX, 4 pages, 4 figure

Bottom-Up and Top-Down Processes in Emotion Generation: Common and Distinct Neural Mechanisms

Emotions are generally thought to arise through the interaction of bottom-up and top-down processes. However, prior work has not delineated their relative contributions. In a sample of 20 females, we used functional magnetic resonance imaging to compare the neural correlates of negative emotions generated by the bottom-up perception of aversive images and by the top-down interpretation of neutral images as aversive. We found that (a) both types of responses activated the amygdala, although bottom-up responses did so more strongly; (b) bottom-up responses activated systems for attending to and encoding perceptual and affective stimulus properties, whereas top-down responses activated prefrontal regions that represent high-level cognitive interpretations; and (c) self-reported affect correlated with activity in the amygdala during bottom-up responding and with activity in the medial prefrontal cortex during top-down responding. These findings provide a neural foundation for emotion theories that posit multiple kinds of appraisal processes and help to clarify mechanisms underlying clinically relevant forms of emotion dysregulation.National Institutes of Health (U.S.) (Grant MH58147)National Institutes of Health (U.S.) (Grant MH076137