94 research outputs found

    Cooperación Documental : el caso de México.

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    El siguiente trabajo presenta los canales de cooperación que han desarrollado las instituciones documentales de México. Expone un panorama general en el que para ubicar las relaciones con mayor claridad, se incluyen los tipos de bibliotecas, las actividades profesionales, la formación bibliotecaria y la investigación, el impacto de la tecnología, la cooperación documental y los recursos informativos que apoyan dichos canalesThis work introduces the cooperation channels developed by the documental bodies in México. It describes a general panorama in which are included, so as to give a clear idea as to relationships, the types of libraries, professional activities, librarianship training and research, the impact of technology, document cooperation and the information resources supporting the aforementioned channels

    Servicio de análisis del impacto de la productividad científica del Instituto de Investigaciones Jurídicas de la UNAM

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    Depto. de Biblioteconomía y DocumentaciónFac. de Ciencias de la DocumentaciónTRUEpu

    Buenas Prácticas de los Recursos Humanos ante el trabajo híbrido en Bibliotecas de Investigación

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    Fac. de Ciencias de la DocumentaciónFac. de Ciencias de la InformaciónTRUEpu

    Aportaciones a la Historia de la Documentación: evolución y contexto historiográfico

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    Repaso a la historia de la Documentación a través de las grandes civilizaciones y las distintas etapas que han conformado lo que hoy es la cultura occidental: desde el imperio asirio hasta el siglo XVIII o “Siglo de las luces”. A través de este estudio podemos comprender cuál ha sido la evolución y los inicios que han conformado lo que hoy entendemos por Documentación

    Contenidos para el aprendizaje de materias de carácter económico en la titulación de arquitectura

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    Este trabajo se propone establecer las bases de la formación de los alumnos en la adquisición de los conocimientos necesarios sobre la economía aplicada al ejercicio profesional de la arquitectura. La determinación de los contenidos propios de la disciplina constituye el elemento fundamental. Se propone establecer las bases de la formación de los alumnos en la adquisición de los conocimientos necesarios para determinar el impacto económico de las decisiones de proyecto; las técnicas de medición y cuantificación de unidades de obra y de la predicción de costes de construcción en el proyecto arquitectónico; la utilización de recursos informáticos para la gestión de costes en el proceso de edificación y a metodología y las técnicas necesarias para la valoración de bienes inmuebles

    Qualitas scientiae database: applying qualitative citation analysis to Spanish journals of information science (1996-2004)

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    The Qualitas Scientiae database is the result of an application of Qualitative Citation methodology to Spanish Journals in the field of Information Science in the period between 1996 and 2004. The sample of journals follows that of database IN-RECS, developed by the University of Granada. In turn, the findings of Qualitas Scientiae are compared to those of IN-RECS

    Criterios para la evaluación de tesis doctorales

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    In this paper, we propose a questionnaire directed at accurately assessing the quality of doctoral dissertations in its different stages, both a-priori, in the doctoral defence, and a-posteriori, whenever the dissertation be newly assessed as part of an application for a research grant, prize, etc. These criteria are independent of a further assessment of the dissertation as a published text.El presente trabajo tiene por objeto proponer el texto de un cuestionario o test que permita la evaluación de las tesis doctoral de modo minucioso en las fases de evaluación a priori, en el acto académico de presentación y defensa y a posteriori cuando la tesis sea susceptible de nueva evaluación en las convocatorias de premio extraordinario o en las solicitudes de concesión de becas o proyectos de investigación sin perjuicio de su evaluación como trabajo científico una vez publicado

    Seroprevalence of Toxoplasma gondii infection and associated risk factors in Huicholes in Mexico

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    BACKGROUND: Very little is known about the seroepidemiology of Toxoplasma gondii infection in ethnic groups in Mexico. Huicholes are an indigenous ethnic group living in a remote mountainous region in Mexico. We sought to determine the prevalence of anti-Toxoplasma IgG and IgM antibodies in Huicholes; and to determine the association of Toxoplasma seropositivity with socio-demographic, behavioral, and clinical characteristics of Huicholes. METHODS: We performed a cross sectional survey in Huicholes from September 2013 to January 2014. A convenience sampling method was used. We investigated the prevalence of anti-Toxoplasma IgG and IgM antibodies in 214 Huicholes using enzyme-linked immunoassays. A standardized questionnaire was used to obtain the characteristics of the Huicholes. Bivariate and multivariate analyses were used to assess the association of Toxoplasma exposure and Huicholes’ characteristics. RESULTS: Of the 214 Huicholes studied (mean age: 37.98 ± 15.80 years), 71 (33.2%) were positive for anti-T. gondii IgG antibodies and 47 (66.2%) of them were also positive for anti-T. gondii IgM antibodies. Seroprevalence of T. gondii infection did not vary with age, sex, or occupation. However, seroprevalence of anti-T. gondii IgM antibodies was significantly higher in female than in male Huicholes. Multivariate analysis of socio-demographic and behavioral characteristics showed that T. gondii exposure was associated with consumption of turkey meat (OR = 2.28; 95% CI: 1.16-4.46; P = 0.01). In addition, seroprevalence of T. gondii infection was significantly higher in Huicholes suffering from dizziness and memory impairment than those without such clinical characteristics. CONCLUSIONS: Our results demonstrate serological evidence of T. gondii exposure among Huicholes which may be impacting their health. Results of this first study of T. gondii infection in Huicholes may be useful for the design of optimal preventive measures against infection with T. gondii

    Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

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    Type 2 diabetes (T2D) affects Latinos at twice the rate seen in populations of European descent. We recently identified a risk haplotype spanning SLC16A11 that explains ∼20% of the increased T2D prevalence in Mexico. Here, through genetic fine-mapping, we define a set of tightly linked variants likely to contain the causal allele(s). We show that variants on the T2D-associated haplotype have two distinct effects: (1) decreasing SLC16A11 expression in liver and (2) disrupting a key interaction with basigin, thereby reducing cell-surface localization. Both independent mechanisms reduce SLC16A11 function and suggest SLC16A11 is the causal gene at this locus. To gain insight into how SLC16A11 disruption impacts T2D risk, we demonstrate that SLC16A11 is a proton-coupled monocarboxylate transporter and that genetic perturbation of SLC16A11 induces changes in fatty acid and lipid metabolism that are associated with increased T2D risk. Our findings suggest that increasing SLC16A11 function could be therapeutically beneficial for T2D. Video Abstract [Figure presented] Keywords: type 2 diabetes (T2D); genetics; disease mechanism; SLC16A11; MCT11; solute carrier (SLC); monocarboxylates; fatty acid metabolism; lipid metabolism; precision medicin
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