26 research outputs found
Recommended from our members
Optoacoustically induced auditory brainstem responses in the mouse model enhanced through an absorbing film
Significance: Optoacoustic stimulation offers an alternative stimulation strategy for the hearing
organ. To serve as the base for a novel auditory prosthesis, the optoacoustic stimulation must be
biocompatible and energy-saving.
Aim: Enhancing the efficiency of optoacoustic stimulation while reducing the energy input in
a suited animal model.
Approach: Optoacoustically induced auditory brainstem responses (oABRs) were recorded
after the pulsed laser irradiation of the tympanic membrane (TM) in mice. The results were
compared with the ABRs induced through acoustic click stimulation. In addition, self-adhesive
absorbing films were applied on the TM before the optoacoustic stimulation to investigate their
effect on the resulting ABRs.
Results: Using an absorbing film on the TM during optical stimulation led to considerably
enhanced oABR wave I amplitude values compared with the stimulation of the bare TM.
When using our stimulation strategy, we induced oABR waves in the 50% to 60% range of
the acoustical stimulation reached with 80-dB SPL click stimuli.
Conclusions: The mouse model can be used for certain developmental work for an optoacoustic
auditory prosthesis. Using absorbing films on the TM during optical stimulation considerably
enhances oABR wave I amplitude. Optimization of the stimulation strategy could further
enhance the efficiency within biocompatibility margins
History Of Economic Doctrines : an introduction to economic theory
ix, 263 hal.; 21c
Hugo Heimann in memoriam : Speeches at the funeral services held in New York, Feb. 25, 1951.
digitizedHugo Heimann (1859-1951) was a German publisher and high ranking politician affiliated with the Social Democratic Party in Germany (SPD). Shortly after the Nazis’ rise to power he immigrated to New York via England
The need for a holistic view on management of Clostridioides difficile infection
Molecular basis of bacterial pathogenesis, virulence factors and antibiotic resistanc